Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>Acetic acid, 2-[[4-[(1S)-1-[[(4,5-dichloro-1,6-dimethyl-1H-indol-2-yl)carbonyl]amino]-2-hydroxyethyl]phenyl]sulfonyl]-

Acetic acid, 2-[[4-[(1S)-1-[[(4,5-dichloro-1,6-dimethyl-1H-indol-2-yl)carbonyl]amino]-2-hydroxyethyl]phenyl]sulfonyl]-

Acetic acid, 2-[[4-[(1S)-1-[[(4,5-dichloro-1,6-dimethyl-1H-indol-2-yl)carbonyl]amino]-2-hydroxyethyl]phenyl]sulfonyl]- Structure
Acetic acid, 2-[[4-[(1S)-1-[[(4,5-dichloro-1,6-dimethyl-1H-indol-2-yl)carbonyl]amino]-2-hydroxyethyl]phenyl]sulfonyl]- structure
CAS No.
2244452-09-1
Chemical Name:
Acetic acid, 2-[[4-[(1S)-1-[[(4,5-dichloro-1,6-dimethyl-1H-indol-2-yl)carbonyl]amino]-2-hydroxyethyl]phenyl]sulfonyl]-
Synonyms
BI-4924;BI4924,BI 4924;2-{4-[(1S)-1-[(4,5-dichloro-1,6-dimethyl-1H-indol-2-yl)formamido]-2-hydroxyethyl]benzenesulfonyl}acetic acid;Acetic acid, 2-[[4-[(1S)-1-[[(4,5-dichloro-1,6-dimethyl-1H-indol-2-yl)carbonyl]amino]-2-hydroxyethyl]phenyl]sulfonyl]-
CBNumber:
CB75482154
Molecular Formula:
C21H20Cl2N2O6S
Molecular Weight:
499.36
MDL Number:
MFCD32197236
MOL File:
2244452-09-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:55
Request For Quotation

Acetic acid, 2-[[4-[(1S)-1-[[(4,5-dichloro-1,6-dimethyl-1H-indol-2-yl)carbonyl]amino]-2-hydroxyethyl]phenyl]sulfonyl]- Properties

Boiling point 860.6±65.0 °C(Predicted)
Density 1.52±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form Solid
pka 2.51±0.10(Predicted)
color Off-white to yellow

Acetic acid, 2-[[4-[(1S)-1-[[(4,5-dichloro-1,6-dimethyl-1H-indol-2-yl)carbonyl]amino]-2-hydroxyethyl]phenyl]sulfonyl]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0101055 BI-4924 99.55% 2244452-09-1 1mg $282 2026-06-04 Buy
ChemScene CS-0101055 BI-4924 99.55% 2244452-09-1 5mg $444 2026-06-04 Buy
ChemScene CS-0101055 BI-4924 99.55% 2244452-09-1 10mg $710 2026-06-04 Buy
ChemScene CS-0101055 BI-4924 99.55% 2244452-09-1 25mg $1419 2026-06-04 Buy
ChemScene CS-0101055 BI-4924 99.55% 2244452-09-1 50mg $2275 2026-06-04 Buy
Product number Packaging Price Buy
CS-0101055 1mg $282 Buy
CS-0101055 5mg $444 Buy
CS-0101055 10mg $710 Buy
CS-0101055 25mg $1419 Buy
CS-0101055 50mg $2275 Buy

Acetic acid, 2-[[4-[(1S)-1-[[(4,5-dichloro-1,6-dimethyl-1H-indol-2-yl)carbonyl]amino]-2-hydroxyethyl]phenyl]sulfonyl]- Chemical Properties,Uses,Production

Uses

BI-4924 is a lipophilic, highly plasma protein bound selective phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50=3 nM) with excellent microsomal, as well as hepatocytic stability. Intracellular trapping of BI-4924 disrupts serine biosynthesis with an IC50 of 2200 nM at 72 h[1].

References

[1] Weinstabl H, et al. Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) Inhibitor BI-4924 Disrupts Serine Biosynthesis. J Med Chem. 2019 Jul 31. DOI:10.1021/acs.jmedchem.9b00718

Acetic acid, 2-[[4-[(1S)-1-[[(4,5-dichloro-1,6-dimethyl-1H-indol-2-yl)carbonyl]amino]-2-hydroxyethyl]phenyl]sulfonyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

Acetic acid, 2-[[4-[(1S)-1-[[(4,5-dichloro-1,6-dimethyl-1H-indol-2-yl)carbonyl]amino]-2-hydroxyethyl]phenyl]sulfonyl]- Suppliers

Global( 19)Suppliers
Supplier Tel Email Country ProdList Advantage
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3493 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4861 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
ANHUI WITOP BIOTECH CO., LTD +8618071025641 eric@witopchemical.com China 23504 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
https://hanhongsci.com/ 021-54306202 18917919676 info@hanhongsci.com China 29982 58
Anqing YanZhi Pharma Discovery Co.,Ltd. 18055651951 2272561977@qq.com China 442 58
Supplier Advantage
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
Shanghai Lollane Biological Technology Co.,Ltd. 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
TargetMol Chemicals Inc. 58
ANHUI WITOP BIOTECH CO., LTD 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
https://hanhongsci.com/ 58
Anqing YanZhi Pharma Discovery Co.,Ltd. 58

2244452-09-1(Acetic acid, 2-[[4-[(1S)-1-[[(4,5-dichloro-1,6-dimethyl-1H-indol-2-yl)carbonyl]amino]-2-hydroxyethyl]phenyl]sulfonyl]-)Related Search:

PHGDH-IN-2 PHGDH-IN-6 Benzamide, 4-[[(3-acetylphenyl)amino]sulfonyl]-N-[4-(3-fluorophenyl)-2-thiazolyl]- 4-[[4-(1H-benzimidazol-2-yl)phenyl]amino]-4-keto-butyric acid PHGDH-inactive
BI-4916

1of2

Acetic acid, 2-[[4-[(1S)-1-[[(4,5-dichloro-1,6-dimethyl-1H-indol-2-yl)carbonyl]amino]-2-hydroxyethyl]phenyl]sulfonyl]- BI-4924 BI4924,BI 4924 2-{4-[(1S)-1-[(4,5-dichloro-1,6-dimethyl-1H-indol-2-yl)formamido]-2-hydroxyethyl]benzenesulfonyl}acetic acid 2244452-09-1 C21H20Cl2N2O6S APIs