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4-Methoxy-3-buten-2-one

CAS No.
51731-17-0
Chemical Name:
4-Methoxy-3-buten-2-one
Synonyms
4-methoxy-3-butene-2-one;TRANS-4-METHOXY-3-BUTEN-2-ONE;Einecs 257-364-0;4-Methoxy-3-buten-2-one;Trans 4-Methoxy Butenone;(E)-4-methoxy-3-buten-2-one;(3E)-4-Methoxy-3-buten-2-one;(3E)-4-Methoxybut-3-en-2-one;TRANS-1-METHOXY-1-BUTEN-3-ONE;3-Buten-2-one,4-methoxy-, (3E)-
CBNumber:
CB7449808
Molecular Formula:
C5H8O2
Molecular Weight:
100.12
MDL Number:
MFCD00008778
MOL File:
51731-17-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:54:57

4-Methoxy-3-buten-2-one Properties

Melting point 0℃
Boiling point 200 °C (lit.)
Density 0.982 g/mL at 25 °C (lit.)
refractive index n20/D 1.468(lit.)
Flash point 146 °F
storage temp. 2-8°C
solubility sol THF, ether, acetonitrile, benzene.
form liquid
Appearance Colorless to light yellow Liquid
BRN 2070991
InChI InChI=1S/C5H8O2/c1-5(6)3-4-7-2/h3-4H,1-2H3/b4-3+
InChIKey VLLHEPHWWIDUSS-ONEGZZNKSA-N
SMILES CC(=O)/C=C/OC
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H227-H302-H315-H319-H335
Precautionary statements  P210-P235-P261-P280-P302+P352-P304+P340-P305+P351+P338-P370+P378-P403+P235
PPE Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Risk Statements  10
Safety Statements  23-24/25
RIDADR  1224
WGK Germany  3
10-21
Storage Class 10 - Combustible liquids

4-Methoxy-3-buten-2-one price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 122068 trans-4-Methoxy-3-buten-2-one technical grade, 90% 51731-17-0 10g $108 2026-04-30 Buy
Sigma-Aldrich 122068 trans-4-Methoxy-3-buten-2-one technical grade, 90% 51731-17-0 50g $328 2026-04-30 Buy
aablocks AA0035N6 trans-4-Methoxy-3-buten-2-one 90%GC 51731-17-0 250mg $8 2026-05-28 Buy
aablocks AA0035N6 trans-4-Methoxy-3-buten-2-one 90%GC 51731-17-0 1g $10 2026-05-28 Buy
aablocks AA0035N6 trans-4-Methoxy-3-buten-2-one 90% 51731-17-0 5g $11 2026-05-28 Buy
Product number Packaging Price Buy
122068 10g $108 Buy
122068 50g $328 Buy
AA0035N6 250mg $8 Buy
AA0035N6 1g $10 Buy
AA0035N6 5g $11 Buy

4-Methoxy-3-buten-2-one Chemical Properties, Uses, Production

Uses

4-Methoxy-3-buten-2-one is a versatile four-carbon synthon; precursor to the Danishefsky diene; Diels-Alder dienophile; dipolarophile; electrophilic four-carbon synthon subject to conjugate addition at C-4 followed by elimination of the methoxide anion; its enolate is a nucleophilic four-carbon building block.

storage

4-Methoxy-3-buten-2-one may be harmful by inhalation, ingestion, or skin absorption; may cause skin and eye irritation; in addition to standard safety practice, mechanical exhaust is required. Do not breathe vapor. Store in refrigerator under nitrogen or argon.

4-Methoxy-3-buten-2-one Preparation Products And Raw materials

4-Methoxy-3-buten-2-one Suppliers

Global Suppliers ( 84)
Supplier Tel Email Country ProdList Advantage
Tianjin Rongshen Chemical Co., Ltd 18317763565; 18317763565 18317763565@163.com China 9878 58
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Syntechem Co.,Ltd info@syntechem.com China 12973 57
Sichuan Kulinan Technology Co., Ltd 400-1166-196 18981987031 cdhxsj@163.com China 11674 57
Anhui Shite Pharmaceutical Technology Co., LTD 086-21-50829787 13621628489 sales1@stepuppharm.com China 253 55
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9510 58
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 22497 55
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29985 65
Beijing Universal Century Technology Co., Ltd. hysj_bj.com China 3576 55
(3E)-4-Methoxy-3-buten-2-one trans-4-methoxy-3-buten-2-one (1-1-3) (E)-4-methoxy-3-buten-2-one TRANS-4-METHOXY-3-BUTEN-2-ONE, TECH., 90 % Trans 4-Methoxy Butenone TRANS-1-METHOXY-1-BUTEN-3-ONE TRANS-4-METHOXY-3-BUTEN-2-ONE trans-4-Methoxy-3-buten-2-one technical grade, 90% (3E)-4-Methoxybut-3-en-2-one Einecs 257-364-0 3-Buten-2-one,4-methoxy-, (3E)- 4-methoxy-3-butene-2-one trans-4-Methoxy-3-buten-2-one 4-Methoxy-3-buten-2-one 51731-17-0 C3 to C6 Carbonyl Compounds Building Blocks Organic Building Blocks Ketones C3 to C6 Carbonyl Compounds Ketones