1-Boc-piperidine
- CAS No.
- 75844-69-8
- Chemical Name:
- 1-Boc-piperidine
- Synonyms
- 1-BOC-PIPERIDINE;N-BOC-PIPERIDINE;1-Boc-Piperidine,98%;N-Boc-tetrahydropyridine;1-(tert-Butoxycarbonyl)piperidine;N-(TERT-BUTOXYCARBONYL)PIPERIDINE;tert-Butyl 1-piperidinecarboxylate;1-(tert-Butyloxycarbonyl)piperidine;tert-butyl piperidine-1-carboxylate;1-(tert-Butoxycarbonyl)piperidine >
- CBNumber:
- CB7348312
- Molecular Formula:
- C10H19NO2
- Molecular Weight:
- 185.26
- MDL Number:
- MFCD02093935
- MOL File:
- 75844-69-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1-(tert-Butoxycarbonyl)piperidine >98.0%(GC) | B4625 | 5g | $43 |
| 1-(tert-Butoxycarbonyl)piperidine >98.0%(GC) | B4625 | 25g | $142 |
| 1-BOC-Piperidine | B662033 | 500mg | $75 |
| tert-Butyl piperidine-1-carboxylate | FB142536 | 10g | $80 |
| tert-Butyl piperidine-1-carboxylate | 4H56-1-FU | 5G | $75 |
| More product size | |||
| Boiling point | 130-140°C 15mm |
|---|---|
| Density | 0.964 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 188 °F |
| storage temp. | Sealed in dry,Room Temperature |
| pka | -1.28±0.20(Predicted) |
| form | Liquid |
| color | Clear colorless to pale yellow |
| BRN | 3604898 |
| CAS DataBase Reference | 75844-69-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H315-H319-H335-H400-H227 | |||||||||
| Precautionary statements | P210e-P280a-P370+P378a-P403+P235-P501a-P261-P273-P301+P310-P305+P351+P338 | |||||||||
| Hazard Codes | T,N,Xi | |||||||||
| Risk Statements | 25-36/37/38-50 | |||||||||
| Safety Statements | 26-36-45-60-61 | |||||||||
| RIDADR | UN 2810 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT, KEEP COLD | |||||||||
| PackingGroup | Ⅲ | |||||||||
| HS Code | 29333990 | |||||||||
| NFPA 704 |
|
1-Boc-piperidine price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B4625 | 1-(tert-Butoxycarbonyl)piperidine >98.0%(GC) | 75844-69-8 | 5g | $43 | 2025-07-31 | Buy |
| TCI Chemical | B4625 | 1-(tert-Butoxycarbonyl)piperidine >98.0%(GC) | 75844-69-8 | 25g | $142 | 2025-07-31 | Buy |
| TRC | B662033 | 1-BOC-Piperidine | 75844-69-8 | 500mg | $75 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB142536 | tert-Butyl piperidine-1-carboxylate | 75844-69-8 | 10g | $80 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4H56-1-FU | tert-Butyl piperidine-1-carboxylate | 75844-69-8 | 5G | $75 | 2021-12-16 | Buy |
1-Boc-piperidine Chemical Properties,Uses,Production
Chemical Properties
Colorless liquid
Synthesis
110-89-4
24424-99-5
75844-69-8
The general procedure for the synthesis of tert-butyl piperidine-1-carboxylate from hexahydropyridine and di-tert-butyl dicarbonate is as follows: hexahydropyridine (1 mmol) was added to a solution of ethanol (1 mL) containing magnetically stirred guanidine hydrochloride (15 mol%) and di-tert-butyl dicarbonate (1.2 mmol) and the reaction was stirred to completion at 35-40 °C (reaction progress was monitored by TLC or GC). Upon completion of the reaction, the ethanol is evaporated under vacuum and the residue is washed with water to remove the catalyst or dissolved in dichloromethane (or ethyl acetate) and filtered to separate the catalyst. If an organic solvent is used for post-treatment, the product is almost pure after evaporation of the organic solvent. If excess di-tert-butyl dicarbonate is used, the product can be washed with petroleum ether or hexane to recover the residual di-tert-butyl dicarbonate. If necessary, the product can be further purified by crystallization (using hexane and dichloromethane, or ether and petroleum ether as solvents) or silica gel column chromatography (ethyl acetate-hexane (1:6) as eluent).
References
[1] Synthesis, 2006, # 16, p. 2784 - 2788
[2] Tetrahedron Letters, 2007, vol. 48, # 47, p. 8318 - 8322
[3] Tetrahedron Letters, 2008, vol. 49, # 16, p. 2527 - 2532
[4] Tetrahedron Letters, 2011, vol. 52, # 12, p. 1260 - 1264
[5] Monatshefte fur Chemie, 2011, vol. 142, # 10, p. 1035 - 1043
1-Boc-piperidine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12373 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| GLR Innovations | +91 9891111994 | info@glrgroup.in | India | 4535 | 58 |
| Sichuan Biosynce Pharmatech Co., Ltd. | +8619950309693 | diane@biosynce.com | China | 4871 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33325 | 58 |
| Suzhou ARTK Medchem Co., Ltd. | +86-512-68323658 +86-18168183658 | sales1@artkmedchem.com | China | 39002 | 58 |
View Lastest Price from 1-Boc-piperidine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-03 | 1-Boc-piperidine
75844-69-8
|
US $1.00 / KG | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- 1-Boc-piperidine
75844-69-8
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
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