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Methylaminoacetonitrile hydrochloride

Methylaminoacetonitrile hydrochloride structure

CAS No.: 25808-30-4

Chemical Name:: Methylaminoacetonitrile hydrochloride

Synonyms: SARCOSINITRILE;JACS-25808-30-4;Methylaminoacetonitr;METHYLAMINOACETONITRILE HCL;SARCOSINITRILE HYDROCHLORIDE;N-METHYL AMINOACETONITRILE HCL;SARCOSINE NITRILE HYDROCHLORIDE;cyanomethyl(methyl)ammonium chloride;(methylamino)acetonitrilhydrochlorid;METHYLAMINOACETONITRILE HYDROCHLORIDE

CBNumber:: CB7722259

Molecular Formula:: C3H7ClN2

Molecular Weight:: 106.55

MDL Number:: MFCD00012587

MOL File:: 25808-30-4.mol

MSDS File:: SDS

Last updated:2026-05-28 02:58:48

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Methylaminoacetonitrile hydrochloride Properties

Melting point	103-106 °C(lit.)
storage temp.	Inert atmosphere,Room Temperature
Appearance	White to off-white Solid
BRN	3908975
InChI	1S/C3H6N2.ClH/c1-5-3-2-4;/h5H,3H2,1H3;1H
InChIKey	DFKBQHBEROHUNF-UHFFFAOYSA-N
SMILES	Cl.CNCC#N
CAS DataBase Reference	25808-30-4(CAS DataBase Reference)
FDA UNII	R6AU3C4NY5
EPA Substance Registry System	Acetonitrile, (methylamino)-, monohydrochloride (25808-30-4)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

TSCA

TSCA listed

HS Code

29269090

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	1
2		0

Methylaminoacetonitrile hydrochloride price More Price(43)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	M28103	Methylaminoacetonitrile hydrochloride 98%	25808-30-4	25g	$137	2022-05-15	Buy
Sigma-Aldrich	M28103	Methylaminoacetonitrile hydrochloride 98%	25808-30-4	100g	$409	2022-05-15	Buy
Apolloscientific	OR322050	Methylaminoacetonitrile hydrochloride >98%	25808-30-4	25g	$21	2026-06-04	Buy
Apolloscientific	OR322050	Methylaminoacetonitrile hydrochloride >98%	25808-30-4	100g	$30	2026-06-04	Buy
Apolloscientific	OR322050	Methylaminoacetonitrile hydrochloride >98%	25808-30-4	500g	$124	2026-06-04	Buy

Product number	Packaging	Price	Buy
M28103	25g	$137	Buy
M28103	100g	$409	Buy
OR322050	25g	$21	Buy
OR322050	100g	$30	Buy
OR322050	500g	$124	Buy

Methylaminoacetonitrile hydrochloride Chemical Properties, Uses, Production

Chemical Properties

Yellow crystal

Uses

Methylaminoacetonitrile hydrochloride can be used as an intermediate in pharmaceutical and chemical synthesis. It is the raw material for the preparation of tadalafil. Approved by the FDA in 2003, tadalafil was marketed in the United States as a drug for the treatment of erectile dysfunction in men.

Synthesis

A method of preparing methylaminoacetonitrile hydrochloride, comprising: (1) reacting methylamine hydrochloride, sodium cyanide and formaldehyde as reaction raw materials to form methylaminoacetonitrile in the presence of a catalyst; and (2) reacting said methylaminoacetonitrile with hydrochloric acid to form said methylaminoacetonitrile hydrochloride, and in step (1) the reaction is carried out at below 0 C. using 3-mercaptopropionic acid as a catalyst, and the amount of catalyst is from 0.9 to 1.1 times.

