SFTX-3.3
- CAS No.
- 141997-14-0
- Chemical Name:
- SFTX-3.3
- Synonyms
- SFTX-3.3;Pentanamide, 2-amino-5-[(aminoiminomethyl)amino]-N-[3-[(3-aminopropyl)amino]propyl]-, (2S)-
- CBNumber:
- CB7470758
- Molecular Formula:
- C12H29N7O
- Molecular Weight:
- 287.4
- MDL Number:
- MFCD01324663
- MOL File:
- 141997-14-0.mol
- MSDS File:
- SDS
SFTX-3.3 Chemical Properties, Uses, Production
Uses
sFTX-3.3 is a Ca2+ channel antagonist with IC50s of approximately 0.24 mM and 0.70 mM against P-type and N-type channels[1][2].
IC 50
P/Q-type calciumchannel: 0.24 mM (IC50); N-type calcium channel: 0.70 mM (IC50)
References
[1] Maria Elisa Calcagnotto, et al. An examination of calcium current function on heterotopic neurons in hippocampal slices from rats exposed to methylazoxymethanol. Epilepsia. 2003 Mar;44(3):315-21. DOI:10.1046/j.1528-1157.2003.41102.x
[2] T M Norris, et al. Block of high-threshold calcium channels by the synthetic polyamines sFTX-3.3 and FTX-3.3. Mol Pharmacol. 1996 Oct;50(4):939-46. PMID:8863840
[3] M Fatehi, et al. Polyamine FTX-3.3 and polyamine amide sFTX-3.3 inhibit presynaptic calcium currents and acetylcholine release at mouse motor nerve terminals. Neuropharmacology. 1997 Feb;36(2):185-94. DOI:10.1016/s0028-3908(96)00146-3
SFTX-3.3 Preparation Products And Raw materials
Raw materials
Preparation Products
SFTX-3.3 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |




