8-Chloroadenine
- CAS No.
- 28128-28-1
- Chemical Name:
- 8-Chloroadenine
- Synonyms
- 8-CL-ADE;8-Chloroadenine;8-Chloro-7H-purin-6-aMine;8-chloro-9H-purin-6-aMine;9H-Purin-6-amine, 8-chloro-
- CBNumber:
- CB7757273
- Molecular Formula:
- C5H4ClN5
- Molecular Weight:
- 169.57
- MDL Number:
- MFCD22067305
- MOL File:
- 28128-28-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
8-Chloroadenine price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 267505 | 8-Chloroadenine | 28128-28-1 | 1mg | $686 | 2026-06-03 | Buy |
| Usbiological | 267505 | 8-Chloroadenine | 28128-28-1 | 5mg | $1431 | 2026-06-03 | Buy |
| Usbiological | 267505 | 8-Chloroadenine | 28128-28-1 | 10mg | $2114 | 2026-06-03 | Buy |
| Biosynth | FC09245 | 8-Chloroadenine | 28128-28-1 | 1mg | $285.71 | 2026-06-04 | Buy |
| Biosynth | FC09245 | 8-Chloroadenine | 28128-28-1 | 2mg | $476.38 | 2026-06-04 | Buy |
8-Chloroadenine Chemical Properties, Uses, Production
Synthesis
58-61-7
28128-28-1
Example 1 Synthesis of 8-chloroadenine (1) To a solution of DMA/HCl (0.5 M, 45 mL) of adenosine (2.67 g, 10 mmol) was added m-chloroperoxybenzoic acid (MCPBA, 3.22 g, 16 mmol, 87%) at room temperature and the reaction was carried out for 2.5 hours. Subsequently, MCPBA (0.9 g, 5 mmol) was added additionally and stirring was continued for 1 hour. Upon completion of the reaction, toluene (50 mL) was added and evaporated to dryness at 60 °C under vacuum. The residue was dissolved in water (50 mL) and extracted with ether (3 x 50 mL). The aqueous phase was adjusted to pH 5 with 2N NaOH and diluted with EtOH (100 mL). The solution was placed in a refrigerator overnight. The precipitated yellowish solid was collected by filtration, washed with cold EtOH (2 x 25 mL) and dried to give a product of 1.44 g (85.2% yield). The product was characterized as follows: melting point 305-310 °C (decomposition); IR (KBr) showed 630 cm1 (C-Cl) and 3100-3300 cm1 (NH) absorption peaks; UV spectra at pH 1 with λmax=262 nm (ε=8700), pH 7 with λmax=268 nm (ε=7900), and pH 11 with λmax= 269 nm (ε=8300); 1H NMR (MeSO-d) chemical shift δ 7.48 (broad peak, 2H, NH), 8.10 (single peak, 1H, C-H), 13.60 (broad peak, 1H, N-H).
References
[1] Patent: US4861873, 1989, A
8-Chloroadenine Preparation Products And Raw materials
Raw materials
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Preparation Products
8-Chloroadenine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66028182 17714375163 | yftan@aikonchem.com | China | 16674 | 50 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Amel Pharmatech Corporation | 027-888-4366503 13986279625 | sales@amelpharmatech.com | China | 4826 | 58 |
| TopScience Biochemical | 00852-68527855 | info@itopbiochem.com | China Hong Kong | 900 | 58 |
| Shanghai Sunway Pharmaceutical Technology Co.,Ltd. | 13611835272 13611835272 | mmwang@sunwaypharm.com | China | 44090 | 58 |
| Wuhan Jingkangen Biomedical Technology Co., Ltd | 13720134139 086-15871494362 13720134139 | orders@jknbiochem.com | China | 7283 | 58 |
| https://hanhongsci.com/ | 021-54306202 18917919676 | info@hanhongsci.com | China | 29982 | 58 |
| Wuhan Acumen Bio-Technology Co.,ltd | 027-027-16602739303 16602739303 | 673003916@qq.com | China | 4593 | 58 |
| Changsha Fuzhen Biotechnology Co.，LTD | 15111215862 18229892877 | 3062105966@qq.com | China | 5568 | 58 |
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