ChemicalBook >> CAS DataBase List >>MC-VC-PABC-DNA31

MC-VC-PABC-DNA31

CAS No.
1639352-03-6
Chemical Name:
MC-VC-PABC-DNA31
Synonyms
MC-VC-PABC-DNA31;Rifamycin VIII, 1',4-didehydro-5'-[4-[[[[4-[[N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-L-ornithyl]amino]phenyl]methoxy]carbonyl]amino]-1-piperidinyl]-1,4-dihydro-3'-hydroxy-1-oxo-
CBNumber:
CB75540384
Molecular Formula:
C77H96N10O21
Molecular Weight:
1497.64
MDL Number:
MFCD32197308
MOL File:
1639352-03-6.mol
MSDS File:
SDS
Last updated:2025-04-18 09:52:43

MC-VC-PABC-DNA31 Properties

Density 1.42±0.1 g/cm3(Predicted)
pka 4.28±0.70(Predicted)
form Solid
color Light blue to blue

MC-VC-PABC-DNA31 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0101955 MC-VC-PABC-DNA31 98.71% 1639352-03-6 5mg $422 2026-06-04 Buy
ChemScene CS-0101955 MC-VC-PABC-DNA31 98.71% 1639352-03-6 10mg $677 2026-06-04 Buy
ChemScene CS-0101955 MC-VC-PABC-DNA31 98.71% 1639352-03-6 25mg $1354 2026-06-04 Buy
ChemScene CS-0101955 MC-VC-PABC-DNA31 98.71% 1639352-03-6 50mg $2167 2026-06-04 Buy
ChemScene CS-0101955 MC-VC-PABC-DNA31 98.71% 1639352-03-6 100mg $3467 2026-06-04 Buy
Product number Packaging Price Buy
CS-0101955 5mg $422 Buy
CS-0101955 10mg $677 Buy
CS-0101955 25mg $1354 Buy
CS-0101955 50mg $2167 Buy
CS-0101955 100mg $3467 Buy

MC-VC-PABC-DNA31 Chemical Properties, Uses, Production

Uses

MC-VC-PABC-DNA31 is a agent-linker conjugate for ADC with potent antitumor activity by using DNA31 (a potent RNA polymerase inhibitor), linked via the ADC linker MC-VC-PABC.

IC 50

Traditional Cytotoxic Agents

References

[1] Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119. DOI:10.1038/nchem.2635

MC-VC-PABC-DNA31 Preparation Products And Raw materials

Raw materials

Preparation Products

MC-VC-PABC-DNA31 Suppliers

Global Suppliers ( 9)
Supplier Tel Email Country ProdList Advantage
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9718 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Shanghai Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 811 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 4000862158 18117107507 vip@med-life.cn China 4999 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Henan Rane Chemical Co., Ltd. +86-18738066252 info@ranechem.com China 2999 58
Zhejiang Huida Biotech Co., Ltd. 0571-89903022 18679456698 zilong@hizyme.com China 7853 58
ChemExpress +86-021-58950125 info@chemexpress.com China 790 58
MC-VC-PABC-DNA31 Rifamycin VIII, 1',4-didehydro-5'-[4-[[[[4-[[N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-L-ornithyl]amino]phenyl]methoxy]carbonyl]amino]-1-piperidinyl]-1,4-dihydro-3'-hydroxy-1-oxo- 1639352-03-6