CPPG
- CAS No.
- 183364-82-1
- Chemical Name:
- CPPG
- Synonyms
- CPPG;rac-CPPG;(RS)-CPPG;(RS)-α-Cyclopropyl-4-phosphonophenylglycine;(RS)-ALPHA-CYCLOPROPYL-4-PHOSPHONOPHENYLGLYCINE;(+/-)-ALPHA-CYCLOPROPYL-4-PHOSPHONOPHENYLGLYCINE;Benzeneacetic acid, α-amino-α-cyclopropyl-4-phosphono-;2-Amino-2-cyclopropyl-2-(4-phosphonophenyl)acetic acid;CPPG, group II/III metabotropic glutamate receptor antagonist
- CBNumber:
- CB7356331
- Molecular Formula:
- C11H14NO5P
- Molecular Weight:
- 271.21
- MDL Number:
- MFCD00673967
- MOL File:
- 183364-82-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
CPPG price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0258 | CPPG ≥98% (HPLC) | 183364-82-1 | 5mg | $116 | 2022-05-15 | Buy |
| Sigma-Aldrich | SML0258 | CPPG ≥98% (HPLC) | 183364-82-1 | 25mg | $449 | 2022-05-15 | Buy |
| Cayman Chemical | 34362 | CPPG ≥95% | 183364-82-1 | 1mg | $41 | 2026-04-30 | Buy |
| Cayman Chemical | 34362 | CPPG ≥95% | 183364-82-1 | 5mg | $119 | 2026-04-30 | Buy |
| Cayman Chemical | 34362 | CPPG ≥95% | 183364-82-1 | 10mg | $215 | 2026-04-30 | Buy |
CPPG Chemical Properties,Uses,Production
Uses
(RS)-CPPG is the most potent group II/III mGluR antagonist.
Definition
ChEBI: 2-amino-2-cyclopropyl-2-(4-phosphonophenyl)acetic acid is an alpha-amino acid.
Biological Activity
Potent group II/III mGlu receptor antagonist, with approximately 20-fold selectivity for group III over group II (IC 50 values of 2.2 and 46.2 nM respectively). A much less potent antagonist at group I receptors in neonatal rat cortical slices (K b = 0.65 ± 0.07 nM). Also available as part of the Group III mGlu Receptor Tocriset™ .
IC 50
group III mGlu receptors: 2.2 nM (IC50); group II mGlu receptors: 46.2 nM (IC50)
storage
Room temperature
CPPG Preparation Products And Raw materials
Raw materials
Preparation Products
CPPG Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8435 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai Han-Xiang Chemical Co., Ltd. | 17754423994 | candy@biochempartner.com | China | 3057 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19904 | 58 |
| Jiangsu Hongmin Pharmaceutical Co., Ltd. | 18221292452 | fannieliu@glschina.com | China | 6798 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8137 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
