| Company Name: |
BOC Sciences |
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16314854226; +8616314854226 |
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inquiry@bocsci.com |
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| Product Name: | CPPG | | Synonyms: | CPPG;(+/-)-ALPHA-CYCLOPROPYL-4-PHOSPHONOPHENYLGLYCINE;(RS)-ALPHA-CYCLOPROPYL-4-PHOSPHONOPHENYLGLYCINE;(RS)-CPPG;(RS)-α-Cyclopropyl-4-phosphonophenylglycine;Benzeneacetic acid, α-amino-α-cyclopropyl-4-phosphono-;rac-CPPG;2-Amino-2-cyclopropyl-2-(4-phosphonophenyl)acetic acid | | CAS: | 183364-82-1 | | MF: | C11H14NO5P | | MW: | 271.21 | | EINECS: | | | Product Categories: | Glutamate receptor | | Mol File: | 183364-82-1.mol |  |
| Boiling point | 541.538±60.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.565±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | storage temp. | Store at RT | | solubility | H2O: >5mg/mL | | form | Solid | | pka | 1.546±0.10(predicted) | | color | white to beige |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | 3 |
| Uses | (RS)-CPPG is the most potent group II/III mGluR antagonist. | | Definition | ChEBI: 2-amino-2-cyclopropyl-2-(4-phosphonophenyl)acetic acid is an alpha-amino acid. | | Biological Activity | Potent group II/III mGlu receptor antagonist, with approximately 20-fold selectivity for group III over group II (IC 50 values of 2.2 and 46.2 nM respectively). A much less potent antagonist at group I receptors in neonatal rat cortical slices (K b = 0.65 ± 0.07 nM). Also available as part of the Group III mGlu Receptor Tocriset™ . | | IC 50 | group III mGlu receptors: 2.2 nM (IC50); group II mGlu receptors: 46.2 nM (IC50) | | storage | Room temperature |
| | CPPG Preparation Products And Raw materials |
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