2-Fluoro-6-nitrophenol
- CAS No.
- 1526-17-6
- Chemical Name:
- 2-Fluoro-6-nitrophenol
- Synonyms
- 2-Fluoro-6-nitrophen;2-Fluor-6-nitro-phenol;6-FLUORO-2-NITROPHENOL;2-FLUORO-6-NITROPHENOL;2-NITRO-6-FLUORO PHENOL;fluoro-2 nitro-6 phenol;Phenol,2-fluoro-6-nitro-;Fluoro-6-nitrophenol, 2-;2-Fluoro-6-nitrophenol98%;2-Fluoro-6-nitrophenol>
- CBNumber:
- CB7371453
- Molecular Formula:
- C6H4FNO3
- Molecular Weight:
- 157.1
- MDL Number:
- MFCD00042446
- MOL File:
- 1526-17-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 92-94°C |
|---|---|
| Boiling point | 201.5±20.0 °C(Predicted) |
| Density | 1.511±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 5.67±0.24(Predicted) |
| color | Light yellow to Yellow to Orange |
| BRN | 1870307 |
| InChI | InChI=1S/C6H4FNO3/c7-4-2-1-3-5(6(4)9)8(10)11/h1-3,9H |
| InChIKey | HIGRXCJEFUYRNW-UHFFFAOYSA-N |
| SMILES | C1(O)=C([N+]([O-])=O)C=CC=C1F |
| CAS DataBase Reference | 1526-17-6(CAS DataBase Reference) |
| EPA Substance Registry System | 2-Fluoro-6-nitrophenol (1526-17-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H301-H335 | |||||||||
| Precautionary statements | P261-P280a-P301+P310a-P305+P351+P338-P405-P501a-P264-P270-P280-P301+P312+P330-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P501 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26-36/37/39-36/37 | |||||||||
| RIDADR | 2811 | |||||||||
| HazardClass | IRRITANT | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29089990 | |||||||||
| NFPA 704 |
|
2-Fluoro-6-nitrophenol price More Price(56)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | F0623 | 2-Fluoro-6-nitrophenol >98.0%(GC) | 1526-17-6 | 1g | $26 | 2026-04-30 | Buy |
| TCI Chemical | F0623 | 2-Fluoro-6-nitrophenol >98.0%(GC) | 1526-17-6 | 5g | $76 | 2026-04-30 | Buy |
| Apolloscientific | PC3970 | 2-Fluoro-6-nitrophenol 98% | 1526-17-6 | 25g | $36 | 2026-06-04 | Buy |
| Activate Scientific | AS33408 | 6-Fluoro-2-nitrophenol 98% | 1526-17-6 | 5g | $27 | 2026-06-04 | Buy |
| Activate Scientific | AS33408 | 6-Fluoro-2-nitrophenol 98% | 1526-17-6 | 25g | $75 | 2026-06-04 | Buy |
2-Fluoro-6-nitrophenol Chemical Properties, Uses, Production
Uses
2-Fluoro-6-nitrophenol has antifungal- and high plant-growth-regulating activity.
Synthesis
367-12-4
7440-44-0
1526-17-6
403-19-0
A. Synthesis of 2-fluoro-4-nitrophenol To a stirred dichloromethane solution of 2-fluorophenol (32.3 g, 0.288 mol) was slowly added 90% nitric acid (1 g, 0.31 mol HNO3) in an ice-salt bath cooled to -10°C. The addition process was controlled to be completed in 1 hour. During the reaction, the temperature was maintained at about -5 °C. After the addition was completed, stirring was continued at 0°C for 1 hour. At the end of the reaction, the precipitate was collected by filtration and washed several times with cold dichloromethane. Analysis by GC and thin layer chromatography (silica gel, 7:3 hexane-acetone) showed that the product was mainly a single compound and that the by-products produced in the reaction were of low polarity and volatility. The solid was dissolved in ether, washed with water, dried (MgSO4) and the solvent evaporated. The resulting solid was recrystallized with methylcyclohexane to give 13 g of a pale yellow solid with a melting point of 119°-121°C. NMR (CDCl3) analysis confirmed the product as 2-fluoro-4-nitrophenol. The dichloromethane mother liquor was treated, washed with water, dried (MgSO4) and the solvent evaporated. The solid obtained was ground with boiling hexane (3 x 150 ml) to effectively remove the least polar and highly volatile reaction by-products. The hexane solution was treated with activated charcoal, filtered and concentrated to about 300 ml and cooled to give 13.5 g (30% yield) of the by-product 2-fluoro-6-nitrophenol as a yellow solid with a melting point of 70°-86 °C.
References
[1] Patent: US4750931, 1988, A
[2] Patent: EP142328, 1991, B1
2-Fluoro-6-nitrophenol Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Liuyang huarui material technology co., ltd. | 13467605171 | 2580432242@qq.com | China | 184 | 58 |
| Shanghai Prescrina Pharmaceutical Technology Co., LTD | 18367323072 | 2125193158@qq.com | China | 362 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
View Latest Price from 2-Fluoro-6-nitrophenol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 2-Fluoro-6-nitrophenol
1526-17-6
|
$8.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2022-02-25 | 2-Fluoro-6-nitrophenol
1526-17-6
|
$10.00 | 1KG | 99% | 10Tons | Hebei Senko Biotechnology Co., Ltd. | |
 |
2020-01-09 | 2-Fluoro-6-nitrophenol
1526-17-6
|
$1.00 | 1KG | 95-99% | 1ton | Career Henan Chemical Co |
-
- 2-Fluoro-6-nitrophenol
1526-17-6
- $8.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 2-Fluoro-6-nitrophenol
1526-17-6
- $10.00
- 99%
- Hebei Senko Biotechnology Co., Ltd.
-
- 2-Fluoro-6-nitrophenol
1526-17-6
- $1.00
- 95-99%
- Career Henan Chemical Co
