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2-Fluorophenol

CAS No.
367-12-4
Chemical Name:
2-Fluorophenol
Synonyms
1-Bromo-3-fluorobezene;O-FLUOROPHENOL;uorophenoL;2-Florophenol;2-Flurophenol;2-fluoro-pheno;2-FLUOROPHENOL;o-fluoro-pheno;2-Fluorophenole;2-Fluorophenol f
CBNumber:
CB0495831
Molecular Formula:
C6H5FO
Molecular Weight:
112.1
MDL Number:
MFCD00002155
MOL File:
367-12-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-10 10:27:02
Product description Number Pack Size Price
2-Fluorophenol 98% F12804 10g $50.4
2-Fluorophenol >98.0%(GC) F0150 25g $18
2-Fluorophenol >98.0%(GC) F0150 250g $101
o-Fluorophenol, min. 98% 09-4070 10g $48
o-Fluorophenol, min. 98% 09-4070 50g $192
More product size

2-Fluorophenol Properties

Melting point 16.1 °C (lit.)
Boiling point 171-172 °C/741 mmHg (lit.)
Density 1.256 g/mL at 25 °C (lit.)
refractive index n20/D 1.511(lit.)
Flash point 116 °F
storage temp. Inert atmosphere,Room Temperature
solubility 37.7g/l
pka 8.73(at 25℃)
form Liquid
color Clear colorless to light yellow-brownish
Specific Gravity 1.256
Water Solubility 80.72g/L(25 ºC)
BRN 1905112
Henry's Law Constant 3.1×100 mol/(m3Pa) at 25℃, Abraham et al. (1994)
Stability Stable. Flammable. Incompatible with strong oxidizing agents.
InChI 1S/C6H5FO/c7-5-3-1-2-4-6(5)8/h1-4,8H
InChIKey HFHFGHLXUCOHLN-UHFFFAOYSA-N
SMILES Oc1ccccc1F
CAS DataBase Reference 367-12-4(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII I9OW1NLY9R
NIST Chemistry Reference Phenol, 2-fluoro-(367-12-4)
EPA Substance Registry System o-Fluorophenol (367-12-4)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Warning
Hazard statements  H226-H315-H319
Precautionary statements  P210-P233-P240-P241-P303+P361+P353-P305+P351+P338
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xn,F,C,Xi,T
Risk Statements  20/21/22-36/37/38-10-63-43-23/24/25-45-40
Safety Statements  28-36/37-36/37/39-26-16-24/25-23-53-36
RIDADR  UN 1993 3/PG 3
WGK Germany  3
RTECS  SL4530000
Hazard Note  Flammable/Corrosive
TSCA  TSCA listed
HazardClass  3
PackingGroup  III
HS Code  29081000
Storage Class 3 - Flammable liquids
Hazard Classifications Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Aquatic Chronic 3
Eye Irrit. 2
Flam. Liq. 3
Skin Irrit. 2
Limited Quantities 5.0 L (1.3 gallons) (liquid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
2
2 0

2-Fluorophenol price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich F12804 2-Fluorophenol 98% 367-12-4 10g $50.4 2026-03-19 Buy
TCI Chemical F0150 2-Fluorophenol >98.0%(GC) 367-12-4 25g $18 2026-03-19 Buy
TCI Chemical F0150 2-Fluorophenol >98.0%(GC) 367-12-4 250g $101 2026-03-19 Buy
Strem Chemicals 09-4070 o-Fluorophenol, min. 98% 367-12-4 10g $48 2024-03-01 Buy
Strem Chemicals 09-4070 o-Fluorophenol, min. 98% 367-12-4 50g $192 2024-03-01 Buy
Product number Packaging Price Buy
F12804 10g $50.4 Buy
F0150 25g $18 Buy
F0150 250g $101 Buy
09-4070 10g $48 Buy
09-4070 50g $192 Buy

2-Fluorophenol Chemical Properties,Uses,Production

Chemical Properties

Clear colourless to yellow liquid

Uses

2-Fluorophenol is a competitive inhibitor in the oxidation of 3,4-dihydroxyphenylalanine (L-DOPA), a catecholamine precursor that is used as a therapeutic agent for patients with ParkinsonтАЩs disease. 2-Fluorophenol is also used as a sole carbon energy source for bacteria.

