2-Nitro-5-thiocyanatobenzoic acid
- CAS No.
- 30211-77-9
- Chemical Name:
- 2-Nitro-5-thiocyanatobenzoic acid
- Synonyms
- NTCB;Nitrothiocyanobenzoic acid;2-NITRO-5-THIOCYANOBENZOIC ACID;2-nitro-5-thiocyanato-benzoicaci;2-Nitro-5-thiocyanatobenzoic acid;2-Nitro-5-thiocyanatobenzoicAcid>Benzoic acid,2-nitro-5-thiocyanato-;2-Nitro-5-thiocyanatobenzoic acid,98%;2-Nitro-5-thiocyanobenzoic acid, NTCB;2-Nitro-5-thiocyanatobenzoic acid powder
- CBNumber:
- CB7706488
- Molecular Formula:
- C8H4N2O4S
- Molecular Weight:
- 224.19
- MDL Number:
- MFCD00007139
- MOL File:
- 30211-77-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 156-157 °C(lit.) |
|---|---|
| Boiling point | 449.0±40.0 °C(Predicted) |
| Density | 1.63 |
| refractive index | 1.5690 (estimate) |
| Flash point | 225.4℃ |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | DMF: 25 mg/ml; DMSO: 11 mg/ml; Ethanol: 25 mg/ml; PBS (pH 7.2): 0.3 mg/ml |
| pka | 1.75±0.25(Predicted) |
| form | powder |
| color | yellow |
| BRN | 2124001 |
| InChI | InChI=1S/C8H4N2O4S/c9-4-15-5-1-2-7(10(13)14)6(3-5)8(11)12/h1-3H,(H,11,12) |
| InChIKey | NQUNIMFHIWQQGJ-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC(SC#N)=CC=C1[N+]([O-])=O |
| FDA UNII | O5VCA1GS5O |
| EPA Substance Registry System | Benzoic acid, 2-nitro-5-thiocyanato- (30211-77-9) |
| UNSPSC Code | 12352209 |
| NACRES | NA.26 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 8-21 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29309090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
2-Nitro-5-thiocyanatobenzoic acid price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | N7009 | 2-Nitro-5-thiocyanatobenzoic acid powder | 30211-77-9 | 250mg | $116 | 2026-04-30 | Buy |
| Sigma-Aldrich | N7009 | 2-Nitro-5-thiocyanatobenzoic acid powder | 30211-77-9 | 1g | $307 | 2026-04-30 | Buy |
| TCI Chemical | N0516 | 2-Nitro-5-thiocyanatobenzoic Acid >97.0%(HPLC)(T) | 30211-77-9 | 1g | $127 | 2026-04-30 | Buy |
| Cayman Chemical | 18236 | 2-Nitro-5-thiocyanatobenzoic Acid ≥98% | 30211-77-9 | 250mg | $63 | 2026-04-30 | Buy |
| Cayman Chemical | 18236 | 2-Nitro-5-thiocyanatobenzoic Acid ≥98% | 30211-77-9 | 1g | $134 | 2026-04-30 | Buy |
2-Nitro-5-thiocyanatobenzoic acid Chemical Properties, Uses, Production
Chemical Properties
yellow fine crystalline powder
Uses
2-Nitro-5-thiocyanatobenzoic acid (NTCB) is a highly reactive reagent that transfers its cyano group rapidly to a nucleophilic thiolate. 2-Nitro-5-thiocyanatobenzoic acid has been proposed as a reagent for converting thiol groups in proteins into their S-cyano derivatives[1][2].
Biological Activity
2-nitro-5-thiocyanatobenzoic acid (NTCB) is commonly used to cyanylate and cleave proteins at cysteine residues.
References
[1] Qiao Y, et al. Site-Specific Conversion of Cysteine in a Protein to Dehydroalanine Using 2-Nitro-5-thiocyanatobenzoic Acid. Molecules. 2021;26(9):2619. Published 2021 Apr 29. DOI:10.3390/molecules26092619
[2] Price NC. Alternative products in the reaction of 2-nitro-5-thiocyanatobenzoic acid with thiol groups. Biochem J. 1976;159(1):177-180. DOI:10.1042/bj1590177
2-Nitro-5-thiocyanatobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
2-Nitro-5-thiocyanatobenzoic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8137 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Suzhou Highfine Biotech Co., Ltd | 0512-69209928 18796809688 | zhouyingxiang@highfine.com | China | 472 | 75 |
| Nanjing Habo Medical Technology Co., Ltd. | 13376080562 13376090521 | sales@habotech.com | China | 724 | 60 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Maya High Purity Chemicals | +86 (573) 82222445 (0)18006601000 452520369 | sales@maya-r.com | China | 11693 | 57 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
| TCI Europe | 320-37350700 | sales@tcieurope.eu | Europe | 23654 | 75 |
| TCI AMERICA | 800-4238616 | sales@tciamerica.com | Americas | 23636 | 75 |
View Latest Price from 2-Nitro-5-thiocyanatobenzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-07-18 | 2-NITRO-5-THIOCYANATOBENZOIC ACID
30211-77-9
|
$1.00 | 1KG | 99% | 20T | Shaanxi Dideu Medichem Co. Ltd | |
 |
2019-12-29 | 4,4'-Dinitrostilbene-2,2'-disulfonic acid
30211-77-9
|
$1.00 | 1g | 99% | 10000KGS | Career Henan Chemical Co |
-
- 2-NITRO-5-THIOCYANATOBENZOIC ACID
30211-77-9
- $1.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- 4,4'-Dinitrostilbene-2,2'-disulfonic acid
30211-77-9
- $1.00
- 99%
- Career Henan Chemical Co
30211-77-9 (2-Nitro-5-thiocyanatobenzoic acid) Related Search:
1of4
