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4-Aminoveratrole

4-Aminoveratrole Structure
4-Aminoveratrole structure
CAS No.
6315-89-5
Chemical Name:
4-Aminoveratrole
Synonyms
3,4-DIMETHOXYANILINE;25kg;100G/500G/25KG;4-AMINOVERATROL;4-AMINOVERATROLE;3,4-DimethoxyaniL;TIMTEC-BB SBB004043;13,4-MethoxyAniline;3,4-dimethoxy-anilin;4-Aminoveratrole,98%
CBNumber:
CB9694299
Molecular Formula:
C8H11NO2
Molecular Weight:
153.18
MDL Number:
MFCD00008394
MOL File:
6315-89-5.mol
MSDS File:
SDS
Last updated:2026-05-28 05:44:39
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4-Aminoveratrole Properties

Melting point 85-89 °C (lit.)
Boiling point 174-176 °C/22 mmHg (lit.)
Density 1.1577 (rough estimate)
refractive index 1.4640 (estimate)
Flash point 174-176°C/22mm
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Chloroform (Sparingly), Methanol (Slightly)
pka 4.78±0.10(Predicted)
form Crystalline Powder
color Brown
Water Solubility insoluble
BRN 743399
InChI 1S/C8H11NO2/c1-10-7-4-3-6(9)5-8(7)11-2/h3-5H,9H2,1-2H3
InChIKey LGDHZCLREKIGKJ-UHFFFAOYSA-N
SMILES COc1ccc(N)cc1OC
CAS DataBase Reference 6315-89-5(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII XD9UJ596XD
NIST Chemistry Reference Benzenamine, 3,4-dimethoxy-(6315-89-5)
EPA Substance Registry System 3,4-Dimethoxyaniline (6315-89-5)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312
Precautionary statements  P280-P301+P312+P330-P302+P352+P312
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn,T,Xi
Risk Statements  22-36/37/38-20/21/22
Safety Statements  22-24/25-36/37/39-26-36
RIDADR  2811
WGK Germany  3
RTECS  BX4550000
Hazard Note  Toxic/Irritant
TSCA  TSCA listed
HazardClass  6.1(b)
PackingGroup  III
HS Code  29222900
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Dermal
Acute Tox. 4 Oral
NFPA 704
1
2 0

4-Aminoveratrole price More Price(67)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A83008 3,4-Dimethoxyaniline 98% 6315-89-5 10g $90.6 2026-04-30 Buy
Sigma-Aldrich A83008 3,4-Dimethoxyaniline 98% 6315-89-5 25g $178 2023-06-20 Buy
TCI Chemical D1485 3,4-Dimethoxyaniline >98.0%(GC)(T) 6315-89-5 25g $32 2026-04-30 Buy
TCI Chemical D1485 3,4-Dimethoxyaniline >98.0%(GC)(T) 6315-89-5 500g $314 2026-04-30 Buy
TRC TRC-D470605-50G 3,4-Dimethoxyaniline 6315-89-5 50g $231 2026-06-03 Buy
Product number Packaging Price Buy
A83008 10g $90.6 Buy
A83008 25g $178 Buy
D1485 25g $32 Buy
D1485 500g $314 Buy
TRC-D470605-50G 50g $231 Buy

4-Aminoveratrole Chemical Properties, Uses, Production

Chemical Properties

BROWN CRYSTALLINE POWDER

Uses

3,4-Dimethoxyaniline is commonly used as fine chemicals, used for pharmaceutical intermediates.

Synthesis Reference(s)

Tetrahedron Letters, 27, p. 4687, 1986 DOI: 10.1016/S0040-4039(00)85038-8

Synthesis

(1) Put 5000kg of methanol and 1250kg of 3,4-dimethoxynitrobenzene into the chemical kettle, and the subsequent feeding was carried out in accordance with the ratio, stirred well, pumped into the first-stage hydrogenation kettle, added 125kg of Pd/Al2O3 catalyst, with the particle size of catalyst of 10nm, passed into nitrogen replacement system for three times, and then passed into the hydrogen replacement system for three times, and turned on the stirring, and the temperature was raised to 90-100. Temperature rise to 90-100 , with a flow rate of 6000L / h to the first hydrogenation kettle pumped into the 3,4-dimethoxynitrobenzene feedstock liquid, through the H2, the control system of hydrogen pressure of 1.0MPa, and every 3h interval to the first hydrogenation kettle to supplement the addition of Pd / Al2O3 catalyst 2.5kg, the first hydrogenation kettle of the gradual increase in the material through the overflow port into the secondary After gradually increasing the material in the first hydrogenation kettle, it will flow into the second hydrogenation kettle through the overflow port, and the material will stay in the hydrogenation kettle for about 2-3h, and the reaction will be qualified (with the residual amount of 3,4-dimethoxynitrobenzene 0.2%), then it will overflow to the settlement kettle through the second hydrogenation kettle.

(2) The material is settled in the settling kettle, the lower catalyst is pumped into the hydrogenation kettle, the upper reducing solution is pumped into the membrane filtration system, the two membrane filters are connected in series, and the pump realizes the internal recycling, and the catalyst in the reducing solution is gradually concentrated to 10-30%, and the pump pumps the concentrated catalyst material into the catalyst charging tank to realize the internal recycling. The membrane used in this step is a ceramic membrane with an average pore size of 2 nm.

