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ChemicalBook >> CAS DataBase List >>3,9,10-trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2-ol chloride

3,9,10-trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2-ol chloride

3,9,10-trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2-ol chloride Structure
3,9,10-trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2-ol chloride structure
CAS No.
1916-10-5
Chemical Name:
3,9,10-trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2-ol chloride
Synonyms
Columbamine chloride;3,9,10-trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2-ol chloride
CBNumber:
CB74298974
Molecular Formula:
C20H20ClNO4
Molecular Weight:
373.83
MDL Number:
MOL File:
1916-10-5.mol
MSDS File:
SDS
Last updated:2026-05-28 03:29:01
Request For Quotation

3,9,10-trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2-ol chloride Properties

Melting point 239.5-240.5 °C
form Solid
color Light yellow to yellow
Major Application food and beverages
pharmaceutical
UNSPSC Code 12352200
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
WGK Germany  WGK 3
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral

3,9,10-trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2-ol chloride price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0898361 Columbamine (chloride) 99.62% 1916-10-5 5mg $152 2026-06-04 Buy
ChemScene CS-0898361 Columbamine (chloride) 99.62% 1916-10-5 10mg $238 2026-06-04 Buy
aablocks AA023SRL Columbamine chloride >98% 1916-10-5 5mg $191 2026-06-01 Buy
aablocks AA023SRL Columbamine chloride >98% 1916-10-5 10mg $280 2026-06-01 Buy
Product number Packaging Price Buy
CS-0898361 5mg $152 Buy
CS-0898361 10mg $238 Buy
AA023SRL 5mg $191 Buy
AA023SRL 10mg $280 Buy

3,9,10-trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2-ol chloride Chemical Properties, Uses, Production

Uses

food and beverages
pharmaceutical

in vivo

Columbamine (5-20 mg/kg; 23 days) significantly decreases the tumor volumes in a dose-dependent manner in HCT116 xenograft mice model[4].

Animal Model:Six-weeks-old male BALB/c nude mice (subcutaneously injected with HCT116 and control cells on the opposite flanks of the same mouse)[4]
Dosage:5, 10, 20 mg/kg
Administration:Administered to experimental mice for 23 days
Result:Decreased the tumor volumes in a dose-dependent manner.

IC 50

CYP3A4: 30.6 μM (IC50)

3,9,10-trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2-ol chloride Preparation Products And Raw materials

Raw materials

Preparation Products

3,9,10-trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2-ol chloride Suppliers

Global Suppliers ( 17)
Supplier Tel Email Country ProdList Advantage
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai Standard Technology Co.,Ltd. 021-021-57127007-6622-6622 17621252073 luzh@nature-standard.com China 3021 58
Guangzhou Younan Technology Co., Ltd 020-82000279 18988941452 YN_research@163.com China 2984 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
Shanghai Taopu Industrial Co., LTD 15900573766 18018507602 3165608826@qq.com China 4403 58
Wuhan Huangzhen Biochemical Co., Ltd 13795480948 3450865996@qq.com China 4956 58
Hubei CuiRan Biotechnology Co., Ltd. 18162795156 18162795156 3391961471@qq.com China 4967 58
TLC Pharmaceutical Standards Ltd. 18012923235 18012923235 chinasales04@tlcstandards.com.cn China 7839 58
Chengdu Biopurify Ltd. 82633860 18982077548 cwb1@biopurify.cn China 4630 58
TLC Pharmaceutical Standards Ltd. 18012923235 chinasales04@tlcstandards.com.cn China 8301 58
Supplier Advantage
Shanghai YuanYe Biotechnology Co., Ltd. 60
Shanghai Standard Technology Co.,Ltd. 58
Guangzhou Younan Technology Co., Ltd 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
Shanghai Taopu Industrial Co., LTD 58
Wuhan Huangzhen Biochemical Co., Ltd 58
Hubei CuiRan Biotechnology Co., Ltd. 58
TLC Pharmaceutical Standards Ltd. 58
Chengdu Biopurify Ltd. 58
TLC Pharmaceutical Standards Ltd. 58

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3,9,10-trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2-ol chloride Columbamine chloride 1916-10-5