ChemicalBook >> CAS DataBase List >>3,4-Dimethoxyphenylboronic acid

3,4-Dimethoxyphenylboronic acid

CAS No.
122775-35-3
Chemical Name:
3,4-Dimethoxyphenylboronic acid
Synonyms
Boronic acid, B-(3,4-dimethoxyphenyl)-;AKOS BRN-0064;RARECHEM AH PB 0109;3,4-Dimethoxyphenylboronic;3,4-Dimethoxy boronic acid;4-DiMethoxyphenylboronic acid;3,4-DimethoxyphenylboronicAci;3,4-DIMETHOXYPHENYLBORONIC AICD;3,4-DIMETHOXYPHENYLBORONIC ACID;3,4-DIMETHOXYBENZENEBORONIC ACID
CBNumber:
CB7334366
Molecular Formula:
C8H11BO4
Molecular Weight:
181.98
MDL Number:
MFCD01074574
MOL File:
122775-35-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:11:00

3,4-Dimethoxyphenylboronic acid Properties

Melting point 245-250 °C (lit.)
Boiling point 336.7±52.0 °C(Predicted)
Density 1.19±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form Powder and Granules
pka 8.48±0.10(Predicted)
color White to light beige
Water Solubility 25 g/L
BRN 5334877
InChI InChI=1S/C8H11BO4/c1-12-7-4-3-6(9(10)11)5-8(7)13-2/h3-5,10-11H,1-2H3
InChIKey RCVDPBFUMYUKPB-UHFFFAOYSA-N
SMILES B(C1=CC=C(OC)C(OC)=C1)(O)O
CAS DataBase Reference 122775-35-3(CAS DataBase Reference)
UNSPSC Code 12352103
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  37/39-26-36/37
WGK Germany  3
Hazard Note  Irritant/Keep Cold
HazardClass  IRRITANT
HS Code  29319090
Storage Class 11 - Combustible Solids
NFPA 704
0
2 0

3,4-Dimethoxyphenylboronic acid price More Price(98)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 480118 3,4-Dimethoxyphenylboronic acid ≥95.0% 122775-35-3 5g $52.7 2026-04-30 Buy
Sigma-Aldrich 480118 3,4-Dimethoxyphenylboronic acid ≥95.0% 122775-35-3 25g $98.3 2026-04-30 Buy
TCI Chemical D3512 3,4-Dimethoxyphenylboronic Acid (contains varying amounts of Anhydride) 122775-35-3 5g $76 2026-04-30 Buy
TCI Chemical D3512 3,4-Dimethoxyphenylboronic Acid (contains varying amounts of Anhydride) 122775-35-3 25g $304 2026-04-30 Buy
Usbiological 273034 3,4-Dimethoxyphenylboronic acid Asreported 122775-35-3 25g $486 2026-06-03 Buy
Product number Packaging Price Buy
480118 5g $52.7 Buy
480118 25g $98.3 Buy
D3512 5g $76 Buy
D3512 25g $304 Buy
273034 25g $486 Buy

3,4-Dimethoxyphenylboronic acid Chemical Properties,Uses,Production

Chemical Properties

white to light beige powder and granules

Uses

suzuki reaction

Uses

3,4-Dimethoxyphenylboronic acid can be used:

  • As a substrate in the cross-coupling reaction with 5,7-dichloropyrido[4,3-d]pyrimidine catalyzed by palladium.
  • As a starting material for the synthesis of buflavine 1, a natural alkaloid.
  • In one of the key synthetic steps for the preparation of lipidated malarial glycosylphosphatidylinositols (GPI) disaccharide.
  • To prepare 3,3″,4,4″-tetramethoxy-1,1′:4′,1″-terphenyl by reacting with 1,4-dibromobenzene using Pd catalyst.

Synthesis

4-Aminoveratrole

6315-89-5

3,4-Dimethoxyphenylboronic acid

122775-35-3

GENERAL PROCEDURE: 3,4-Dimethoxyaniline (0.5 mmol, 1.0 eq.) was dissolved in methanol (1.0 mL), hydrochloric acid (0.5 mL, 1.5 mmol, 3.0 eq.) was slowly added, followed by water (0.5 mL). The reaction mixture was stirred for 2 min, then sodium nitrite solution (0.25 mL, prepared by dissolving 35 mg NaNO2 in 0.25 mL of water) was added. The reaction mixture was stirred at 0-5 °C for 30 min, followed by the addition of methanol (1.0 mL) and hydrochloric acid (135 mg, 1.5 mmol, 3.0 equiv). Stirring was continued for 60 min. Upon completion of the reaction, it was diluted with water (10 mL) and extracted with dichloromethane (50 mL, 3 times). The organic layers were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give 3,4-dimethoxyphenylboronic acid.

References

[1] Synlett, 2014, vol. 25, # 11, p. 1577 - 1584

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View Lastest Price from 3,4-Dimethoxyphenylboronic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,4-Dimethoxyphenylboronic acid pictures 2026-09-11 3,4-Dimethoxyphenylboronic acid
122775-35-3
1KG 99% 100mt/year Jinan Finer Chemical Co., Ltd
3,4-Dimethoxyphenylboronic acid pictures 2026-09-02 3,4-Dimethoxyphenylboronic acid
122775-35-3
$1.20-34.00 1kg 99% Henan Fengda Chemical Co., Ltd
3,4-Dimethoxyphenylboronic acid pictures 2026-05-28 3,4-Dimethoxyphenylboronic acid
122775-35-3
$2.00-5.00 1KG 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
3,4-Dimethoxyphenylboronic 3,4-DIMETHOXYPHENYLBORONIC AICD 3,4-Dimethoxyphenylboronic Acid (contains varying amounts of Anhydride) 3,4-Dimethoxyphenylboronic acid,97% Boronicacid, (3,4-dimethoxyphenyl)- (9CI) BORONICACID, (3,4-DIMETHOXYPHENYL)- (9CI); 3,4-Dimethoxyphenylboronic acid ,98% (3,4-dimethoxyphenyl)boronic acid(SALTDATA: FREE) 4-DiMethoxyphenylboronic acid 3,4-DiMethoxyphenylboronic acid, 97% 1GR 3,4-DiMethoxyphenylboronic acid, 97% 5GR 3,4-Dimethoxyphenylboronic acid >=95.0% (3,4-dimethoxyphenyl)boronic acid - boric acid 3,4-Dimethoxyphenylboronic acid (contain Anhydride) (3,4-dimethoxyphenyl)boronic acid - boric acid (1:1) AKOS BRN-0064 3,4-DIMETHOXYBENZENEBORONIC ACID 3,4-DIMETHOXYPHENYLBORONIC ACID RARECHEM AH PB 0109 3,4-Dimethoxy boronic acid 3,4-DimethoxyphenylboronicAci 3,4-Dimethoxybenzeneboronic acid, 95% 3,4-Dimethoxyphenylboronic acid - [D2780] Boronic acid, B-(3,4-dimethoxyphenyl)- 122775-35-3 192128-54-0 122775-35-2 C8H11BO4 C8H11BO4BH3O3 Organometallic Reagents Boronic Acids Boronic Acids and Derivatives Aryl Substituted Boronic Acids Alkoxy Aryl Organoborons blocks BoronicAcids Boronic Acid series Boronic Acid B (Classes of Boron Compounds) Boronic Acids Boronic Acids Boronic Acids and Derivatives