Benzyl 2-oxo-1,2-dihydropyridin-3-ylcarbamate
- CAS No.
- 147269-67-8
- Chemical Name:
- Benzyl 2-oxo-1,2-dihydropyridin-3-ylcarbamate
- Synonyms
- 3-(Cbz-amino)pyridin-2(1H)-one;benzyl 2-hydroxypyridin-3-ylcarbaMate;benzyl N-(2-oxo-1H-pyridin-3-yl)carbamate;Benzyl 2-oxo-1,2-dihydropyridin-3-ylcarbamate;benzyl N-(2-oxo-1,2-dihydropyridin-3-yl)carbaMate;2-Oxo-1,2-dihydropyridine-3-carbamic acid benzyl ester;(2-Oxo-1,2-dihydropyridin-3-yl)carbamic acid benzyl ester;BENZYL 2-OXO-1,2-DIHYDROPYRIDIN-3-YLCARBAMATE ISO 9001：2015 REACH;Carbamic acid, N-(1,2-dihydro-2-oxo-3-pyridinyl)-, phenylmethyl ester
- CBNumber:
- CB7474190
- Molecular Formula:
- C13H12N2O3
- Molecular Weight:
- 244.25
- MDL Number:
- MFCD07772020
- MOL File:
- 147269-67-8.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
Benzyl 2-oxo-1,2-dihydropyridin-3-ylcarbamate price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 295436 | Benzyl (2-oxo-1,2-dihydropyridin-3-yl)carbamate | 147269-67-8 | 1.00g | $82 | 2026-05-19 | Buy |
| Matrix Scientific | 295436 | Benzyl (2-oxo-1,2-dihydropyridin-3-yl)carbamate | 147269-67-8 | 5.00g | $298 | 2026-05-19 | Buy |
| Matrix Scientific | 295436 | Benzyl (2-oxo-1,2-dihydropyridin-3-yl)carbamate | 147269-67-8 | 10.00g | $539 | 2026-05-19 | Buy |
| Synthonix | B56754 | Benzyl (2-oxo-1,2-dihydropyridin-3-yl)carbamate 95+% | 147269-67-8 | 100mg | $16.64 | 2026-05-06 | Buy |
| Synthonix | B56754 | Benzyl (2-oxo-1,2-dihydropyridin-3-yl)carbamate 95+% | 147269-67-8 | 250mg | $35.24 | 2026-05-06 | Buy |
Benzyl 2-oxo-1,2-dihydropyridin-3-ylcarbamate Chemical Properties, Uses, Production
Synthesis
33630-99-8
501-53-1
147269-67-8
At room temperature, 3-aminopyridin-2(1H)-one (3.25 g, 29.5 mmol) and sodium carbonate (6.26 g, 59.0 mmol) were dissolved in tetrahydrofuran (100 mL), and benzyl chloroformate (5.27 mL, 36.9 mmol) was added slowly and dropwise. The reaction mixture was stirred at room temperature for 24 hours. Upon completion of the reaction, the reaction mixture was diluted with ethyl acetate (150 mL) and filtered through Celite. The filtrate was concentrated under reduced pressure to about 200 mL and subsequently washed with water (40 mL) and dried with anhydrous magnesium sulfate. It was again concentrated under reduced pressure to about 50 mL and the precipitated white solid (first product) was collected by filtration. The remaining filtrate was concentrated to near dryness under reduced pressure and the residue was stirred with ether (50 mL) and the insoluble white solid (second batch of product) was collected by diafiltration. The two batches of products were combined and dried under vacuum at 50 °C to afford the target compound (2-oxo-1,2-dihydropyridin-3-yl)carbamic acid benzyl ester (5.77 g, 23.62 mmol, 80% yield) as a white solid.
References
[1] ChemMedChem, 2011, vol. 6, # 7, p. 1228 - 1237
[2] Patent: WO2007/27729, 2007, A1. Location in patent: Page/Page column 39-40
[3] Patent: WO2015/89143, 2015, A1. Location in patent: Page/Page column 83; 84
[4] Journal of Medicinal Chemistry, 1994, vol. 37, # 19, p. 3090 - 3099
[5] Patent: US2007/287696, 2007, A1. Location in patent: Page/Page column 33
Benzyl 2-oxo-1,2-dihydropyridin-3-ylcarbamate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| EnliPharma Technology Co., Ltd | 0551-66399836 18955197623 | sales@enlipharma.com | China | 1875 | 55 |
| Hangzhou J&H Chemical Co., Ltd. | 0571-87396432 | sales@jhechem.com | China | 14905 | 59 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66028182 17714375163 | yftan@aikonchem.com | China | 16674 | 50 |
| Shanghai Tombiopharma Chemical Co. Ltd. | 13391076197 | tombiopharma@163.com | China | 4986 | 55 |
| Credit Asia Chemical Co., Ltd. | +86 (21) 61124340 | China | 9739 | 58 | |
| ChengDu TongChuangYuan Pharmaceutical Co.Ltd | 028-83379370 13880556291 | tcy@tcypharm.com | China | 8696 | 58 |
View Latest Price from Benzyl 2-oxo-1,2-dihydropyridin-3-ylcarbamate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-25 | BENZYL 2-OXO-1,2-DIHYDROPYRIDIN-3-YLCARBAMATE
147269-67-8
|
$1.10 | 1g | 99.0% min | 100 tons min | Shaanxi Dideu Medichem Co. Ltd | |
 |
2025-04-02 | Benzyl (2-oxo-1,2-dihydropyridin-3-yl)carbamate
147269-67-8
|
1g | 98% | 1kg | NewCan Biotech Limited |
-
- BENZYL 2-OXO-1,2-DIHYDROPYRIDIN-3-YLCARBAMATE
147269-67-8
- $1.10
- 99.0% min
- Shaanxi Dideu Medichem Co. Ltd
-
- Benzyl (2-oxo-1,2-dihydropyridin-3-yl)carbamate
147269-67-8
- 98%
- NewCan Biotech Limited
