Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>N-BOC-4-Hydroxypiperidine

N-BOC-4-Hydroxypiperidine

N-BOC-4-Hydroxypiperidine Structure
N-BOC-4-Hydroxypiperidine structure
CAS No.
109384-19-2
Chemical Name:
N-BOC-4-Hydroxypiperidine
Synonyms
TERT-BUTYL 4-HYDROXYPIPERIDINE-1-CARBOXYLATE;1-BOC-4-HYDROXYPIPERIDINE;4-HYDROXY-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;N-BOC-4-PIPERIDINOL;N-(TERT-BUTOXYCARBONYL)-4-PIPERIDINOL;1-(TERT-BUTOXYCARBONYL)-4-HYDROXYPIPERIDINE;TERT-BUTYL 4-HYDROXY-1-PIPERIDINECARBOXYLATE;Boc-4-piperidinol;1-Bocpiperidin-4-ol;RARECHEM AH CK 0055
CBNumber:
CB7382529
Molecular Formula:
C10H19NO3
Molecular Weight:
201.26
MDL Number:
MFCD01075174
MOL File:
109384-19-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:31:10
Request For Quotation

N-BOC-4-Hydroxypiperidine Properties

Melting point 61-65 °C (lit.)
Boiling point 292.3±33.0 °C(Predicted)
Density 1.107±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform, Ethyl Acetate
pka 14.80±0.20(Predicted)
form Powder
color White to cream
BRN 7202094
InChI InChI=1S/C10H19NO3/c1-10(2,3)14-9(13)11-6-4-8(12)5-7-11/h8,12H,4-7H2,1-3H3
InChIKey PWQLFIKTGRINFF-UHFFFAOYSA-N
SMILES N1(C(OC(C)(C)C)=O)CCC(O)CC1
CAS DataBase Reference 109384-19-2(CAS DataBase Reference)
UNSPSC Code 12352005
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
HazardClass  IRRITANT
HS Code  29339900
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

N-BOC-4-Hydroxypiperidine price More Price(108)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 495484 1-Boc-4-hydroxypiperidine 97% 109384-19-2 5g $65.4 2026-04-30 Buy
Sigma-Aldrich 495484 1-Boc-4-hydroxypiperidine 97% 109384-19-2 25g $139 2026-04-30 Buy
TCI Chemical B2671 1-(tert-Butoxycarbonyl)-4-hydroxypiperidine >97.0%(GC) 109384-19-2 5g $17 2026-04-30 Buy
TCI Chemical B2671 1-(tert-Butoxycarbonyl)-4-hydroxypiperidine >97.0%(GC) 109384-19-2 25g $40 2026-04-30 Buy
Usbiological 261897 1-Boc-4-piperidinol 109384-19-2 25g $306 2026-06-03 Buy
Product number Packaging Price Buy
495484 5g $65.4 Buy
495484 25g $139 Buy
B2671 5g $17 Buy
B2671 25g $40 Buy
261897 25g $306 Buy

N-BOC-4-Hydroxypiperidine Chemical Properties, Uses, Production

Chemical Properties

White to cream powder

Uses

N-Boc-4-hydroxypiperidine is a 4-hydroxypyridine with a boc protecting group used in the preparation of neurologically active agents and other pharmaceutical compounds.

Uses

Used in a synthesis of N-heterocyclic alkyl ethers via the Mitsunobu reaction.

Preparation

A mixture of 4-hydroxypiperidine (10.0 g, 98. 9 mmol), aqueous sodiumhydrogen carbonate (150 mL, 1 M), DI-FERT-BUTYL dicarbonate (21. 6 g, 98.9 mmol) and dichloromethane was stirred for 15 h. The phases were separated and the product (N-BOC-4-Hydroxypiperidine) was isolated as an oil in quantitative yield (19.9 g).
N-BOC-4-Hydroxypiperidine

N-BOC-4-Hydroxypiperidine synthesis

79099-07-3
109384-19-2
Synthesis of N-BOC-4-Hydroxypiperidine from N-(tert-Butoxycarbonyl)-4-piperidone

N-BOC-4-Hydroxypiperidine Preparation Products And Raw materials

Raw materials

Preparation Products

4-Amino-1-Boc-piperidine 1-Boc-4-methanesulfonyloxypiperidine Piperidine, 4-(1H-pyrazol-1-yl)- (9CI) N-Boc-3-hydroxy-1,2,3,6-tetrahydropyridine 4-Phenoxypiperidine
Sar-407899 MK8245 4-(Toluene-4-sulfonyloxy)-piperidine-1-carboxylic acid tert-butyl ester 4-Hydroxypiperidine hydrochloride 4-Methoxypiperidine
Triethylamine hydrochloride 1N-Boc 4-(2'-methyl-4'-nitrophenoxy) piperidine 1-Boc-4-(2-pyridyloxy)piperidine

1of3

Related articles

N-BOC-4-Hydroxypiperidine Spectrum

N-BOC-4-Hydroxypiperidine(109384-19-2)1HNMRN-BOC-4-Hydroxypiperidine(109384-19-2)FT-IR

109384-19-2 (N-BOC-4-Hydroxypiperidine) Related Search:

tert-Butyl 4-methylenepiperidine-1-carboxylate N-Boc-4-piperidinemethanol 1-Boc-4-cyanopiperidine Haloperidol N-Carbobenzyloxyglycine
tert-Butyl peroxyacetate Triacetonediamine tert-Butyl acetate 4-Cyanophenol DROPERIDOL
1-Boc-3-piperidone 2,2,6,6-Tetramethyl-4-piperidinol tert-Butanol Diphenoxylate Carbonyl iron powder
4-Hydroxypiperidine (2R,4S)-N-Boc-4-hydroxypiperidine-2-carboxylic acid methyl ester 1-Boc-4-methanesulfonyloxypiperidine

1of4

1-Boc-4-piperidinol, tert-Butyl 4-hydroxy-1-piperidinecarboxylate N-BOC-4-Hydroxypiperidine,97% 1-Boc-4-hydroxypiperidine ,98% N-Boc-4hydropiperidine 1-(tert-Butoxycarbonyl)-4-hydroxypiperidine, tert-Butyl 4-hydroxypiperidine-1-carboxylate N-Boc-4-hydroxy-1-piperidine tert-butyl 4-hydroxypiperidin-1-carboxylate 1-Boc -4-hydroxypeiperidine 4-Hydroxy-1-(tert-butoxycarbonyl)piperidine N-BOC-4-Hydroxypiperidine, 97% 25GR N-BOC-4-Hydroxypiperidine, 97% 5GR tert-butyl 4-hydro×ypiperidine-1-carbo×ylate N-BOC-4-Hydroxypiper 1-Boc-4-hydroxypiperidine 1-Boc-4-piperidinol 1-(tert-Butyloxycarbonyl)-4-piperidinol 1-Bocpiperidin-4-ol N - bok - 4 - hydroxy piperidine N-BOC-4-Hydroxypiperidine N-(tert-Butoxycarbonyl)-4-hydroxypiperidine t-Butyl 4-hydroxypiperidine-1-carboxylate Boc-(4-hydroxy)piperidine≥ 99% (GC) RARECHEM AH CK 0055 N-(TERT-BUTOXYCARBONYL)-4-HYDROXYPIPERIDINE N-(TERT-BUTOXYCARBONYL)-4-PIPERIDINOL N-BOC-4-HYDROXYPIPERIDINE N-BOC-4-HYDROXYLPIPERIDINE 1-TERT-BUTOXYCARBONYL-4-PIPERIDINOL 1-(TERT-BUTOXYCARBONYL)-4-HYDROXYPIPERIDINE 1-BOC-4-PIPERIDINOL 1-PIPERIDINECARBOXYLIC ACID, 4-HYDROXY-,1,1-DIMETHYLETHYL ESTER BOC-(4-HYDROXY)-PIPERIDINE 1-N-Boc-4-hydroxypiperidine TERT-BUTYL 4-HYDROXY-1-PIPERIDINE-CARBOX Crizotinib Impurity 11 N-BOC-4-Hydroxypiperidine/1-Boc-4-piperidinol 4-Hydroxypiperidine, N-BOC protected 98+% 1-BOC-4-HYDROXYLPIPERIDINE 1-BOC-4-HYDROXYPIPERIDINE / 1-TERT-BUTOXYCARBONYL-4-HYDROXYPIPERIDINE 1-BOC-4-HYDROXY-PIPERIDINE, 1-TERT-BUTOXYCARBONYL-4-HYDROXY-PIPERIDINE 99% 1-BOC-4-HYDROXYPIPERIDINE 99% 4-Hydroxypiperidine, N-BOC protected N-(tert-butyloxycarbonyl)-4-piperidinol (R-TERT-BUTYL 3-(HYDROXYMETHYLPYRROLIDINE-1- 1-(tert-Butoxycarbonyl)-4-hydroxypiperidine > N-Boc-4-Hydroxypiperidine,>98% Ibrutinib Impurity 53 N-tert-Butoxycarbonyl-4-hydroxy piperidine(N-BOC-4H) Ibrutinib Impurity 63 N-Tert.Butoxycarbonyl-4-Hydroxy piperidine (or) N-boc-4-hydroxy piperidine N-BOC-4-Hydroxypiperidinex Boc-4-piperidinol N-BOC-4-Hydroxypiperidine 109384-19-2 Pozitinib intermediate 6 4-Hydroxy-piperidin-1-carboxylic acid tert-butyl ester N-BOC-4-aldehyde piperidine 1-Boc-4-hydroxypiperidine, 99%min N-Boc-4-piperidinol-d4 1-BOC-4-HYDROXYPIPERIDINE 4-HYDROXY-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER