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2-(methylthio)pyrimidine-4,6-diol

2-(methylthio)pyrimidine-4,6-diol Structure
2-(methylthio)pyrimidine-4,6-diol structure
CAS No.
1979-98-2
Chemical Name:
2-(methylthio)pyrimidine-4,6-diol
Synonyms
4,6-DIHYDROXY-2-METHYLTHIOPYRIMIDINE;S-MTBA;NSC 44557;2-Methylthio-4;1Drug Likeness;6-pyriMidinedione;2-Methylthio-4,6-pyr;S-METHYLTHIOBARBITURIC ACID;2-Methylthiobarbituric acid;2-Mercapto thobarbituric acid
CBNumber:
CB7345836
Molecular Formula:
C5H6N2O2S
Molecular Weight:
158.18
MDL Number:
MFCD00006087
MOL File:
1979-98-2.mol
MSDS File:
SDS
Last updated:2026-05-28 05:26:17
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2-(methylthio)pyrimidine-4,6-diol Properties

Melting point >300 °C(lit.)
Density 1.55±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Ethyl Acetate, Ethanol, Methanol
form Powder
pka 4.06±0.10(Predicted)
color White
CAS DataBase Reference 1979-98-2(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Safety Statements  22-24/25
WGK Germany  2
HS Code  29339900
NFPA 704
1
2 0

2-(methylthio)pyrimidine-4,6-diol price More Price(58)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological M3541-78 2-(Methylthio)-4,6-pyrimidinediol 1979-98-2 250mg $312 2026-06-03 Buy
Usbiological M3541-78 2-(Methylthio)-4,6-pyrimidinediol 1979-98-2 2.5g $389 2026-06-03 Buy
Usbiological M3541-78 2-(Methylthio)-4,6-pyrimidinediol 1979-98-2 5g $475 2026-06-03 Buy
Usbiological M3541-78 2-(Methylthio)-4,6-pyrimidinediol 1979-98-2 25g $736 2026-06-03 Buy
Usbiological 281704 2-Methylthio-4,6-dihydroxypyrimidine Asreported 1979-98-2 25g $319 2026-06-03 Buy
Product number Packaging Price Buy
M3541-78 250mg $312 Buy
M3541-78 2.5g $389 Buy
M3541-78 5g $475 Buy
M3541-78 25g $736 Buy
281704 25g $319 Buy

2-(methylthio)pyrimidine-4,6-diol Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

2-(Methylthio)-4,6-pyrimidinediol (cas# 1979-98-2) is a compound useful in organic synthesis.

Synthesis

2-Thiobarbituric acid

504-17-6

Iodomethane

74-88-4

2-(methylthio)pyrimidine-4,6-diol

1979-98-2

Step a: Synthesis of 2-methylthio-pyrimidine-4,6-diol (19a); Iodomethane (32.64 g, 220 mmol) was slowly added dropwise to a suspension of thiobarbituric acid (29 g, 200 mmol) dissolved in ethanol (300 mL) and 2M aqueous sodium hydroxide (110 mL) at room temperature. The reaction mixture was stirred overnight at room temperature, followed by warming to 60 °C and continued stirring for 2 hours. Upon completion of the reaction, ethanol was removed by distillation under reduced pressure, an appropriate amount of water was added and the mixture was cooled in an ice bath for 2 hours. The precipitated solid 4,6-dihydroxy-2-methylmercaptopyrimidine was collected by filtration, washed with ice water and dried to give the product (30 g, 95% yield).

References

[1] Patent: WO2008/95999, 2008, A1. Location in patent: Page/Page column 96
[2] Patent: WO2012/97478, 2012, A1. Location in patent: Page/Page column 58-59

2-(methylthio)pyrimidine-4,6-diol Preparation Products And Raw materials

Raw materials

4,6-Dihydroxypyrimidine 2-Thiobarbituric acid Iodomethane Water Ethanol
Sodium hydroxide

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Preparation Products

4,6-Dimethoxypyrimidine-2-sulfonyl chloride 4,6-Dichloro-2-(methylthio)pyrimidine-5-carbonitrile

2-(methylthio)pyrimidine-4,6-diol Suppliers

Global( 287)Suppliers
Supplier Tel Email Country ProdList Advantage
Wuhan Hongde Yuexin Pharmaceutical Technology Co., Ltd 02783850058 15377551550 whhdyxchem027@sina.com China 999 58
Shanghai Boyle Chemical Co., Ltd. 021-50182298 021-50180596 sales@boylechem.com China 2202 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
ShangHai DEMO Chemical Co.,Ltd 400-021-7337 2355568890 sales@demochem.com China 2569 57
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Supplier Advantage
Wuhan Hongde Yuexin Pharmaceutical Technology Co., Ltd 58
Shanghai Boyle Chemical Co., Ltd. 55
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Alfa Aesar 84
TAIYUAN RHF CO.,LTD. 56
TCI (Shanghai) Development Co., Ltd. 81
ShangHai DEMO Chemical Co.,Ltd 57
Beijing HwrkChemical Technology Co., Ltd 55
Energy Chemical 61

