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Betulinic acid methyl ester

Betulinic acid methyl ester Structure
Betulinic acid methyl ester structure
CAS No.
2259-06-5
Chemical Name:
Betulinic acid methyl ester
Synonyms
Methylbetulinate;betulinate, Methyl;Betulinic acid methyl ester;BETULINIC ACID METHYL ESTER hplc;BETULINIC ACID METHYLESTER WITH HPLC;3B-HYDROXY-LUP-20(29)-EN-28-OIC ACID METHYL ESTER;Lup-20(29)-en-28-oic acid, 3-hydroxy-, methyl ester, (3)-;Lup-20(29)-en-28-oic acid, 3-hydroxy-, methyl ester, (3β)-;Lup-20(29)-en-28-oic acid, 3-hydroxy-, methyl ester, (3beta)-
CBNumber:
CB7322703
Molecular Formula:
C31H50O3
Molecular Weight:
470.73
MDL Number:
MFCD00017379
MOL File:
2259-06-5.mol
TDS File:
TDS
Last updated:2026-09-12 18:54:55
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Betulinic acid methyl ester Properties

Melting point 222-223°C
Boiling point 523.5±33.0 °C(Predicted)
Density 1.036±0.06 g/cm3(Predicted)
pka 15.16±0.70(Predicted)
form A solid
LogP 9.400 (est)

Betulinic acid methyl ester price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 30066 Betulinic Acid methyl ester ≥95% 2259-06-5 1mg $169 2026-04-30 Buy
Cayman Chemical 30066 Betulinic Acid methyl ester ≥95% 2259-06-5 5mg $502 2026-04-30 Buy
Usbiological 379689 Betulinic acid methyl ester ≥98% 2259-06-5 10mg $479 2026-06-03 Buy
ChemScene CS-0034288 Betulinic acid methyl ester 2259-06-5 5mg $162 2026-06-04 Buy
ChemScene CS-0034288 Betulinic acid methyl ester 2259-06-5 10mg $260 2026-06-04 Buy
Product number Packaging Price Buy
30066 1mg $169 Buy
30066 5mg $502 Buy
379689 10mg $479 Buy
CS-0034288 5mg $162 Buy
CS-0034288 10mg $260 Buy

Betulinic acid methyl ester Chemical Properties, Uses, Production

Description

Betulinic acid methyl ester is a lupane-type triterpenoid and an esterified version of betulinic acid that has been found in Helicteres hirsuta and has diverse biological activities. It inhibits HIV-1 reverse transcriptase (IC50 = 11 μM). Betulinic acid methyl ester is active against L. braziliensis and T. cruzi (IC50s = 69.9 and 93.3 μM, respectively). It induces melanogenesis in (EC50 = 2.5 μM) and inhibits the growth of B16 2F2 melanoma cells in vitro (IC50 = 4.9 μM). Betulinic acid methyl ester is cytotoxic to SK-LU-1, HepG2, HeLa, SK-MEL-2, and AGS cells (IC50s = 60.84, 77.43, 80.17, 66.17, and 69.94 μg/ml, respectively).

Uses

Betulinic acid methyl ester, a betulinic acid derivative, possesses antiprotozoal activity[1].

Definition

ChEBI: Betulinic acid methyl ester is a triterpenoid.

Biological Activity

Betulinic acid methyl ester is a natural compound extracted from the bark of the birch tree with anti-inflammatory and antiprotozoal activity.  Studies have shown it to be a potent inhibitor of cancer cell growth in vitro and in vivo.  It has also been shown to have hypoglycaemic effects in mice.

References

[1] D B Domínguez-Carmona, et al. Antiprotozoal activity of betulinic acid derivatives. Phytomedicine. 2010 Apr;17(5):379-82. DOI:10.1016/j.phymed.2009.08.002

Betulinic acid methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

Betulinic acid methyl ester Suppliers

Global Suppliers ( 70)
Supplier Tel Email Country ProdList Advantage
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Chengdu Biopurify Phytochemicals Ltd. +86-028-82633397 18982077548 cwb1@biopurify.cn China 2376 60
Shanghai Hekang Biotechnology Co., Ltd. 17721021104 18939837085 2880152141@qq.com China 1840 55
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7717 56
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632; sales@reading-chemicals.com China 15165 58
Wuhan ChemFaces Biochemical Co., Ltd. 18607101326 15172504745 aileen@chemfaces.com China 6904 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai Yihe Biological Technology Co., Ltd. 021-68882955 17721395025 2423903095@qq.com China 5000 58
Chengdu Push Bio-Technology Co., Ltd. 028-85370565-229 18080489829 18080489829@163.com China 8379 60
Shanghai Han-Xiang Chemical Co., Ltd. 17754423994 candy@biochempartner.com China 3057 58
Supplier Advantage
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Chengdu Biopurify Phytochemicals Ltd. 60
Shanghai Hekang Biotechnology Co., Ltd. 55
Sichuan Wei Keqi Biological Technology Co., Ltd. 56
Wuxi Zhongkun Biochemical Technology Co., Ltd. 58
Wuhan ChemFaces Biochemical Co., Ltd. 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
Shanghai Yihe Biological Technology Co., Ltd. 58
Chengdu Push Bio-Technology Co., Ltd. 60
Shanghai Han-Xiang Chemical Co., Ltd. 58

View Latest Price from Betulinic acid methyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BETULINIC ACID METHYL ESTER pictures 2025-06-27 BETULINIC ACID METHYL ESTER
2259-06-5
 1KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd

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3B-HYDROXY-LUP-20(29)-EN-28-OIC ACID METHYL ESTER Lup-20(29)-en-28-oic acid, 3-hydroxy-, methyl ester, (3beta)- Methylbetulinate BETULINIC ACID METHYL ESTER hplc BETULINIC ACID METHYLESTER WITH HPLC Lup-20(29)-en-28-oic acid, 3-hydroxy-, methyl ester, (3β)- betulinate, Methyl Lup-20(29)-en-28-oic acid, 3-hydroxy-, methyl ester, (3)- Betulinic acid methyl ester 2259-06-5 Tri-Terpenoids