GRAYANOTOXIN III
- CAS No.
- 4678-45-9
- Chemical Name:
- GRAYANOTOXIN III
- Synonyms
- andromedol;GRAYANOTOXIN III;deacylasebotoxini;deacetylandromedotoxin;Grayanotoxin III Hemi(ethyl acetate);GRAYANOTOXIN 3.1/2 ETHYL ACETATE ADDUCT;(14R)-Grayanotoxane-3β,5,6β,10,14,16-hexol;GRAYANOTOXIN III HEMI(ETHYL ACETATE) ADDUCT;Grayanotoxane-3,5,6,10,14,16-hexol,(3b,6b,14R)-;Grayanotoxane-3,5,6,10,14,16-hexol, (3β,6β,14R)-
- CBNumber:
- CB7674097
- Molecular Formula:
- C20H34O6
- Molecular Weight:
- 370.48
- MDL Number:
- MFCD01319138
- MOL File:
- 4678-45-9.mol
- MSDS File:
- SDS
| Melting point | 218 °C (decomp) |
|---|---|
| Boiling point | 552.6±50.0 °C(Predicted) |
| Density | 1.36±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility |
Acetonitrile: Slightly Soluble: 0.1-1 mg/ml Water: Slightly Soluble: 0.1-1 mg/ml |
| pka | 13.79±0.70(Predicted) |
| FDA UNII | ZKR09NT58C |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301-H315-H319-H331-H311 |
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501-P264-P280-P305+P351+P338-P337+P313P-P280-P302+P352-P312-P322-P361-P363-P405-P501-P264-P280-P302+P352-P321-P332+P313-P362-P261-P271-P304+P340-P311-P321-P403+P233-P405-P501 |
| Hazard Codes | T |
| Risk Statements | 23/24/25-36/38 |
| Safety Statements | 22-26-36/37/39-45 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | PB9190000 |
| HazardClass | 6.1(a) |
| PackingGroup | I |
| Toxicity | LD50 i.p. in mice: 0.84 mg/kg (Hikino, 1976) |
GRAYANOTOXIN III Chemical Properties, Uses, Production
Description
Grayanotoxin III (GTX-III) is a diterpene toxin that has been found in R. ponticum nectar, a component of mad honey.1 In vivo, GTX-III (0.1 and 0.25 mg/kg) induces salivation, emesis, and hind paw paralysis in mice.2 It is lethal to mice (LD50 = 0.84 mg/kg).WARNING This product is not for human or veterinary use.
Hazard
A poison
References
[1] ARZUM BAHAR KURTOGLU Gulsun A E Recep Yavuz. Characterisation and fate of grayanatoxins in mad honey produced from Rhododendron ponticum nectar[J]. Food Chemistry, 2014, 161: Pages 47-52. DOI: 10.1016/j.foodchem.2014.03.127
[2] T. OHGAKI . Preventive action of quisqualic acid against grayanotoxin-induced suppression of locomotor activity in mice[J]. Neuropharmacology, 1988, 27 10: Pages 1045-1053. DOI: 10.1016/0028-3908(88)90066-4
GRAYANOTOXIN III Preparation Products And Raw materials
Raw materials
Preparation Products
GRAYANOTOXIN III Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| AFINE CHEMICALS LIMITED | +86-571-85134551 +86-18958018566 | info@afinechem.com | China | 15030 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| Cato Research Chemicals Inc. | 81960175 18933936954 | 2853283383@qq.com | China | 11418 | 58 |
| Chengdu Peter-like Biotechnology Co., Ltd. | 028-81700200 13308200041 | 2851167782@qq.com | China | 10763 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53736 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
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