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2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane

2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane Structure
2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane structure
CAS No.
83558-87-6
Chemical Name:
2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane
Synonyms
6FAP;AHHFP;BIS-AP-AF;4,4'-(Perfluoropropane-2,2-diyl)bis(2-aminophenol);BAFA;BAPAF;2,2-Bis(3-aMino-4-hydroxylphenyl)hexafluoropropane(6FAP);1,1-Bis(3-aMino-4-hydroxyphenyl)-2,2,2-trifluoro-1-(trifluoroMethyl)ethane;Bis-AP-AF2;Bis-AP-AF/6FAP
CBNumber:
CB7397729
Molecular Formula:
C15H12F6N2O2
Molecular Weight:
366.26
MDL Number:
MFCD00039147
MOL File:
83558-87-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:56:19
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2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane Properties

Melting point 245-248 °C (lit.)
Boiling point 411.3±45.0 °C(Predicted)
Density 1.545±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 9.07±0.10(Predicted)
color White to Off-White
InChI InChI=1S/C15H12F6N2O2/c16-14(17,18)13(15(19,20)21,7-1-3-11(24)9(22)5-7)8-2-4-12(25)10(23)6-8/h1-6,24-25H,22-23H2
InChIKey MSTZGVRUOMBULC-UHFFFAOYSA-N
SMILES C(C1=CC=C(O)C(N)=C1)(C1=CC=C(O)C(N)=C1)(C(F)(F)F)C(F)(F)F
CAS DataBase Reference 83558-87-6(CAS DataBase Reference)
EPA Substance Registry System Phenol, 4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]bis[2-amino- (83558-87-6)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
Hazard Note  Irritant
TSCA  TSCA listed
HS Code  29222990
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
0
2 0

2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane price More Price(67)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 541710 2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane 97% 83558-87-6 5g $92.9 2026-04-30 Buy
TCI Chemical B1415 2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane >98.0%(T) 83558-87-6 5g $86 2026-04-30 Buy
TCI Chemical B1415 2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane >98.0%(T) 83558-87-6 25g $257 2026-04-30 Buy
Usbiological 264309 2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane Asreported 83558-87-6 10g $368 2026-06-03 Buy
Usbiological 264309 2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane Asreported 83558-87-6 25g $511 2026-06-03 Buy
Product number Packaging Price Buy
541710 5g $92.9 Buy
B1415 5g $86 Buy
B1415 25g $257 Buy
264309 10g $368 Buy
264309 25g $511 Buy

2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane Chemical Properties, Uses, Production

Description

2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane (6FAP,83558-87-6) is white crystal. Its boiling point and density are expected to be 411.3±45.0 °C and 1.545±0.06 g/cm3, respectively. It is slightly soluble in DMSO and methanol.The product is non-toxic and can be stored at room temperature away from light and air.

Synthesis

30 g two (3-nitro-4-hydroxyphenyl) hexafluoropropanes are dropped into the 1000 mL autoclave, add 300 g DMF and 1.5 g palladium/carbon (the mass fraction of palladium in the palladium/carbon is 5%), press hydrogen to 1MPa, open stirring and be warmed up to 70 ℃, stop reaction after two (3-nitro-4-hydroxyphenyl) hexafluoropropane content＜0.1%, target product two (3-amino-4-hydroxyphenyl) hexafluoropropane Fluoropropane gas phase content is 98%, and the system is black, and the temperature of the still is lowered to room temperature, filtered, and the filtrate is de-dried under reduced pressure at 70-80°C to obtain bis(3-amino-4-hydroxyphenyl) hexafluoropropane crude product , the crude product is recrystallized, the recrystallization solvent is water and DMF, and the mass ratio of bis(3-amino-4-hydroxyphenyl)hexafluoropropane, water and DMF is 1:4:2.
First, the bis(3-nitro-4-hydroxyphenyl) hexafluoropropane crude product is mixed with the recrystallization solvent to increase the still temperature to 60 °C and stir, and then the still temperature is reduced to 10-20 °C for crystallization, filtered, After drying, 25.4 g of pure bis(3-nitro-4-hydroxyphenyl)hexafluoropropane was obtained. The yield of bis(3-amino-4-hydroxyphenyl)hexafluoropropane was 98.3% and the purity was 99.6%. 1H-NMR (400MHz, D6-DMSO) δ (ppm): 4.64 (s, 4H), 6.42 (d, 2H), 7.57 (s, 2H), 6.65 (d, 2H), 9.36 (s, 2H). 19F-NMR (400MHz, D6-DMSO) δ (ppm): -62.78. [1].2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane

