N-(2-Hydroxy-1r-methylethyl)-hexadecanamide
- CAS No.
- 142128-47-0
- Chemical Name:
- N-(2-Hydroxy-1r-methylethyl)-hexadecanamide
- Synonyms
- R-1 PMA;R-PALMITOYL-(1-METHYL) ETHANOLAMIDE;(R)-N-(1-Hydroxypropan-2-yl)palmitamide;N-[(2R)-1-hydroxypropan-2-yl]hexadecanamide;N-(2-Hydroxy-1r-methylethyl)-hexadecanamide;Hexadecanamide, N-[(1R)-2-hydroxy-1-methylethyl]-
- CBNumber:
- CB7679522
- Molecular Formula:
- C19H39NO2
- Molecular Weight:
- 313.52
- MDL Number:
- MFCD03412033
- MOL File:
- 142128-47-0.mol
- MSDS File:
- SDS
N-(2-Hydroxy-1r-methylethyl)-hexadecanamide price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 90353 | R-Palmitoyl-(1-methyl) Ethanolamide ≥98% | 142128-47-0 | 5mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 90353 | R-Palmitoyl-(1-methyl) Ethanolamide ≥98% | 142128-47-0 | 10mg | $68 | 2026-04-30 | Buy |
| Cayman Chemical | 90353 | R-Palmitoyl-(1-methyl) Ethanolamide ≥98% | 142128-47-0 | 50mg | $288 | 2026-04-30 | Buy |
| ChemScene | CS-0508450 | (R)-N-(1-Hydroxypropan-2-yl)palmitamide 98% | 142128-47-0 | 5mg | $114 | 2026-06-04 | Buy |
| ChemScene | CS-0508450 | (R)-N-(1-Hydroxypropan-2-yl)palmitamide 98% | 142128-47-0 | 10mg | $204 | 2026-06-04 | Buy |
N-(2-Hydroxy-1r-methylethyl)-hexadecanamide Chemical Properties, Uses, Production
Uses
(R)-N-(1-Hydroxypropan-2-yl)palmitamide (compound 24) is a substrate analog inhibitor of phospholipase A2[1].
Definition
ChEBI: R-Palmitoyl-(1-methyl) Ethanolamide is a fatty amide.
Biological Activity
r-palmitoyl-(1-methyl) ethanolamide, a synthetic analog of palmitoyl ethanolamide (pea), incorporates the (r)-methyl group vicinal to the alcohol on the ethanolamine moiety. the analogous modification to arachidonoyl ethanolamide (aea) protects the molecule from hydrolysis by fatty acid amide hydrolase, prolongs duration of action and enhances potency in vivo [1].pea is an endogenous cannabinoid existed in mammalian tissues, such as liver and brain. pea has also been isolated from egg yolk [2, 3]. pea is a compound with documented anti-nociceptive and anti-inflammatory effects. during inflammation, pea is accumulated and exihibits anti-inflammatory effects, including beneficial effects in clinically relevant animal models of inflammatory pain [4].
References
[1] abadji v, lin s, taha g, et al. (r)-methanandamide: a chiral novel anandamide possessing higher potency and metabolic stability[j]. journal of medicinal chemistry, 1994, 37(12): 1889-1893.
[2] bachur n r, masek k, melmon k l, et al. fatty acid amides of ethanol-amine in mammalian tissues[j]. journal of biological chemistry, 1965, 240: 1019-1024.
[3] ganley o h, graessle o e, robinson h j, et al. anti-inflammatory activity of compounds obtained from egg yolk, peanut oil, and soybean lecithin[j]. journal of laboratory and clinical medicine, 1958, 51: 709-714.
[4] lambert d m, vandevoorde s, jonsson k o, et al. the palmitoylethanolamide family: a new class of anti-inflammatory agents [j]. current medicinal chemistry, 2002, 9(6): 663-674.
N-(2-Hydroxy-1r-methylethyl)-hexadecanamide Preparation Products And Raw materials
N-(2-Hydroxy-1r-methylethyl)-hexadecanamide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Guangzhou Younan Technology Co., Ltd | 020-82000279 18988941452 | YN_research@163.com | China | 2984 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| SHANGHAI ZZBIO CO., LTD. | 18019219489 18901678489 | tech@zzbioco.com | China | 12062 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
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