3,4-Dimethoxyphenylboronic acid
- CAS No.
- 122775-35-3
- Chemical Name:
- 3,4-Dimethoxyphenylboronic acid
- Synonyms
- Boronic acid, B-(3,4-dimethoxyphenyl)-;AKOS BRN-0064;RARECHEM AH PB 0109;3,4-Dimethoxyphenylboronic;3,4-Dimethoxy boronic acid;4-DiMethoxyphenylboronic acid;3,4-DimethoxyphenylboronicAci;3,4-DIMETHOXYPHENYLBORONIC AICD;3,4-DIMETHOXYPHENYLBORONIC ACID;3,4-DIMETHOXYBENZENEBORONIC ACID
- CBNumber:
- CB7334366
- Molecular Formula:
- C8H11BO4
- Molecular Weight:
- 181.98
- MDL Number:
- MFCD01074574
- MOL File:
- 122775-35-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 245-250 °C (lit.) |
|---|---|
| Boiling point | 336.7±52.0 °C(Predicted) |
| Density | 1.19±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | Powder and Granules |
| pka | 8.48±0.10(Predicted) |
| color | White to light beige |
| Water Solubility | 25 g/L |
| BRN | 5334877 |
| InChI | InChI=1S/C8H11BO4/c1-12-7-4-3-6(9(10)11)5-8(7)13-2/h3-5,10-11H,1-2H3 |
| InChIKey | RCVDPBFUMYUKPB-UHFFFAOYSA-N |
| SMILES | B(C1=CC=C(OC)C(OC)=C1)(O)O |
| CAS DataBase Reference | 122775-35-3(CAS DataBase Reference) |
| UNSPSC Code | 12352103 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 37/39-26-36/37 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant/Keep Cold | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29319090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
3,4-Dimethoxyphenylboronic acid price More Price(98)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 480118 | 3,4-Dimethoxyphenylboronic acid ≥95.0% | 122775-35-3 | 5g | $52.7 | 2026-04-30 | Buy |
| Sigma-Aldrich | 480118 | 3,4-Dimethoxyphenylboronic acid ≥95.0% | 122775-35-3 | 25g | $98.3 | 2026-04-30 | Buy |
| TCI Chemical | D3512 | 3,4-Dimethoxyphenylboronic Acid (contains varying amounts of Anhydride) | 122775-35-3 | 5g | $76 | 2026-04-30 | Buy |
| TCI Chemical | D3512 | 3,4-Dimethoxyphenylboronic Acid (contains varying amounts of Anhydride) | 122775-35-3 | 25g | $304 | 2026-04-30 | Buy |
| Usbiological | 273034 | 3,4-Dimethoxyphenylboronic acid Asreported | 122775-35-3 | 25g | $486 | 2026-06-03 | Buy |
3,4-Dimethoxyphenylboronic acid Chemical Properties,Uses,Production
Chemical Properties
white to light beige powder and granules
Uses
suzuki reaction
Uses
3,4-Dimethoxyphenylboronic acid can be used:
- As a substrate in the cross-coupling reaction with 5,7-dichloropyrido[4,3-d]pyrimidine catalyzed by palladium.
- As a starting material for the synthesis of buflavine 1, a natural alkaloid.
- In one of the key synthetic steps for the preparation of lipidated malarial glycosylphosphatidylinositols (GPI) disaccharide.
- To prepare 3,3″,4,4″-tetramethoxy-1,1′:4′,1″-terphenyl by reacting with 1,4-dibromobenzene using Pd catalyst.
Synthesis
6315-89-5
122775-35-3
GENERAL PROCEDURE: 3,4-Dimethoxyaniline (0.5 mmol, 1.0 eq.) was dissolved in methanol (1.0 mL), hydrochloric acid (0.5 mL, 1.5 mmol, 3.0 eq.) was slowly added, followed by water (0.5 mL). The reaction mixture was stirred for 2 min, then sodium nitrite solution (0.25 mL, prepared by dissolving 35 mg NaNO2 in 0.25 mL of water) was added. The reaction mixture was stirred at 0-5 °C for 30 min, followed by the addition of methanol (1.0 mL) and hydrochloric acid (135 mg, 1.5 mmol, 3.0 equiv). Stirring was continued for 60 min. Upon completion of the reaction, it was diluted with water (10 mL) and extracted with dichloromethane (50 mL, 3 times). The organic layers were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give 3,4-dimethoxyphenylboronic acid.
References
[1] Synlett, 2014, vol. 25, # 11, p. 1577 - 1584
3,4-Dimethoxyphenylboronic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Panjin Greenchem Technology Co., Ltd. | 13121959385 | chemrocking@bjgreenchem.com | China | 223 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 |
View Lastest Price from 3,4-Dimethoxyphenylboronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-09-11 | 3,4-Dimethoxyphenylboronic acid
122775-35-3
|
1KG | 99% | 100mt/year | Jinan Finer Chemical Co., Ltd | ||
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2026-09-02 | 3,4-Dimethoxyphenylboronic acid
122775-35-3
|
$1.20-34.00 | 1kg | 99% | Henan Fengda Chemical Co., Ltd | ||
![]() |
2026-05-28 | 3,4-Dimethoxyphenylboronic acid
122775-35-3
|
$2.00-5.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD |
-

- 3,4-Dimethoxyphenylboronic acid
122775-35-3
- $0.00
- 99%
- Jinan Finer Chemical Co., Ltd
-

- 3,4-Dimethoxyphenylboronic acid
122775-35-3
- $1.20-34.00
- 99%
- Henan Fengda Chemical Co., Ltd
-

- 3,4-Dimethoxyphenylboronic acid
122775-35-3
- $2.00-5.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
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