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N-Boc-N-methylethylenediamine

N-Boc-N-methylethylenediamine structure

CAS No.: 121492-06-6

Chemical Name:: N-Boc-N-methylethylenediamine

Synonyms: N-Boc-(2-Aminoethyl)-N-methylamine;tert-butyl 2-aminoethyl(methyl)carbamate;BOC,ME-EDA;CAS:121492-06-6;BUTTPARK 90\06-19;BOC-N-METHYLETHYLENEDIAMINE;N-(2-AMinoethyl)-N-Methylca;N-BOC-N-METHYLETHYLENEDIAMINE;1-BOC-1-METHYL-ETHYLENEDIAMINE;N-Boc-N-methyl-1,2-diaminoethane

CBNumber:: CB3424935

Molecular Formula:: C8H18N2O2

Molecular Weight:: 174.24

MDL Number:: MFCD01317789

MOL File:: 121492-06-6.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 06:31:39

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N-Boc-N-methylethylenediamine Properties

Melting point	248-251 °C (decomp)
Boiling point	79°C/0.4mmHg(lit.)
Density	0.975 g/mL at 20 °C (lit.)
refractive index	n20/D 1.447
Flash point	>100 °C
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
solubility	Chloroform (Slightly), Methanol (Slightly)
pka	9.44±0.10(Predicted)
form	Liquid
color	Clear colorless to pale yellow
BRN	3588326
InChI	InChI=1S/C8H18N2O2/c1-8(2,3)12-7(11)10(4)6-5-9/h5-6,9H2,1-4H3
InChIKey	QYJVBVKFXDHFPQ-UHFFFAOYSA-N
SMILES	C(OC(C)(C)C)(=O)N(CCN)C
CAS DataBase Reference	121492-06-6(CAS DataBase Reference)
UNSPSC Code	12352200
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05

Signal word

Danger

Hazard statements

H314

Precautionary statements

P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405

PPE

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Hazard Codes

Risk Statements

Safety Statements

26-36/37/39-45

RIDADR

2734

WGK Germany

HazardClass

PackingGroup

Ⅲ

HS Code

2924190090

Storage Class

8A - Combustible corrosive hazardous materials

Hazard Classifications

Skin Corr. 1B

Limited Quantities

5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

NFPA 704

	1
3		1

N-Boc-N-methylethylenediamine price More Price(94)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	15567	N-Boc-N-methylethylenediamine ≥97.0% (GC)	121492-06-6	1ml	$130	2023-06-20	Buy
Sigma-Aldrich	15567	N-Boc-N-methylethylenediamine ≥97.0% (GC)	121492-06-6	5ml	$181	2022-05-15	Buy
TCI Chemical	B4277	N-(tert-Butoxycarbonyl)-N-methyl-1,2-ethylenediamine >95.0%(GC)(T)	121492-06-6	1mL	$38	2026-04-30	Buy
TCI Chemical	B4277	N-(tert-Butoxycarbonyl)-N-methyl-1,2-ethylenediamine >95.0%(GC)(T)	121492-06-6	5mL	$114	2026-04-30	Buy
Usbiological	265320	Boc-N-methylethylenediamine	121492-06-6	1g	$350	2026-06-03	Buy

Product number	Packaging	Price	Buy
15567	1ml	$130	Buy
15567	5ml	$181	Buy
B4277	1mL	$38	Buy
B4277	5mL	$114	Buy
265320	1g	$350	Buy

N-Boc-N-methylethylenediamine Chemical Properties,Uses,Production

Uses

N-Boc-N-methylethylenediamine is a compound useful in organic synthesis and other chemical processes.

Chemical Properties

Liquid

Uses

Mono-protected building block.

reaction suitability

reagent type: cross-linking reagent

Synthesis

24424-99-5

109-81-9

121492-06-6

Step 1: N-methylethylenediamine (11.8 mL, 134.9 mmol) was dissolved in acetonitrile (300 mL) and cooled to -30 °C. Subsequently, triethylamine (TEA, 7.46 mL, 53.9 mmol) was added to this solution, followed by dropwise addition of di-tert-butyl dicarbonate (Boc2O, 9.81 g, 45 mmol) in acetonitrile solution. The reaction mixture was stirred at room temperature for 2 hours. After completion of the reaction, the insoluble material was removed by Celite filtration. The filtrate was purified by silica gel column chromatography (elution gradient: 1:50→1:20→1:10 ethyl acetate/hexane) to afford tert-butyl N-(2-aminoethyl)-N-methylcarbamate (CXVIII) as a yellow oil (5.2 g, 29.9 mmol, 66% yield). The product was confirmed by electrospray ionization mass spectrometry (ESIMS) with molecular formula C8H18N2O2, m/z 175 (M + H).

References

[1] Patent: US2008/318957, 2008, A1. Location in patent: Page/Page column 72; 73
[2] Journal of Medicinal Chemistry, 2000, vol. 43, # 16, p. 3093 - 3102

N-Boc-N-methylethylenediamine synthesis

Synthesis of N-Boc-N-methylethylenediamine from 2-(2-N-BOC-N-METHYL-AMINOETHYL)-1H-ISOINDOLE-1,3(2H)-DIONE

N-Boc-N-methylethylenediamine Preparation Products And Raw materials

Raw materials

2-(2-N-BOC-N-METHYL-AMINOETHYL)-1H-ISOINDOLE-1,3(2H)-DIONE tert-Butyl Methyl(2-(2,2,2-trifluoroacetaMido)ethyl)carbaMate tert-Butyl N-(2-bromoethyl)carbamate BOC-SAR-OH N-Boc-2-azidoethylaMine

tert-Butyl (2-azidoethyl)(methyl)carbamate 2-(N-BOC-METHYLAMINO)ACETONITRILE N-carbamoylmethyl-N-methyl-carbamic acid t-butyl ester Methylaminoacetonitrile hydrochloride (2-HYDROXYETHYL)METHYLCARBAMIC ACID 1,1-DIMETHYLETHYL ESTER

tert-Butyl 2-(methylamino)ethylcarbamate Di-tert-butyl dicarbonate N-METHYLETHYLENEDIAMINE

