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CLK inhibitor T3 (T3)

CLK inhibitor T3 (T3) Structure
CLK inhibitor T3 (T3) structure
CAS No.
2109805-56-1
Chemical Name:
CLK inhibitor T3 (T3)
Synonyms
T3-CLK;CLK-IN-T3;CLK inhibitor T3 (T3);CLK-IN-T3, 10 mM in DMSO;T3 CLK New;4-[1,1-Dimethyl-2-(4-methyl-1-piperazinyl)-2-oxoethyl]-N-[6-(4-pyridinyl)imidazo[1,2-a]pyridin-2-yl]benzamide;Benzamide, 4-[1,1-dimethyl-2-(4-methyl-1-piperazinyl)-2-oxoethyl]-N-[6-(4-pyridinyl)imidazo[1,2-a]pyridin-2-yl]-;CDC-like,Dual specificity tyrosine phosphorylation regulated kinase,inhibit,Dual specificity tyrosine regulated kinase,stable,anti-cancer,DYRK,CLK,kinase,CDK,CLK-IN-T-3,CLKINT3,DYRK1A,Inhibitor,activity,CLK IN T3,DYRK1B,Cyclin dependent kinase
CBNumber:
CB74844652
Molecular Formula:
C28H30N6O2
Molecular Weight:
482.58
MDL Number:
MFCD31689325
MOL File:
2109805-56-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-08-12 19:01:03
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CLK inhibitor T3 (T3) Properties

Density 1.25±0.1 g/cm3(Predicted)
storage temp. room temp
solubility DMSO: 2mg/mL, clear (warmed)
form Solid
pka 4.70±0.46(Predicted)
color Off-white to light yellow
InChIKey IEFFSHLHNYVSEF-UHFFFAOYSA-N
SMILES C(NC1=CN2C(=N1)C=CC(C1C=CN=CC=1)=C2)(=O)C1=CC=C(C(C)(C)C(N2CCN(C)CC2)=O)C=C1
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

WGK Germany  WGK 3
Storage Class 11 - Combustible Solids

CLK inhibitor T3 (T3) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 41309 T3-CLK ≥98% 2109805-56-1 5mg $127 2026-04-30 Buy
Cayman Chemical 41309 T3-CLK ≥98% 2109805-56-1 10mg $241 2026-04-30 Buy
Cayman Chemical 41309 T3-CLK ≥98% 2109805-56-1 50mg $1012 2026-04-30 Buy
Cayman Chemical 41309 T3-CLK ≥98% 2109805-56-1 100mg $1392 2026-04-30 Buy
Biosynth JJD80556 CLK-IN-T3 2109805-56-1 50mg $5461 2026-06-04 Buy
Product number Packaging Price Buy
41309 5mg $127 Buy
41309 10mg $241 Buy
41309 50mg $1012 Buy
41309 100mg $1392 Buy
JJD80556 50mg $5461 Buy

CLK inhibitor T3 (T3) Chemical Properties, Uses, Production

Uses

CLK-IN-T3 is a high potent, selective, and stable CDC-like kinase (CLK) inhibitor with IC50s of 0.67 nM, 15 nM, and 110 nM for CLK1, CLK2, and CLK3 protein kinases, respectively. CLK-IN-T3 has anti-cancer activity[1].

Biological Activity

T3-CLK (T3) is a cell permeable, highly potent and selective cell-base stable inhibitor of CDC-like kinase (CLK) th at exhibits dose-dependent alternative splicing effects in HCT116 colorectal cancer cells. T3-CLK increases conjoined gene (CG) transcription.

IC 50

CLK1: 0.67 nM (IC50); CLK2: 15 nM (IC50); CLK3: 110 nM (IC50); DYRK1A: 260 nM (IC50); DYRK1B: 230 nM (IC50)

References

[1] Funnell T, et al. CLK-dependent exon recognition and conjoined gene formation revealed with a novel smallmolecule inhibitor. Nat Commun. 2017 Feb 23;8(1):7. DOI:10.1038/s41467-016-0008-7

CLK inhibitor T3 (T3) Preparation Products And Raw materials

Raw materials

Preparation Products

CLK inhibitor T3 (T3) Suppliers

Global Suppliers ( 43)
Supplier Tel Email Country ProdList Advantage
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
Shanghai Chaolan Chemical Technology Center QQ：65489617 13301690235 Sales@ATKchemical.com China 9699 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
InvivoChem +1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6378 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 15317229551 15151849396@163.com China 959 58
Supplier Advantage
Nanjing Chemlin Chemical Co., Ltd 64
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60
ShangHai Biochempartner Co.,Ltd 62
Shanghai Chaolan Chemical Technology Center 58
BOC Sciences 58
TargetMol Chemicals Inc. 58
InvivoChem 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 58

View Latest Price from CLK inhibitor T3 (T3) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
CLK inhibitor T3 (T3) pictures 2026-08-12 CLK inhibitor T3 (T3)
2109805-56-1
 1KG 98% 1000kg Shaanxi Dideu New Materials Co. Ltd
CLK-IN-T3 pictures 2026-07-27 CLK-IN-T3
2109805-56-1
 $42.00-172.00 99.61% 10g TargetMol Chemicals Inc.
  • CLK-IN-T3 pictures
  • CLK-IN-T3
    2109805-56-1
  • $42.00-172.00
  • 99.61%
  • TargetMol Chemicals Inc.

CLK inhibitor T3 (T3) Spectrum

CLK inhibitor T3 (T3)(2109805-56-1)1HNMR

2109805-56-1 (CLK inhibitor T3 (T3)) Related Search:

NA Benzamide, 4-(1,1-dimethylethyl)-N-imidazo[1,2-a]pyridin-2-yl- CLK inhibitor T3 (T3) Benzamide, N-[6-[3,5-bis(1,1-dimethylethyl)phenyl]imidazo[1,2-a]pyridin-2-yl]-4-[1,1-dimethyl-2-(4-methyl-1-piperazinyl)-2-oxoethyl]- SGC-CLK-1
GW806742X

1of2

CLK inhibitor T3 (T3) CLK-IN-T3 Benzamide, 4-[1,1-dimethyl-2-(4-methyl-1-piperazinyl)-2-oxoethyl]-N-[6-(4-pyridinyl)imidazo[1,2-a]pyridin-2-yl]- T3-CLK CDC-like,Dual specificity tyrosine phosphorylation regulated kinase,inhibit,Dual specificity tyrosine regulated kinase,stable,anti-cancer,DYRK,CLK,kinase,CDK,CLK-IN-T-3,CLKINT3,DYRK1A,Inhibitor,activity,CLK IN T3,DYRK1B,Cyclin dependent kinase T3 CLK New CLK-IN-T3, 10 mM in DMSO 4-[1,1-Dimethyl-2-(4-methyl-1-piperazinyl)-2-oxoethyl]-N-[6-(4-pyridinyl)imidazo[1,2-a]pyridin-2-yl]benzamide 2109805-56-1 C28H30N6O2