N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl)
- CAS No.
- 2112737-71-8
- Chemical Name:
- N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl)
- Synonyms
- N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl);Ethanamine, 2-[2-[2-(aminooxy)ethoxy]ethoxy]-N,N-bis[2-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]ethyl]-
- CBNumber:
- CB73373669
- Molecular Formula:
- C24H44N2O9
- Molecular Weight:
- 504.61
- MDL Number:
- MFCD30828701
- MOL File:
- 2112737-71-8.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501 |
N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0115210 | N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) ≥95% | 2112737-71-8 | 50mg | $165 | 2026-06-04 | Buy |
| ChemScene | CS-0115210 | N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) ≥95% | 2112737-71-8 | 100mg | $255 | 2026-06-04 | Buy |
| ChemScene | CS-0115210 | N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) ≥95% | 2112737-71-8 | 250mg | $504 | 2026-06-04 | Buy |
| BroadPharm | bp-23651 | N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) 98% | 2112737-71-8 | 100MG | $350 | 2026-05-24 | Buy |
| BroadPharm | bp-23651 | N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) 98% | 2112737-71-8 | 250MG | $680 | 2026-05-24 | Buy |
N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) Chemical Properties, Uses, Production
Description
N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) consists of two terminal propargyl groups and an aminooxy group. The propargyl groups reacts with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry. The aminooxy group is reactive towards aldehydes to form oxime bonds. If a reductant is used, it will form a hydroxylamine linkage. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended.
Uses
N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) Preparation Products And Raw materials
Raw materials
Preparation Products
N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 54996 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 770406999@qq.com | China | 9949 | 58 |
| Shanghai Huici Pharmaceutical Technology Co., LTD | 133-31922809 19372841038 | lixing@pharmahuici.com | China | 853 | 58 |
| Affinity（Wuhan）Ltd. | 15841022315 | sales@affinitytech.cn | China | 2982 | 58 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80514535 19917294565 | et@chemextension.com | China | 5061 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Henan Alpha Chemical Co., Ltd. | 0371-55013243 15324716602 | 2232176231@qq.com | China | 9996 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 17801761073 | Gsiyu@solarbio.com | China | 50460 | 58 |
View Latest Price from N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-15 | N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl)
2112737-71-8
|
$39.00-61.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2025-06-07 | N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl)
2112737-71-8
|
250mg | >95.00% | 250mg | Xian confluore Biological Technology Co., Ltd. |
-
- N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl)
2112737-71-8
- $39.00-61.00
- TargetMol Chemicals Inc.
-
- N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl)
2112737-71-8
- $0.00
- >95.00%
- Xian confluore Biological Technology Co., Ltd.
