3-Amino-6-morpholinopyridine
- CAS No.
- 52023-68-4
- Chemical Name:
- 3-Amino-6-morpholinopyridine
- Synonyms
- AKOS B034244;BUTTPARK 99\12-14;OTAVA-BB BB7018930038;6-MORPHOLINOPYRIDIN-3-AMINE;6-MORPHOLINO-3-PYRIDINAMINE;3-AMINO-6-MORPHOLINOPYRIDINE;6-Morpholinopyridine-3-amine;6-Morpholinopyridine-3-Amino;5-Amino-2-morpholinopyridine;6-MORPHOLIN-4-YLPYRIDIN-3-AMINE
- CBNumber:
- CB5320215
- Molecular Formula:
- C9H13N3O
- Molecular Weight:
- 179.22
- MDL Number:
- MFCD00119562
- MOL File:
- 52023-68-4.mol
- MSDS File:
- SDS
| Melting point | 126-128°C |
|---|---|
| Boiling point | 414.4±45.0 °C(Predicted) |
| Density | 1.208±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | 6.48±0.10(Predicted) |
| Appearance | Brown to black Solid |
| CAS DataBase Reference | 52023-68-4(CAS DataBase Reference) |
| FDA UNII | KB19HWM93G |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22-22 | |||||||||
| Safety Statements | 22-36/37/39-36/37 | |||||||||
| RIDADR | 2811 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2934999090 | |||||||||
| NFPA 704 |
|
3-Amino-6-morpholinopyridine price More Price(49)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR23613 | 6-(Morpholin-4-yl)pyridin-3-amine 97% | 52023-68-4 | 100mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR23613 | 6-(Morpholin-4-yl)pyridin-3-amine 97% | 52023-68-4 | 250mg | $24 | 2026-06-04 | Buy |
| Apolloscientific | OR23613 | 6-(Morpholin-4-yl)pyridin-3-amine 97% | 52023-68-4 | 1g | $60 | 2026-06-04 | Buy |
| Apolloscientific | OR23613 | 6-(Morpholin-4-yl)pyridin-3-amine 97% | 52023-68-4 | 5g | $228 | 2026-06-04 | Buy |
| Apolloscientific | OR23613 | 6-(Morpholin-4-yl)pyridin-3-amine 97% | 52023-68-4 | 25g | $1090 | 2026-06-04 | Buy |
3-Amino-6-morpholinopyridine Chemical Properties, Uses, Production
Uses
5-Amino-2-(4-morpholinyl)pyridine is used as pharmaceutical intermediate.
Synthesis
26820-62-2
52023-68-4
General procedure for the synthesis of 3-amino-6-morpholinopyridine from 4-(5-nitropyridin-2-yl)morpholine: a mixture of 1.65 g (7.8 mmol) of 4-(5-nitro-2-pyridinyl)morpholine, 160 mg of 5% Pt/C catalyst, and 20 mL of ethanol was placed in a reactor. The reaction was carried out under 50 psi hydrogen atmosphere for 5 hours. Upon completion of the reaction, the mixture was filtered through a pad of diatomaceous earth to remove the catalyst, followed by evaporation of the solvent under reduced pressure to afford 1.4 g (100% yield) of 6-(4-morpholino)-3-pyridinamine, the product being a purple solid. Its 1H NMR (400 MHz, DMSO-d6) data were as follows: δ 7.60 (d, J=2.9 Hz, 1H), 6.92 (dd, J=8.8 and 2.9 Hz, 1H), 6.62 (d, J=8.8 Hz, 1H), 4.59 (brs, 2H), 3.65-3.72 (m, 4H), 3.17 (dt, J= 4.9 and 2.4 Hz, 4H).
References
[1] Patent: WO2009/32667, 2009, A1. Location in patent: Page/Page column 148
[2] Patent: WO2009/76140, 2009, A1. Location in patent: Page/Page column 237
[3] Patent: WO2010/104899, 2010, A1. Location in patent: Page/Page column 106
[4] Patent: WO2009/154769, 2009, A1. Location in patent: Page/Page column 35
[5] Patent: WO2014/12360, 2014, A1. Location in patent: Paragraph 00355
3-Amino-6-morpholinopyridine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7881 | 64 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shanghai Ennopharm Co., Ltd. | +86 (21) 6435-5022 | China | 4263 | 65 | |
| Shanghai yirong biology science and technology co., ltd | 18049974220 | 3060526242@qq.com | China | 999 | 60 |
View Latest Price from 3-Amino-6-morpholinopyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | 6-Morpholinopyridin-3-amine
52023-68-4
|
$3.00-9.00 | 99% | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |||
 |
2019-07-06 | 3-Amino-6-morpholinopyridine
52023-68-4
|
$1.00 | 1KG | 99% | Career Henan Chemical Co |
-
- 6-Morpholinopyridin-3-amine
52023-68-4
- $3.00-9.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 3-Amino-6-morpholinopyridine
52023-68-4
- $1.00
- 99%
- Career Henan Chemical Co