(3) After filtration of the reducing solution, it goes into a distillation kettle, and after warming up to remove the solvent methanol, the feed solution is put into a crystallization kettle, and after purification, the product of 3,4-dimethoxyaniline is obtained with a content of 99.9% and a production capacity of 950 kg/h.

4-Aminoveratrole synthesis

709-09-1
6315-89-5
Synthesis of 4-Aminoveratrole from 3,4-Dimethoxynitrobenzene

4-Aminoveratrole Preparation Products And Raw materials

Raw materials

4-azido-1,2-dimethoxybenzene Benzamide, N-hydroxy-3,4-dimethoxy- 3,4-Dimethoxyphenol veratrylglycerol-beta-guaiacyl ether 3,4-Dimethoxynitrobenzene
4-Bromoveratrole 3,4-Dimethoxyacetophenone 4-chloro-1,2-dimethoxy-benzene 1,2-Dimethoxybenzene

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Preparation Products

4-chloro-6,7-dimethoxyquinoline 4-Aminocatechol 2,3-Dimethoxyaniline 2'-Amino-4',5'-dimethoxyacetophenone Benzenediazonium, 4,5-dimethoxy-2-[[4-nitro-2-(phenylsulfonyl)phenyl]azo]-
6,7-Dimethoxy-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester

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4-Aminoveratrole Suppliers

Global Suppliers ( 394)
Supplier Tel Email Country ProdList Advantage
shanghai huiyu 15380804498 hj.yang@nstbio.com China 293 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
future industrial shanghai co., ltd 400-0066400 13621662912 sales@jonln.com China 1989 65
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
ShangHai DEMO Chemical Co.,Ltd 400-021-7337 2355568890 sales@demochem.com China 2569 57
Beijing dtftchem Technology Co., Ltd. 010-60275820 13031183356 elainezt@sina.com China 1386 62
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Supplier Advantage
shanghai huiyu 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
future industrial shanghai co., ltd 65
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
ShangHai DEMO Chemical Co.,Ltd 57
Beijing dtftchem Technology Co., Ltd. 62
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56

View Latest Price from 4-Aminoveratrole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Aminoveratrole pictures 2026-06-30 4-Aminoveratrole
6315-89-5
 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
4-Aminoveratrole pictures 2026-05-28 4-Aminoveratrole
6315-89-5
 $10.00-30.00 10kg 99% 100000kg Hebei Chuanghai Biotechnology Co,.LTD
4-Aminoveratrole pictures 2026-03-20 4-Aminoveratrole
6315-89-5
 $10.00 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd

4-Aminoveratrole Spectrum

4-Aminoveratrole(6315-89-5)MS4-Aminoveratrole(6315-89-5)1HNMR4-Aminoveratrole(6315-89-5)13CNMR4-Aminoveratrole(6315-89-5)IR14-Aminoveratrole(6315-89-5)IR24-Aminoveratrole(6315-89-5)Raman

6315-89-5 (4-Aminoveratrole) Related Search:

4-(Trifluoromethoxy)aniline Dimethyldimethoxysilane Diphenyldimethoxysilane 1,1-Dimethoxyethane Phenetidine
p-Anisidine m-Anisidine Cyclopropanecarboxylic acid, 1-[[(2-fluorophenyl)amino]carbonyl]- Cabozantinib impurity 1DYH 1,1-Cyclopropanedicarboxamide, N,N'-bis[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-
Cabozantinib Malate Cyclopropanecarboxylic acid, 1-[(phenylaMino)carbonyl]- Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)- 1,1-Cyclopropanedicarboxamide,N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-phenyl- Cyclopropanecarboxylic acid, 1-[[[4-[[7-methoxy-6-(sulfooxy)-4-quinolinyl]oxy]phenyl]amino]carbonyl]-
1-((4-Fluorophenyl)carbamoyl)cyclopropanecarboxylic acid Cabozantinib impurity DX2 Cabozantinib Impurity EXA

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2-Methoxy-4-aminoanisole 3,4-dimethoxy-anilin 3,4-Dimethoxyaniline(4-Aminoveratrole) 3,4-dimethoxy-benzenamin 3,4-dimethoxybenzenamine Aniline, 3,4-dimethoxy- 4-AMINOVERATROL 4-AMINOVERATROLE 4-AMINOPYROCATECHOL DIMETHYL ETHER 4-AMINOPYROCATECHOL DIMETHYL ETHER 4-AMINOVERATROLE 3,4-DIMETHYLOXY ANILINE 3,4-DimethoxyaniL 1,2-dimethoxy-4-aminobenzene TIMTEC-BB SBB004043 3,4-Dimethoxyaniline, 98+% 4-AMINOCATECHOLDIMETHYLETHER Benzenamine, 3,4-dimethoxy- 4-Aminoveratrole,98% 100G/500G/25KG 3,4-Bis(Methoxy)aniline Aniline, 3,4-diMethoxy- (7CI,8CI) 3,4- twoMethoxyaniline 4-AMinoveratrole, 98% 10GR 3,4-Dimethoxyaniline > 3,4-Dimethoxy Aniline (3,4-DMA) 25kg 3,4-DIMETHOXYANILINE 13,4-MethoxyAniline 6315-89-5 6315-85-9 6375-89-5 C8H11O2N H2NC6H3OCH32 Nitrogen Compounds Organic Building Blocks Building Blocks Amines C8 Anilines, Aromatic Amines and Nitro Compounds Amines and Anilines bc0001