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4-Hydroxypyrimidine

CAS No.
51953-17-4
Chemical Name:
4-Hydroxypyrimidine
Synonyms
4(1H)-PYRIMIDINONE;4(3H)-PYRIMIDINONE;4-PYRIMIDONE;4-PYRIMIDINONE;4(3H)-PYRIMIDONE;3H-pyrimidin-4-one;4-HYDROXYPYRIMIDINE;4(3H)-pyrimidineone;4(6)-HYDROXYPYRIMIDINE;4(3H)-PYRIMIDONE, 98+%
CBNumber:
CB5117293
Molecular Formula:
C4H4N2O
Molecular Weight:
96.09
MDL Number:
MFCD00167178
MOL File:
51953-17-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-08-28 09:47:36

4-Hydroxypyrimidine Properties

Melting point 166-169 °C(lit.)
Boiling point 179.58°C (rough estimate)
Density 1.2604 (rough estimate)
refractive index 1.4610 (estimate)
storage temp. 0-6°C
pka pK1:1.85(+1);pK2:8.59(0) (25°C)
form Powder
color White to slightly yellow
Water Solubility 270.3g/L(20 ºC)
BRN 106975
InChI InChI=1S/C4H4N2O/c7-4-1-2-5-3-6-4/h1-3H,(H,5,6,7)
InChIKey DNCYBUMDUBHIJZ-UHFFFAOYSA-N
SMILES C1(=O)N=CNC=C1
CAS DataBase Reference 51953-17-4(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII K43V90OY4L

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25-37/39-26-36
WGK Germany  3
RTECS  UW7350100
TSCA  Yes
HS Code  29339900
NFPA 704
1
2 0

4-Hydroxypyrimidine price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FP57999 4(3H)-Pyrimidone 51953-17-4 10g $150 2026-06-04 Buy
Biosynth FP57999 4(3H)-Pyrimidone 51953-17-4 100g $150 2026-06-04 Buy
Biosynth FP57999 4(3H)-Pyrimidone 51953-17-4 50g $150 2026-06-04 Buy
Biosynth FP57999 4(3H)-Pyrimidone 51953-17-4 250g $300 2026-06-04 Buy
aablocks AA003LH3 4(3H)-Pyrimidone 98% 51953-17-4 1g $19 2026-05-28 Buy
Product number Packaging Price Buy
FP57999 10g $150 Buy
FP57999 100g $150 Buy
FP57999 50g $150 Buy
FP57999 250g $300 Buy
AA003LH3 1g $19 Buy

4-Hydroxypyrimidine Chemical Properties,Uses,Production

Description

Pyrimidone(4-Hydroxypyrimidine) is the name given to either of two heterocyclic compounds with the formula C4H4N2O: 2-pyrimidone and 4-pyrimidone. The compounds can also be called 2-hydroxypyrimidine or 4-hydroxypyrimidine respectively, based on a substituted pyrimidine, or 1, 3-diazine, ring. 4-pyrimidinone is an important bioactive molecule with various biological activities such as anti-virus, anti-tumor, induction of interferon production and immune regulation.

Chemical Properties

white to slightly yellow powder

Uses

4(3H)-pyrimidinone heterocyclic compounds and their pharmaceutically usable salts can be used to treat and/or prevent SHP2-mediated conditions, particularly in cancer clinical drug research. Furthermore, based on a series of studies on 4(3H)-pyrimidinones and their derivatives (such as 4-Hydroxypyrimidine), some substances have been found to act as modulators of the TRPV4 receptor, exhibiting promising properties in the treatment of various diseases and syndromes, especially in the treatment of inflammatory, painful, and urinary disorders and dysregulation.

Hazard

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Enzyme inhibitor

This hygroscopic pyrimidine, also known as 4-hydroxypyrimidine and 4- pyrimidinol (FW = 96.09 g/mol), inhibits both hypoxanthine(guanine) and xanthine phosphoribosyltransferases.

Global( 153)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
China DongFan Chemical Co.,LTD 86-0571-85151182 China 5681 66
Jinan Trio PharmaTech Co., Ltd. 0531-88811783 sales@trio-pharmatech.com China 1856 62

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View Lastest Price from 4-Hydroxypyrimidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Hydroxypyrimidine  pictures 2026-08-20 4-Hydroxypyrimidine
51953-17-4
$1.10 1g 99.00% 100 Tons Dideu Industries Group Limited
4-Hydroxypyrimidine pictures 2020-01-13 4-Hydroxypyrimidine
51953-17-4
$1.00 1KG 99% 100KG Career Henan Chemical Co
3,4-dihydropyriMidin-4-one 4(3H)-PyriMidone, 98+% 10GR 4(3H)-PyriMidinone, 98+% 4(3H)-PYRIMIDONE 4-PYRIMIDINONE 4-PYRIMIDONE 4(6)-HYDROXYPYRIMIDINE 4-HYDROXYPYRIMIDINE 3H-pyrimidin-4-one 4(3H)-PYRIMIDONE, 98+% 4(3H)-Pyrimidinone (9CI) 4-HYDROXYPYRIMIDINE 98% 4-Hydroxypyrimidine ISO 9001:2015 REACH 4(3H)-pyrimidineone 4(1H)-PYRIMIDINONE 4(3H)-PYRIMIDINONE 51953-17-4 4652-27-0 C4H4N2O Heterocyclic Building Blocks Pyrimidines Building Blocks PYRIMIDINE Heterocycles Building Blocks Heterocyclic Building Blocks Pyrimidines Pyrimidine series