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5'-Fluoro-2'-hydroxy-3'-nitro-

CAS No.
70978-39-1
Chemical Name:
5'-Fluoro-2'-hydroxy-3'-nitro-
Synonyms
5'-Fluoro-2'-hydroxy-3'-nitro-;5'-fluoro-2'-hydroxy-3'-nitroacetopheone;5'-FLUORO-2'-HYDROXY-3'-NITROACETOPHENONE;Ethanone, 1-(5-fluoro-2-hydroxy-3-nitrophenyl)-;1-(5-Fluoro-2-hydroxy-3-nitrophenyl)ethan-1-one;5′-Fluoro-2′-hydroxy-3′-nitroacetophenone, CAS 70978-39-1;JRH-01022, 1-(5-Fluoro-2-hydroxy-3-nitrophenyl)ethanone, 97%
CBNumber:
CB7499702
Molecular Formula:
C8H6FNO4
Molecular Weight:
199.14
MDL Number:
MFCD03094007
MOL File:
70978-39-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:54:59

5'-Fluoro-2'-hydroxy-3'-nitro- Properties

Melting point 87-90 °C (lit.)
Boiling point 240.9±35.0 °C(Predicted)
Density 1.470±0.06 g/cm3(Predicted)
pka 6.96±0.38(Predicted)
InChI 1S/C8H6FNO4/c1-4(11)6-2-5(9)3-7(8(6)12)10(13)14/h2-3,12H,1H3
InChIKey YVTPUCHIOSGVSH-UHFFFAOYSA-N
SMILES CC(=O)c1cc(F)cc(c1O)[N+]([O-])=O
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

5'-Fluoro-2'-hydroxy-3'-nitro- price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 543780 5′-Fluoro-2′-hydroxy-3′-nitroacetophenone 98% 70978-39-1 1g $20.9 2026-04-30 Buy
Usbiological 277957 1-(5-Fluoro-2-hydroxy-3-nitrophenyl)ethanone Asreported 70978-39-1 500mg $333 2026-06-03 Buy
Usbiological 277957 1-(5-Fluoro-2-hydroxy-3-nitrophenyl)ethanone Asreported 70978-39-1 1g $470 2026-06-03 Buy
Usbiological 277957 1-(5-Fluoro-2-hydroxy-3-nitrophenyl)ethanone Asreported 70978-39-1 2g $632 2026-06-03 Buy
Usbiological 277957 1-(5-Fluoro-2-hydroxy-3-nitrophenyl)ethanone Asreported 70978-39-1 5g $1115 2026-06-03 Buy
Product number Packaging Price Buy
543780 1g $20.9 Buy
277957 500mg $333 Buy
277957 1g $470 Buy
277957 2g $632 Buy
277957 5g $1115 Buy

5'-Fluoro-2'-hydroxy-3'-nitro- Chemical Properties,Uses,Production

Uses

5′-Fluoro-2′-hydroxy-3′-nitroacetophenone may be used to prepare 1-(3-amino-5-fluoro-2-hydroxyphenyl)ethanone via catalytic hydrogenation.

Preparation

Preparation by nitration of 5-fluoro-2-hydroxy-acetophenone with nitric acid (d = 1.42) in concentrated sulfuric acid between 15° and 5° (46%).

General Description

5′-Fluoro-2′-hydroxy-3′-nitroacetophenone, also known as 1-(5-fluoro-2-hydroxy-3-nitrophenyl)ethanone, is an aromatic hydroxy ketone. It can be synthesized from 5-fluoro-2-hydroxy-acetophenone via nitration.

5'-Fluoro-2'-hydroxy-3'-nitro- Preparation Products And Raw materials

Raw materials

Preparation Products

5'-Fluoro-2'-hydroxy-3'-nitro- Suppliers

Global( 37)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Beijing Eternalchem Co,. Ltd. 010-59484199 18611897322;18611897322; sales@eternalchem.com China 1993 60
Tianjin heowns Biochemical Technology Co., Ltd. 400 638 7771 sales@heowns.com China 14412 57
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Quzhou AMK BioTech Co., Ltd 0570-3081766 18357083060 sales@qzamkbio.com China 1199 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Aikon International Limited 025-58859352 19370895928 sales01@aikonchem.com China 15078 58
JRH-01022, 1-(5-Fluoro-2-hydroxy-3-nitrophenyl)ethanone, 97% 5'-fluoro-2'-hydroxy-3'-nitroacetopheone 1-(5-Fluoro-2-hydroxy-3-nitrophenyl)ethan-1-one Ethanone, 1-(5-fluoro-2-hydroxy-3-nitrophenyl)- 5'-FLUORO-2'-HYDROXY-3'-NITROACETOPHENONE 5′-Fluoro-2′-hydroxy-3′-nitroacetophenone, CAS 70978-39-1 5'-Fluoro-2'-hydroxy-3'-nitro- 70978-39-1 FC6H2OHNO2COCH3 C7 to C8 Carbonyl Compounds Ketones