Synthesis Reference(s)

Tetrahedron, 52, p. 23, 1996 DOI: 10.1016/0040-4020(95)00867-8
Journal of the American Chemical Society, 103, p. 1964, 1981 DOI: 10.1021/ja00398a015

General Description

Liquid or crystalline solid melting at 14-16°C. Corrosive. Density 1.246 g / cm3.

Air & Water Reactions

Highly flammable.

Reactivity Profile

2-Fluorophenol reacts as a weak organic acid. May be incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction with bases. Such heating may initiate polymerization of the organic compound. Sulfonated very readily (for example, by concentrated sulfuric acid at room temperature). The reactions generate heat. Nitrated very rapidly, even by dilute nitric acid.

Health Hazard

ACUTE/CHRONIC HAZARDS: Toxic and irritant.

Purification Methods

Pass o-fluorophenol at least twice through a gas chromatographic column for small quantities; otherwise fractionally distil it under reduced pressure. [Beilstein 6 I 97, 6 IV 770.]

Global( 498)Suppliers
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View Lastest Price from 2-Fluorophenol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Fluorophenol pictures 2026-04-29 2-Fluorophenol
367-12-4
US $0.00 / KG 25KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
2-Fluorophenol pictures 2026-03-20 2-Fluorophenol
367-12-4
US $10.00 / KG 100KG 99% 100 mt Hebei Chuanghai Biotechnology Co., Ltd
2-Fluorophenol pictures 2026-01-04 2-Fluorophenol
367-12-4
US $0.00-0.00 / kg 0.1kg 99.0%min 2000kg Hangzhou ICH Biofarm Co., Ltd
  • 2-Fluorophenol pictures
  • 2-Fluorophenol
    367-12-4
  • US $0.00 / KG
  • 98%min
  • WUHAN FORTUNA CHEMICAL CO., LTD
  • 2-Fluorophenol pictures
  • 2-Fluorophenol
    367-12-4
  • US $10.00 / KG
  • 99%
  • Hebei Chuanghai Biotechnology Co., Ltd
  • 2-Fluorophenol pictures
  • 2-Fluorophenol
    367-12-4
  • US $0.00-0.00 / kg
  • 99.0%min
  • Hangzhou ICH Biofarm Co., Ltd
2-Florophenol 2-FLUOROHYDROXYBENZENE 2-FLUOROPHENOL 1-Fluoro-2-hydroxybenzene 2-fluoro-pheno 2-Hydroxyfluorobenzene 2-Fluorophenol, 97+% Adjacent fluorine phenol O-FLUOROPHENOL 2-Hydroxy Phenyl Fluoride uorophenoL o-fluoro-pheno Phenol, o-fluoro- Fluorophenolmincolorlessliq 1-Bromo-3-fluorobezene o-Fluorophenol,min.98% Phenol, 2-fluoro- 2-Fluorophenol99% 2-Fluorophenol (95-98%) 2-Flurophenol 2-Fluorophenol f o-Fluorophenol 2-Fluorophenol 2-FLUOROPHENOL, 1000MG, NEAT 2-FLUOROPHENOL 98% (GC) 2-Fluorophenol,98% o-Fluorophenol, min. 98% 2-Fluorophenol 1g [367-12-4] 2-Fluorophenol solution 2-Fluorophenole 2-Fluorophenol @2.0 mg/mL in MeOH 2-Fluorophenol> 2-FluorophenolSolution,100mg/L,10ml 2-FluorophenolSolution,7,500mg/L,1ml 2-Fluorophenol@0.2 mg/mL in CH2Cl2 2-Fluorophenol (95-98%) @0.1 mg/mL in Acetone 2-Fluorophenol @2.0 mg/mL in CH2Cl2 2-Fluorophenol ISO 9001:2015 REACH 2-Fluorophenol pure, 98% Phloroglucinol Impurity 226 2-Fluorophenol in isooctane CA13797000 2-Fluorophenol 2-Fluorophenol in Methanol 2-Fluorophenol 1000 μg/mL in Methanol 367-12-4 367-41-5 1852-11-3 369-12-4 FA - FL Phenols Oxygen Compounds Organic Building Blocks Building Blocks Analytical Standards Analytical Chromatography Product Catalog Alphabetic ALCOHOL alcohol| alkyl Fluorine Organic Fluorinated Building Blocks