CAPSO
- CAS No.
- 73463-39-5
- Chemical Name:
- CAPSO
- Synonyms
- CAPSO;CAPSO ULTRAPURE;CAPSO anhydrous;CAPSO Free Acid;CAPSO Buffer salt;CAPSO, Biological Buffer;CAPSO FREE ACID SIGMAULTRA;CAPSO,97+%,for biochemistry;CAPSO Buffer extrapure, 99%;CAPSO, MOLECULAR BIOLOGY GRADE
- CBNumber:
- CB7728266
- Molecular Formula:
- C9H19NO4S
- Molecular Weight:
- 237.32
- MDL Number:
- MFCD00041778
- MOL File:
- 73463-39-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 270-274°C |
|---|---|
| Density | 1.29±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | H2O: 0.1 g/mL, clear, colorless |
| form | Powder |
| color | White |
| pka | 9.6(at 25℃) |
| Odor | Odorless |
| PH | 2.5-4.0 |
| PH Range | 8.9 - 10.3 |
| Water Solubility | Soluble in water (10 g+ 90 ml). |
| BRN | 5939234 |
| InChI | InChI=1S/C9H19NO4S/c11-9(7-15(12,13)14)6-10-8-4-2-1-3-5-8/h8-11H,1-7H2,(H,12,13,14) |
| InChIKey | INEWUCPYEUEQTN-UHFFFAOYSA-N |
| SMILES | C(S(O)(=O)=O)C(O)CNC1CCCCC1 |
| CAS DataBase Reference | 73463-39-5(CAS DataBase Reference) |
| UNSPSC Code | 12161700 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P280-P261-P271 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 20/21/22-36/37/38 | |||||||||
| Safety Statements | 22-24/25-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29221980 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
CAPSO price More Price(51)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C2278 | CAPSO ≥99% anhydrous basis (titration) | 73463-39-5 | 25g | $63.2 | 2026-04-30 | Buy |
| Sigma-Aldrich | C2278 | CAPSO ≥99% anhydrous basis (titration) | 73463-39-5 | 1kg | $1040 | 2026-04-30 | Buy |
| TCI Chemical | C2426 | 3-(Cyclohexylamino)-2-hydroxypropane-1-sulfonic Acid | 73463-39-5 | 25G | $27 | 2026-04-30 | Buy |
| TCI Chemical | C2426 | 3-(Cyclohexylamino)-2-hydroxypropane-1-sulfonic Acid | 73463-39-5 | 100G | $77 | 2026-04-30 | Buy |
| Biosynth | FC15823 | CAPSO | 73463-39-5 | 0.25kg | $150 | 2026-06-04 | Buy |
CAPSO Chemical Properties, Uses, Production
Description
CAPSO is a useful secondary standard buffer. The second dissociation constant pK2 value of CAPSO has been measured and the useful pH range for CAPSO is 8.9 - 10.3. It is a biological and zwitterionic buffer commonly categorized as a Good's buffer. CAPSO has many applications some of which include immunoblotting and westerns. Additionally, CAPSO is used in the electrotransfer of proteins to PVDF or nitrocellulose membranes. CAPSO buffer has very low metal-binding constants and is, therefore, particularly suited to investigate metal-dependent enzymes. CAPSO is a very water-soluble buffering reagent with an optimum buffering pH of 10.4 and minimal reactivity with enzymes or proteins with minimal salt effects.
Chemical Properties
white powder
Uses
CAPSO was used as biological buffer in the following studies:
To maintain pH 9 during water leach test for the analysis of high-carbon coal fly ash-soil mixtures.
Chemiluminescent in situ hybridization using soybean peroxidase-labeled peptide nucleic acid (PNA) probes.
Preparation of planar bilayer lipid membranes.
It may be employed as buffer for the electrophoretic analyses in non-denaturing gels, to investigate macromolecular self-association of ADP-ribosyltransferase protein in solution.
Uses
CAPSO is used in various biological applications such as electrophoresis. Specific applications include buffers for protein separations and diagnostic reagent production. Also used as biological buffer in the following studies, to maintain pH 9 during water leach test for the analysis of high-carbon coal fly ash-soil mixtures, chemiluminescent in situ hybridization using soybean peroxidase-labeled peptide nucleic acid (PNA) probes, preparation of planar bilayer lipid membranes.
Definition
ChEBI: 3-(cyclohexylamino)-2-hydroxy-1-propanesulfonic acid is an amine.
Preparation
Add sodium sulfite (25.20 g, 0.2 mol) and sodium bisulfite (64.48 g, 0.62 mol) to the three-mouth flask. Heat to dissolve the reactants in water and slowly add epichlorohydrin (50.08 g, 0.54 mol) to the bottle. After vigorous stirring at 30 °C for 2 h, the mixture is cooled in an ice bath. CAPSO is obtained by vacuum suction, drying, and recrystallization.
General Description
CAPSO is a useful secondary standard buffer. Second dissociation constant pK2 value of CAPSO has been measured. Useful pH range for CAPSO is 8.9 - 10.3.
CAPSO Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hunan Hengfei bio-pharmaceutical Co. , Ltd. | 0746-6222194 13874779848 | 57182844@qq.com | China | 52 | 58 |
| Suzhou yacoo science co.,Ltd | 0512-87182055 13451648594 | sales@yacoo.com.cn | China | 4576 | 58 |
| Suzhou Genemill Biotechnology Co.,Ltd | 0512-65917170 | xiely@genemill.com | China | 36 | 58 |
| Hunan Hui Bai Yi New Materials Co., Ltd | 0745-2866551 19976851779 | 3643281807@qq.com | China | 3395 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Nanjing Search Biotech Co., Ltd | +86-025-81682922 +86-13515111588 | sales@searchbio.com.cn | China | 137 | 68 |
View Latest Price from CAPSO manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-17 | CAPSO
73463-39-5
|
1KG | 99%min | 500kgs | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-04-21 | 3-(Cyclohexylamino)2-hydroxy-1-propanesulfonic acid （CAPSO）
73463-39-5
|
25kg | ≥99 % | 300tons/year | Wuhan Hugarise New Material Co.,Ltd | ||
 |
2026-03-20 | 3-(Cyclohexylamino)-2-hydroxy-1-propanesulfonic acid
73463-39-5
|
$1.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- CAPSO
73463-39-5
- $0.00
- 99%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 3-(Cyclohexylamino)2-hydroxy-1-propanesulfonic acid （CAPSO）
73463-39-5
- $0.00
- ≥99 %
- Wuhan Hugarise New Material Co.,Ltd
-
- 3-(Cyclohexylamino)-2-hydroxy-1-propanesulfonic acid
73463-39-5
- $1.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
