2-Methyl-[1,2,6]thiadiazinane 1,1-dioxide
- CAS No.
- 137830-77-4
- Chemical Name:
- 2-Methyl-[1,2,6]thiadiazinane 1,1-dioxide
- Synonyms
- 2-Methyl-[1,2,6]thiadiazinane 1,1-dioxide;2H-1,2,6-Thiadiazine, tetrahydro-2-methyl-, 1,1-dioxide;2-methyl-3,4,5,6-tetrahydro-1,2,6-thiadiazine-1,1-dioxide
- CBNumber:
- CB7438833
- Molecular Formula:
- C4H10N2O2S
- Molecular Weight:
- 150.2
- MDL Number:
- MFCD06657763
- MOL File:
- 137830-77-4.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
2-Methyl-[1,2,6]thiadiazinane 1,1-dioxide price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | MFA83077 | 2-Methyl-1,2,6-thiadiazinane 1,1-dioxide | 137830-77-4 | 1g | $342.2 | 2026-06-04 | Buy |
| Biosynth | MFA83077 | 2-Methyl-1,2,6-thiadiazinane 1,1-dioxide | 137830-77-4 | 10g | $2596 | 2026-06-04 | Buy |
| Matrix Scientific | 303440 | 2-Methyl-1,2,6-thiadiazinane 1,1-dioxide | 137830-77-4 | 250.00mg | $71 | 2026-05-19 | Buy |
| Matrix Scientific | 303440 | 2-Methyl-1,2,6-thiadiazinane 1,1-dioxide | 137830-77-4 | 1.00g | $143 | 2026-05-19 | Buy |
| Matrix Scientific | 303440 | 2-Methyl-1,2,6-thiadiazinane 1,1-dioxide | 137830-77-4 | 5.00g | $611 | 2026-05-19 | Buy |
2-Methyl-[1,2,6]thiadiazinane 1,1-dioxide Chemical Properties, Uses, Production
Synthesis
6291-84-5
137830-77-4
The general procedure for the synthesis of 2-methyl-[1,2,6]thiadiazine 1,1-dioxide from 3-methylaminopropylamine was as follows: a mixture of N-methyl-1,3-propanediamine (2.06 g, 23.4 mmol) and sulfonamide (0.748 g, 7.78 mmol) was placed in a microwaveable reaction flask, sealed, and then filled with argon gas for protection. The reaction flask was stirred overnight at 50°C, and then warmed to 160°C to continue the reaction with stirring for 20 minutes. Upon completion of the reaction, the reaction mixture was concentrated and the residue was purified by column chromatography to afford 2-methyl-1,2,6-thiadiazine 1,1-dioxide (0.82 g, 70% yield).
References
[1] Journal of Medicinal Chemistry, 1994, vol. 37, # 19, p. 3023 - 3032
[2] European Journal of Medicinal Chemistry, 2007, vol. 42, # 9, p. 1176 - 1183
[3] Patent: WO2015/108861, 2015, A1. Location in patent: Paragraph 00401
[4] Patent: US2015/225422, 2015, A1. Location in patent: Paragraph 0555-0556
[5] Patent: US2013/303524, 2013, A1. Location in patent: Paragraph 0405-0406
2-Methyl-[1,2,6]thiadiazinane 1,1-dioxide Preparation Products And Raw materials
2-Methyl-[1,2,6]thiadiazinane 1,1-dioxide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
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| CR Corporation Limited | fred.wen@crcorporation.cn | China | 8642 | 58 | |
| Shanghai Pleikon Chemical Technology Co., Ltd | 021-54321516 17717324060 | 2719672468@qq.com | China | 2227 | 58 |