Methylaminoacetonitrile hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

N-Boc-N-methylethylenediamine 3,5-DibroMo-1-Methylpyrazin-2(1H)-one 2-(N-Boc-methylamino)acetonitrile

Methylaminoacetonitrile hydrochloride Suppliers

Global Suppliers ( 197)

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
INTATRADE GmbH	+49 3493/605464	sales@intatrade.de	Germany	3563	66
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
Beijing Ouhe Technology Co., Ltd	13552068683 13522913783	2355560935@qq.com	China	11777	60
Accela ChemBio Co.,Ltd.	021-50795510 4000665055	marketing@accelachem.com	China	10972	64
Shanghai Longsheng chemical Co.,Ltd.	58099637 13585536065	sales@shlschem.com	China	9880	59
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
XiaoGan ShenYuan ChemPharm co,ltd	15527621225; 15527621225	1791901229@qq.com	China	6741	52
Shandong Xiya Chemical Co., Ltd	13355009207 13355009207	3007715519@qq.com	China	18722	57
Syntechem Co.,Ltd		info@syntechem.com	China	12973	57

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
INTATRADE GmbH	66
Alfa Aesar	84
Beijing Ouhe Technology Co., Ltd	60
Accela ChemBio Co.,Ltd.	64
Shanghai Longsheng chemical Co.,Ltd.	59
Shanghai Hanhong Scientific Co.,Ltd.	64
XiaoGan ShenYuan ChemPharm co,ltd	52
Shandong Xiya Chemical Co., Ltd	57
Syntechem Co.,Ltd	57

View Latest Price from Methylaminoacetonitrile hydrochloride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-20	Methylaminoacetonitrile hydrochloride 25808-30-4	$1.10	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
2026-06-30	Methylaminoacetonitrile hydrochloride 25808-30-4		1KG	98.0%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2021-07-13	2-(methylamino)acetonitrile,hydrochloride 25808-30-4	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd

Methylaminoacetonitrile hydrochloride
25808-30-4
$1.10
99.00%
Dideu Industries Group Limited

Methylaminoacetonitrile hydrochloride
25808-30-4
98.0%
Shaanxi Dideu New Materials Co. Ltd

2-(methylamino)acetonitrile,hydrochloride
25808-30-4
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

Methylaminoacetonitrile hydrochloride Spectrum

Methylaminoacetonitrile hydrochloride(25808-30-4)¹HNMR Methylaminoacetonitrile hydrochloride(25808-30-4)FT-IR Methylaminoacetonitrile hydrochloride(25808-30-4)IR Methylaminoacetonitrile hydrochloride(25808-30-4)Raman

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MethylaMinoacetonitrile Hydrochloride, 97+% N-METHYL AMINOACETONITRILE HCL N-Methylaminoacetonitrile hydrochloride 2-Methylaminoacetonitrile hydrochloride Methylaminoacetonitrile Hydrochliride 2-(methylamino)ethanenitrile hydrochloride (methylamino)-acetonitrilmonohydrochloride SARCOSINE NITRILE HYDROCHLORIDE SARCOSINITRILE SARCOSINITRILE HYDROCHLORIDE ACETONITRILE, (METHYLAMINO)-, MONOHYDROCHLORIDE METHYLAMINOACETONITRILE HCL METHYLAMINOACETONITRILE HYDROCHLORIDE cyanomethyl(methyl)ammonium chloride METHYLAMINOACETONITRILE HYDROCHLORIDE, 9 8% N-(methylamino)acetonitrilium hydrochloride Methylaminoacetonitr AMinoMethylacetonitrile hydrochloride Acetonitrile,2-(methylamino)-, hydrochloride JACS-25808-30-4 Methylaminoacetonitrile hydrochloride ISO 9001：2015 REACH (methylamino)acetonitrilhydrochlorid Methylaminoacetonitrile hydrochloride,25808-30-4 Methylaminoacetonitrile hydrochloride 98% 25808-30-4 CH3NHCH2CNHCl C3H6N2HCl C3H7ClN2 Cyanides/Nitriles Organic Building Blocks Nitrogen Compounds Building Blocks C1 to C5 Building Blocks C1 to C5 Chemical Synthesis Cyanides/Nitriles Nitrogen Compounds Organic Building Blocks Anthraquinones, Hydroquinones and Quinones