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4,4'-Dimethoxychalcone

CAS No.
2373-89-9
Chemical Name:
4,4'-Dimethoxychalcone
Synonyms
Nsc 87339;Ai3-25492;4,4'-Dimethoxychalcone;4,4'-Dimethoxychalcone;DIMETHOXYCHALCONE,4,4'-;4,4''-Dimethoxychalcone;4,4'-Dimethoxychalcone,99%;DIMETHOXYCHALCONE,4,4'-(RG);4,4'-DIMETHOXYBENZYLIDENEACETOPHENONE;4,4''-Dimethoxychalcone, 10 mM in DMSO
CBNumber:
CB7473401
Molecular Formula:
C17H16O3
Molecular Weight:
268.31
MDL Number:
MFCD00025815
MOL File:
2373-89-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:54:58

4,4'-Dimethoxychalcone Properties

Melting point 101°C
Boiling point 444.6±45.0 °C(Predicted)
Density 1.128±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: ≥ 250 mg/mL (931.76 mM)
form Solid
color Light yellow to yellow
BRN 1622293
CAS DataBase Reference 2373-89-9(CAS DataBase Reference)
FDA UNII 8KJ379G3P2

SAFETY

Risk and Safety Statements

Symbol(GHS)  Environment (GHS09)
GHS09
Signal word  Warning
Hazard statements  H400
Precautionary statements  P273-P391-P501
HS Code  29145090
NFPA 704
1
0 0

4,4'-Dimethoxychalcone price More Price(47)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S617237 4,4'-DIMETHOXYCHALCONE AldrichCPR 2373-89-9 1 unit $197 2026-04-30 Buy
Sigma-Aldrich S617237 4,4'-DIMETHOXYCHALCONE Aldrich 2373-89-9 25mg $179 2024-03-01 Buy
TCI Chemical B6793 4,4'-Dimethoxychalcone 2373-89-9 5G $71 2026-04-30 Buy
TCI Chemical B6793 4,4'-Dimethoxychalcone 2373-89-9 25G $246 2026-04-30 Buy
Biosynth FD54160 4,4'-Dimethoxychalcone 2373-89-9 5g $150 2026-06-04 Buy
Product number Packaging Price Buy
S617237 1 unit $197 Buy
S617237 25mg $179 Buy
B6793 5G $71 Buy
B6793 25G $246 Buy
FD54160 5g $150 Buy

4,4'-Dimethoxychalcone Chemical Properties, Uses, Production

Uses

4,4'-Dimethoxychalcone acts as a natural autophagy inducer with anti-ageing properties[1].

in vivo

The flavonoid 4,4'-Dimethoxychalcone acts as an anti-ageing compound with cardioprotective effects in mice and the potential to promote longevity across species[1].
4,4'-Dimethoxychalcone (100mg/kg; intraperitoneally) efficiently triggered autophagic flux in the heart and liver from wild type (WT) C57BL/6 mice[1].

Animal Model:6-week-old male wild type C57BL/6 or Atg4b-/- mice[1]
Dosage:100mg/kg
Administration:Injected intraperitoneally with a single
Result:Triggered autophagic flux in the heart and liver.

References

[1] Carmona-Gutierrez D, et al. The flavonoid 4,4'-dimethoxychalcone promotes autophagy-dependent longevity across species. Nat Commun. 2019 Feb 19;10(1):651. DOI:10.1038/s41467-019-08555-w

4,4'-Dimethoxychalcone Preparation Products And Raw materials

Global Suppliers ( 116)
Supplier Tel Email Country ProdList Advantage
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Wuhan ChemFaces Biochemical Co., Ltd. 18607101326 15172504745 aileen@chemfaces.com China 6904 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Yantai ShengKailun Chemical Technology Co., Ltd. 13356901049 3119594100@qq.com China 7964 55
Shanghai QiQiao Biological Technology Co., Ltd. 021-37653318 15221675714 515366396@qq.com China 2087 58

View Latest Price from 4,4'-Dimethoxychalcone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4,4'-Dimethoxychalcone pictures 2026-05-11 4,4'-Dimethoxychalcone
2373-89-9
$59.00-150.00 99.57% 10g TargetMol Chemicals Inc.

4,4'-Dimethoxychalcone Spectrum

1,3-BIS(4-METHOXYPHENYL)PROP-2-EN-1-ONE 2-Propen-1-one, 1,3-bis(4-methoxyphenyl)- Ai3-25492 Nsc 87339 4,4'-DIMETHOXYBENZYLIDENEACETOPHENONE DIMETHOXYCHALCONE,4,4'- (E)-1,3-BIS(4-METHOXYPHENYL)PROP-2-EN-1-ONE 4,4'-Dimethoxychalcone,99% DIMETHOXYCHALCONE,4,4'-(RG) JR-6811, (E)-1,3-bis(4-Methoxyphenyl)prop-2-en-1-one, 97% (E)-1,3-bis(4-methoxyphenyl)-2-propen-1-one 4,4' Dimethoxychalcone,natural,4,4'-Dimethoxychalcone,anti-ageing,inhibit,4,4'Dimethoxychalcone,Inhibitor,Autophagy 4,4'-Dimethoxychalcone 4,4''-Dimethoxychalcone 4,4''-Dimethoxychalcone, 10 mM in DMSO 4,4'-Dimethoxychalcone 2373-89-9 Chalcones