Physical properties

White powder

Uses

2,2-bis(3-amino-4-hydroxyphenyl)hexafluoropropane（BisAPAF） is a polyimide monomer.It is mairly used in the aynthesis of the heat resisting polymers,especially in the manufacture of specialty polymeoric electronic material-fluorinated polyimides.

Application

2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane (Bis-AP-AF/6FAP) consists of two aminophenols bridged with a hexafluoropropane. The reaction of Bis-AP-AF and BTDA can be used to synthesise polyimide (PI) films. The tensile strength, tensile modulus and elongation at break of the PI films were significantly improved by 60Co irradiation with an optimum irradiation dose of 50 kGy. The maximum increments in tensile strength, tensile modulus and elongation at break of the irradiated PI films were 37.8%, 45.0% and 95.2%, respectively. The high proton conductivity and good chemical and thermal stability of these fluorinated films make them most suitable for use in fuel cell systems. In addition, Bis-AP-AF can be used to synthesise polybenzoxazole (TR-PBO) membranes for use as semiconductor fabrication materials.

General Description

2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane, also referred to as 4,4′-(1,1,1,3,3,3-hexafluoro-2,2-propanediyl)bis(2-aminophenol), is an aromatic diamine.

2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane synthesis

73340-33-7
83558-87-6
Synthesis of 2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane from Phenol, 4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]bis[2-nitro-

2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane Preparation Products And Raw materials

Raw materials

Phenol, 4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]bis[2-nitro-

Preparation Products

2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane Suppliers

Global Suppliers ( 431)
Supplier Tel Email Country ProdList Advantage
CHINATECH(TIANJIN) CHEMICAL CO.,LTD. 18222205756 sales6@chinatechem.com China 100 58
Hubei Xinkang Pharmaceutical Chemical Co., Ltd 027-027-59308705 18871579363 1248680011@qq.com China 9279 58
LinkChem Technology Co., Ltd. 58950110 13124863828 sales@linkchem.cn China 2993 58
Shangfluoro 021-65170832 15601903708 qinba_2@163.com China 318 58
Heynova (Shanghai) New Material Technology CO., Ltd 17821102608 zoe@heynovachem.com China 211 58
Ningbo Agracechem Technology Co., Ltd. 0574-87621641 13989375151 tianze@agracechem.com China 36 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Changzhou Sunlight Pharmaceutical Co., Ltd 519-83131668 15995063688 info@sunlightchem.com China 100 69
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
future industrial shanghai co., ltd 400-0066400 13621662912 sales@jonln.com China 1989 65
Supplier Advantage
CHINATECH(TIANJIN) CHEMICAL CO.,LTD. 58
Hubei Xinkang Pharmaceutical Chemical Co., Ltd 58
LinkChem Technology Co., Ltd. 58
Shangfluoro 58
Heynova (Shanghai) New Material Technology CO., Ltd 58
Ningbo Agracechem Technology Co., Ltd. 58
J & K SCIENTIFIC LTD. 76
Changzhou Sunlight Pharmaceutical Co., Ltd 69
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
future industrial shanghai co., ltd 65

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Related Questions

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Q:What is 2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane?Zora - Oct 13,2025
A:2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane is an important compound used as a raw material for functional polymers such as polyimide, polyamide, and polybenzoxazole.A method for producing 2,2-bis(3-amino-4-hydroxyphenyl)-1,1,1,3,3,3-hexafluoropropane which comprises reducing 2,2-bis(3-nitro-4-hydroxyphenyl)-1,1,1,3,3,3-hexafluoropropane with hydrazines in the presence of a platinum and/or palladium catalyst.

View Latest Price from 2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane pictures 2026-09-18 2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane
83558-87-6
 $24.00-151.00 25g 0.98 100kg Shanghai UCHEM Inc.
2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane pictures 2026-09-18 2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane
83558-87-6
 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane pictures 2026-09-07 2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane
83558-87-6
 1kg 99.9%min 20tons HANGZHOU HAILAN CHEMICAL CO.,LTD.

2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane Spectrum

2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane(83558-87-6)MS2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane(83558-87-6)1HNMR2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane(83558-87-6)13CNMR2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane(83558-87-6)IR12,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane(83558-87-6)IR2

83558-87-6 (2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane) Related Search:

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1,1-Bis(3-aMino-4-hydroxyphenyl)-2,2,2-trifluoro-1-(trifluoroMethyl)ethane 2,2-Bis(3-aMino-4-hydroxylphenyl)hexafluoropropane(6FAP) 2-aMino-4-[2-(3-aMino-4-hydroxyphenyl)-1,1,1,3,3,3-hexafluoropropan-2-yl]phenol 2,2-Bis(3-amino-4-hydroxyphenyl)hexafluopropane 2,2-Bis(3-amino-4-hydroxyphenyl)-hexafluoropropane(Bis-AP-AF/6FAP) 4,4'-(HEXAFLUOROISOPROPYLIDENE)BIS(2-AMINOPHENOL) 2,2-BIS(3-AMINO-4-HYDROXYPHENYL)HEXAFLUOROPROPANE 2,2'-DIAMINO-4,4'-(PERFLUOROPROPANE-2,2-DIYL)DIPHENOL 2,2-BIS(3-AMINO-4-HYDROXYPHENYL)HEXAFLUO 2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane,6-FAP 2,2-Bis(3-amino-4-hydroxyphenyl)-1,1,1,3,3,3-hexafluoropropane 4,4'-(1,1,1,3,3,3-Hexafluoropropane-2,2-diyl)bis(2-aminophenol) 4,4'-[Bis(trifluoromethyl)methylene]bis(2-aminophenol) Phenol, 4,4'-(2,2,2-trifluoro-1-(trifluoromethyl)ethylidene)bis(2-amino- 2,2-bis(3-amino-4-hy 2,2-bis(3-amino-4-hydroxyphenyl) -hexafluoropropane (Bis-AP-AF) 2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane 99% 2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane99% 2,2-Bis(3-amino-4-hydroxyphenyl)- BAPAF 2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane > BAFA 2-Amino-4-[1-(3-amino-4-hydroxy-phenyl)-2,2,2-trifluoro-1-(trifluoromethyl)ethyl]phenol 2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane USP/EP/BP 2-aMino-4-[2-(3-aMino-4-hydroxyphenyl)-1,1,1,3,3,3- Bis-AP-AF2 Bis-AP-AF/6FAP O-aminobisphenol AF 2,2-Bis(3-amino-4-hydroxyphenyI)hexafluoropropane (6FAP) 4,4'-(Perfluoropropane-2,2-diyl)bis(2-aminophenol) 6FAP AHHFP BIS-AP-AF 2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane?-3 83558-87-6 F3C2CC6H3NH2OH2 C15H12F6N2O2 Organic Building Blocks Oxygen Compounds Bisphenol AF type Compounds (for High-Performance Polymer Research) Reagent for High-Performance Polymer Research Building Blocks Amino Alcohols fine chemicals, specialty chemicals, intermediates, electronic chemical, organic synthesis, Organic Building Blocks Bisphenol AF type Compounds (for High-Performance Polymer Research) Functional Materials Reagent for High-Performance Polymer Research Amino Alcohols Organic Building Blocks Oxygen Compounds fine chemicals, specialty chemicals, intermediates, electronic chemical, organic synthesis, functional materials 83558-87-6 PI