View Lastest Price from 2-(methylthio)pyrimidine-4,6-diol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Methylthio-4,6-pyrimidinedione pictures 2025-06-25 2-Methylthio-4,6-pyrimidinedione
1979-98-2
 $1.10 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd
2-(methylthio)pyrimidine-4,6-diol pictures 2025-05-23 2-(methylthio)pyrimidine-4,6-diol
1979-98-2
 $50.00-100.00 1kg 99% 20 tons Hebei Zhuanglai Chemical Trading Co Ltd
2-Methylthio-4,6-pyrimidinedione pictures 2025-04-04 2-Methylthio-4,6-pyrimidinedione
1979-98-2
 1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.

2-(methylthio)pyrimidine-4,6-diol Spectrum

2-Methylthio-4,6-pyrimidinedione(1979-98-2)MS2-Methylthio-4,6-pyrimidinedione(1979-98-2)1HNMR2-Methylthio-4,6-pyrimidinedione(1979-98-2)13CNMR2-Methylthio-4,6-pyrimidinedione(1979-98-2)IR12-Methylthio-4,6-pyrimidinedione(1979-98-2)IR22-Methylthio-4,6-pyrimidinedione(1979-98-2)Raman

1979-98-2(2-(methylthio)pyrimidine-4,6-diol)Related Search:

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4-Hydroxy-2-(methylthio)pyrimidin-6(1H)-one, 4,6-Dihydroxy-2-(methylthio)pyrimidine, 2-(Methylsulphanyl)pyrimidine-4,6-diol 6-Hydroxy-2-(methylthio)pyrimidin-4(3H)-one 6-Hydroxy-2-(Methylthio)-4-pyriMidinone NSC 44557 2-Methylthio-4,6-pyriMidinedione, 95+% S-MTBA S-METHYLTHIOBARBITURIC ACID 2-(Methylmercapto)-4,6-pyrimidinediol 4,6-dihydroxy-2-methylmercaprimidine 2-Mercapto thobarbituric acid 4,6-dihydroxyl-2-methylthio-pyrimidine 2-Thiomethyl 4,6-Dihydroxy Pyrimidine DIHYDROXY-2-METHYLMERCAPTOPYRIMIDINE 2-Methylthiobarbituric acid 4(1H)-PYRIMIDINONE, 6-HYDROXY-2-(METHYLTHIO)- 2-METHYLTHIO-4,6-PYRIMIDINEDIOL 2-Methylthio-4,6-pyrimidinedione 6-Hydroxy-2-(methylthio)pyrimidin-4(3H)-one 95+% 2-(Methylmercapto)-4,6-Pyrimid 2-methylthio-4,6-dihydroxylpyrimidine 2-Methylthiopyrimidin-4,6-diol 4,6-Dihydroxy-2-(methylmercapto)pyrimidine 6-Hydroxy-2-methylthio-4(3H)-pyrimidinone, 97% 4，6-dihydroxy-2-methyl metcapto pyrimidine 4,6-Dihydroxy-2-(methylmercapto)pyrimidine, 4,6-Dihydroxy-2-(methylthio)pyrimidine 2-Methylthio-4,6-pyrimidinedione ,98% 6-Hydroxy-2-(methylthio)pyrimidin-4(1H)-one 6-Hydroxy-2-(methylthio)-4(1H)-pyrimidinone 4-hydroxy-2-(methylthio)-1H-pyrimidin-6-one 4-hydroxy-2-methylsulfanyl-1H-pyrimidin-6-one 2-Methylthio-4,6-pyr 2-Methylthio-4 6-pyriMidinedione S-MethylthiobarbituricAcid> 4(3H)-Pyrimidinone, 6-hydroxy-2-(methylthio)- 1Drug Likeness 2-Methylthio-4,6-pyrimidinedione ISO 9001：2015 REACH 2-Methylthio-5-fluoro-4,6-dihydroxypyrimidine 2-(Methylthio)pyrimidine-4,6-diol 4,6-DIHYDROXY-2-METHYLTHIOPYRIMIDINE https://www.chemicalbook.com/ProdSupplierGNCB7345836.htm 1979-98-2 Building Blocks Pyrimidines Heterocyclic Building Blocks Pyrimidine Bases & Related Reagents Nucleotides Sulfur & Selenium Compounds Nucleotides and Nucleosides Pyrimidines Heterocycle-Pyrimidine series