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Preparation Products

N-Boc-N-methylethylenediamine Suppliers

Global( 250)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Chiral Chemicals Inc.	021-37285021 13472570865	tym7xi@aliyun.com	China	299	64
Shanghai ZaiQi Bio-Tech Co., Ltd.	+86-021-54824098 15317552526	sales@chemzq.com	China	254	55
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Suzhou Highfine Biotech Co., Ltd	0512-69209928 18796809688	zhouyingxiang@highfine.com	China	472	75
Wuhan Chemwish Technology Co., Ltd	86-027-67849912	sales@chemwish.com	China	35884	56
Beijing Ouhe Technology Co., Ltd	13552068683 13522913783	2355560935@qq.com	China	11777	60

Supplier	Advantage
Shanghai Chiral Chemicals Inc.	64
Shanghai ZaiQi Bio-Tech Co., Ltd.	55
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Alfa Aesar	84
TCI (Shanghai) Development Co., Ltd.	81
Energy Chemical	61
Suzhou Highfine Biotech Co., Ltd	75
Wuhan Chemwish Technology Co., Ltd	56
Beijing Ouhe Technology Co., Ltd	60

View Lastest Price from N-Boc-N-methylethylenediamine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-03-20	N-Boc-N-methylethylenediamine 121492-06-6		1KG	99%	20 mt	Hebei Chuanghai Biotechnology Co., Ltd
	2019-07-06	N-Boc-N-methylethylenediamine 121492-06-6	$1.00	1KG	99%	1000KG	Career Henan Chemical Co

N-Boc-N-methylethylenediamine
121492-06-6
99%
Hebei Chuanghai Biotechnology Co., Ltd

N-Boc-N-methylethylenediamine
121492-06-6
$1.00
99%
Career Henan Chemical Co

121492-06-6(N-Boc-N-methylethylenediamine)Related Search:

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N-METHYLETHYLENEDIAMINE Diisobutyl phthalate Diethylene glycol monobutyl ether Urethane tert-Butyl peroxybenzoate

Methyl anthranilate N,N-Dimethylethylenediamine 4-Aminobenzoic acid tert-Butyl acetate tert-Butyl carbazate

Butyl acrylate Thiophanate-methyl tert-Butanol

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TERT-BUTYL N-(2-AMINOETHYL)-N-METHYLCARBAMATE N-T-BUTYLOXYCARBONYL-N-METHYL-ETHYLENEDIAMINE N-TERT-BUTYLOXYCARBONYL-N-METHYL-ETHYLENEDIAMINE N-BOC-N-METHYLETHYLENEDIAMINE N-(2-AMINOETHYL)-N-METHYL CARBAMIC ACID TERT-BUTYL ESTER N-(2-AMINOETHYL)-N-BOC-METHYLAMINE BOC,ME-EDA BOC-N-METHYLETHYLENEDIAMINE BUTTPARK 90\06-19 (2-AMINO-ETHYL)-METHYL-CARBAMIC ACID TERT-BUTYL ESTER 1-BOC-1-METHYL-ETHYLENEDIAMINE N-(2-Aminoethyl)-N-methyl carbamic acid tert-butyl N-Boc-(2-Aminoethyl)-N-methylamine Carbamic acid, N-(2-aminoethyl)-N-methyl-, 1,1-dimethylethyl ester N-Boc-N-methylethylenediamine ,98% tert-butyl 2-aminoethyl(methyl)carbamate tert-butyl (2-aminoethyl)methylcarbamate(SALTDATA: FREE) 2-(N-Boc-N-methylamino)ethylamine 1-BOC-1-methyl-ethylenediamine-HCl 2-Methylpropan-2-yl N-(2-AMinoethyl)-N-MethylcarbaMate N-(2-AMinoethyl)-N-Methylca N-(2-AMinoethyl)-N-Methyl-carbaMic Acid 1,1-DiMethylethyl Ester N-(2-AMinoethyl)-N-Methyl-N-(tert-butoxycarbonyl)aMine N-(tert-Butoxycarbonyl)-N-methylethane-1,2-diamine, tert-Butyl (2-aminoethyl)methylcarbamate N-Methylethane-1,2-diamine, N-BOC protected N-(tert-Butoxycarbonyl)-N-methyl-1,2-ethylenediamine N1-BOC-N1-METHYL-1,2-ETHYLENEDIAMINE Boc-N-methylethylenediamine≥ 98% (GC) N-(tert-Butoxycarbonyl)-N-methyl-1,2-ethylenediamine > N-(tert-Butoxycarbonyl)-N-methyl-1,2-diaminoethane N-Boc-N-methyl-1,2-diaminoethane N-Boc-N-methyl-1,2-ethylenediamine N-Boc-N-methylethylenediamine USP/EP/BP N-Boc-N-methylethylenediamine 121492-06-6 2-Methyl-2-propanyl (2-aminoethyl)methylcarbamate CAS:121492-06-6 N-Boc-N-methylethylenediamine 121492-06-6 Building Blocks Nitrogen Compounds Organic Building Blocks Protected Amines Bifunctional Linkers Building Blocks Chemical Biology Chemical Synthesis Linkers and Crosslinkers Nitrogen Compounds Organic Building Blocks Protected Amines Small molecule