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ChemicalBook >> CAS DataBase List >>N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,5-dimethoxybenzamide trifluoroacetate

N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,5-dimethoxybenzamide trifluoroacetate

N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,5-dimethoxybenzamide trifluoroacetate Structure
N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,5-dimethoxybenzamide trifluoroacetate structure
CAS No.
1336913-03-1
Chemical Name:
N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,5-dimethoxybenzamide trifluoroacetate
Synonyms
PSEM 89S;PSEM 89S TFA;PSEM 89S TFA, 10 mM in DMSO;(S)-2,5-Dimethoxy-N-(quinuclidin-3-yl)benzamide 2,2,2-trifluoroacetate;N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,5-dimethoxybenzamide trifluoroacetate;PSEM 89S TFA,GlyR,Ion,inhibit,nAChR,channels,L141F,PSAM,Q79G,PSEM 89S,Nicotinic acetylcholine receptors,Inhibitor
CBNumber:
CB74902802
Molecular Formula:
C18H23F3N2O5
Molecular Weight:
404.39
MDL Number:
MFCD31689251
MOL File:
1336913-03-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-22 15:57:46
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N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,5-dimethoxybenzamide trifluoroacetate Properties

storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Soluble in DMSO
form Solid
color Off-white to light yellow

N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,5-dimethoxybenzamide trifluoroacetate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth LDC91303 PSEM 89S 1336913-03-1 25mg $1034.5 2026-06-04 Buy
Biosynth LDC91303 PSEM 89S 1336913-03-1 50mg $1439.5 2026-06-04 Buy
Biosynth LDC91303 PSEM 89S 1336913-03-1 100mg $2302 2026-06-04 Buy
ChemScene CS-0044172 PSEM 89S TFA 99.85% 1336913-03-1 5mg $130 2026-06-04 Buy
ChemScene CS-0044172 PSEM 89S TFA 99.85% 1336913-03-1 10mg $206 2026-06-04 Buy
Product number Packaging Price Buy
LDC91303 25mg $1034.5 Buy
LDC91303 50mg $1439.5 Buy
LDC91303 100mg $2302 Buy
CS-0044172 5mg $130 Buy
CS-0044172 10mg $206 Buy

N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,5-dimethoxybenzamide trifluoroacetate Chemical Properties, Uses, Production

Uses

PSEM 89S TFA is a selective and brain penetrant agonists for the resulting ion channels. PSEM 89S TFA is orthogonally selective for Q79G and L141F, respectively[1].

in vivo

PSEM 89S strongly reduces photostimulation-evoked feeding in mice expressing PSAML141F,Y115F- glycine receptor (GlyR) (30 mg/kg) but not in mice expressing only channelrhodopsin-2 (ChR2) (50 mg/kg)[1].
PSEM 89S (30 mg/kg) shows good brain penetrance in mice after minimally invasive intraperitoneal administration[1].

Animal Model:Male Agrp-cre mice (3-6 weeks)[1]
Dosage:30 mg/kg
Administration:I.p. administration
Result:Almost completely suppressed fos (a marker of neuron activation) in ChR2-expressing neurons.
Animal Model:C57BL/6 mice[1]
Dosage:30 mg/kg (Pharmacokinetic Analysis)
Administration:I.p. administration
Result:Rised rapidly in serum and brain, and was mostly cleared from both compartments in 1 h.

storage

Store at -20°C

References

[1] Christopher JM, et, al. Chemical and genetic engineering of selective ion channel-ligand interactions. Science. 2011 Sep 2; 333(6047): 1292-6. DOI:10.1126/science.1206606

N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,5-dimethoxybenzamide trifluoroacetate Preparation Products And Raw materials

Raw materials

Preparation Products

N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,5-dimethoxybenzamide trifluoroacetate Suppliers

Global Suppliers ( 28)
Supplier Tel Email Country ProdList Advantage
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 9777 55
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Yangzhou modier Electronic Materials Co., Ltd 13761402923 19975033992 market@modeltemol.com China 7851 58
Zhejiang Huida Biotech Co., LTD 0571-89903022 18679456698 zilong@hizyme.com China 8001 58
cjbscvictory 13348960310 13348960310 3003867561@qq.com China 10233 58
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 5000 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
Supplier Advantage
Shanghai YuanYe Biotechnology Co., Ltd. 60
Tianjin Kailiqi Biotechnology Co., Ltd. 55
ShangHai Biochempartner Co.,Ltd 62
Shanghai Hongye Biotechnology Co. Ltd 58
TargetMol Chemicals Inc. 58
Yangzhou modier Electronic Materials Co., Ltd 58
Zhejiang Huida Biotech Co., LTD 58
cjbscvictory 58
Jinan Jiuli Biotechnology Co. , Ltd. 58
Beijing Jin Ming Biotechnology Co., Ltd. 58

View Latest Price from N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,5-dimethoxybenzamide trifluoroacetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PSEM 89S TFA pictures 2026-07-21 PSEM 89S TFA
1336913-03-1
 $41.00-125.00 99.98% 10g TargetMol Chemicals Inc.
  • PSEM 89S TFA pictures
  • PSEM 89S TFA
    1336913-03-1
  • $41.00-125.00
  • 99.98%
  • TargetMol Chemicals Inc.

N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,5-dimethoxybenzamide trifluoroacetate Spectrum

N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,5-dimethoxybenzamide trifluoroacetate(1336913-03-1)1HNMR

1336913-03-1 (N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,5-dimethoxybenzamide trifluoroacetate) Related Search:

Flecainide 4-Hydroxyflecainide (S)-Flecainide 1H-Isoindole-1,3(2H)-dione, 4-(3-aminopropoxy)-2-(2,6-dioxo-3-piperidinyl)-, 2,2,2-trifluoroacetate (1:1) Benzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-2-methoxy-
N-[2-(piperidin-1-yl)ethyl]-2,5-bis(2,2,2-trifluoroethoxy)benzamide

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N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,5-dimethoxybenzamide trifluoroacetate PSEM 89S TFA PSEM 89S (S)-2,5-Dimethoxy-N-(quinuclidin-3-yl)benzamide 2,2,2-trifluoroacetate PSEM 89S TFA,GlyR,Ion,inhibit,nAChR,channels,L141F,PSAM,Q79G,PSEM 89S,Nicotinic acetylcholine receptors,Inhibitor PSEM 89S TFA, 10 mM in DMSO 1336913-03-1