5,6-Dehydroarachidonic acid
- CAS No.
- 58688-54-3
- Chemical Name:
- 5,6-Dehydroarachidonic acid
- Synonyms
- 5,6-dehydro aa;5,6-Dehydroarachidonic acid;GIOQWSLKUVKKAO-QNEBEIHSSA-N;eicosa-8,11,14-trien-5-ynoic acid;8Z,11Z,14Z-EICOSATRIEN-5-YNOIC ACID;CIS-8,11,14-EICOSATRIEN-5-YNOIC ACID;8,11,14-Eicosatrien-5-ynoic acid, (8Z,11Z,14Z)-;5,6-dehydro AA, cis-8,11,14-Eicosatrien-5-ynoic acid;5,6 dehydro Arachidonic Acid,5,6dehydro Arachidonic Acid
- CBNumber:
- CB7674299
- Molecular Formula:
- C20H30O2
- Molecular Weight:
- 302.45
- MDL Number:
- MFCD00065715
- MOL File:
- 58688-54-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 444.707±45.00 °C(Press: 760.00 Torr)(predicted) |
|---|---|
| Density | 0.953±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| Flash point | 17 °C |
| storage temp. | −20°C |
| solubility | 0.15 M Tris-HCl pH 8.5: >1 mg/ml (from Oleic Acid); DMF: >100 mg/ml (from Oleic Acid); DMSO: >100 mg/ml (from Oleic Acid); Ethanol: >100 mg/ml (from Oleic Acid); PBS pH 7.2: <100 μg/ml (from Oleic Acid) |
| form | ethanol solution |
| pka | 4.615±0.10(predicted) |
| InChI | 1S/C20H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12- |
| InChIKey | GIOQWSLKUVKKAO-QNEBEIHSSA-N |
| SMILES | CCCCC\C=C/C\C=C/C\C=C/CC#CCCCC(O)=O |
| UNSPSC Code | 12352211 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H319 | |||||||||
| Precautionary statements | P210-P305+P351+P338 | |||||||||
| Hazard Codes | F | |||||||||
| Risk Statements | 11-16 | |||||||||
| Safety Statements | 16-7 | |||||||||
| RIDADR | UN 1170 3/PG 2 | |||||||||
| WGK Germany | 1 | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Flam. Liq. 2 |
|||||||||
| NFPA 704 |
|
5,6-Dehydroarachidonic acid price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D2154 | 5,6-Dehydroarachidonic acid ≥98%, ethanol solution | 58688-54-3 | 100μg | $534 | 2026-04-30 | Buy |
| Sigma-Aldrich | D2154 | 5,6-Dehydroarachidonic acid ≥98%, ethanol solution | 58688-54-3 | 25μg | $249 | 2023-01-07 | Buy |
| Cayman Chemical | 90020 | 5,6-dehydro Arachidonic Acid ≥98% | 58688-54-3 | 25μg | $108 | 2026-04-30 | Buy |
| Cayman Chemical | 90020 | 5,6-dehydro Arachidonic Acid ≥98% | 58688-54-3 | 50μg | $205 | 2026-04-30 | Buy |
| Cayman Chemical | 90020 | 5,6-dehydro Arachidonic Acid ≥98% | 58688-54-3 | 100μg | $387 | 2026-04-30 | Buy |
5,6-Dehydroarachidonic acid Chemical Properties, Uses, Production
Uses
5,6-Dehydroarachidonic acid is a 5-lipoxygenase (Lipoxygenase) inhibitor that inhibits the biosynthesis of leukotrienes. However, 5,6-Dehydroarachidonic acid had no effect on vascular cell proliferation[1][2][3].
Definition
ChEBI: 5,6-dehydro Arachidonic Acid is a long-chain fatty acid.
Biological Activity
Inhibits 5-lipoxygenase of guinea pig leukocytes with an IC50 of 10 μM. In extracts of r at basophilic leukemia cells preincubated with 5,6-dehydro AA, the Ki for the conversion of arachidonic acid to 5-HPETE is 15 μM.
References
[1] Sok DE, et al. Inhibition of leukotriene biosynthesis by acetylenic analogs. Biochem Biophys Res Commun. 1982 Jul 16;107(1):101-8. DOI:10.1016/0006-291x(82)91675-8
[2] Dethlefsen SM, et al. Arachidonic acid metabolites in bFGF-, PDGF-, and serum-stimulated vascular cell growth. Exp Cell Res. 1994 Jun;212(2):262-73. DOI:10.1006/excr.1994.1142
[3] Corey E J, et al. Synthesis of three potential inhibitors of the biosynthesis of leukotrienes A–E[J]. Tetrahedron Letters, 1980, 21(44): 4243-4246.
5,6-Dehydroarachidonic acid Preparation Products And Raw materials
Raw materials
Preparation Products
5,6-Dehydroarachidonic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4773 | 55 |
| Alfa Chemistry | 1-516-6625404 | support@alfa-chemistry.com | United States | 9170 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shenzhen Regent Biochemical Technology Co., Ltd. | 0755-85201366 18938635012 | sales@regentsciences.com | China | 9383 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8137 | 58 |
View Latest Price from 5,6-Dehydroarachidonic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-22 | 5,6-dehydro Arachidonic Acid
58688-54-3
|
$673.00 | 10g | TargetMol Chemicals Inc. |
-
- 5,6-dehydro Arachidonic Acid
58688-54-3
- $673.00
- TargetMol Chemicals Inc.
