6-Mercaptohexan-1-ol
- CAS No.
- 1633-78-9
- Chemical Name:
- 6-Mercaptohexan-1-ol
- Synonyms
- 6-MERCAPTO-1-HEXANOL;6-MCH;6-Mercatohexan-1-ol;6-MERCAPTOHEXAN-1-OL;1-Hexanol, 6-mercapto-;6-mercaptoyl-1-hexylol;6-Mercapto-1-hexanol>6-Hydroxy-1-hexanethiol;6-Mercapto-1-hexanol 97%;6-Mercapto-1-hexanol ,97%
- CBNumber:
- CB7778009
- Molecular Formula:
- C6H14OS
- Molecular Weight:
- 134.24
- MDL Number:
- MFCD00068552
- MOL File:
- 1633-78-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 6-Mercapto-1-hexanol 97% | 451088 | 5ml | $95.1 |
| 6-Mercapto-1-hexanol 97% | 451088 | 25ml | $317 |
| 6-Mercapto-1-hexanol >98.0%(GC) | M2266 | 5g | $96 |
| 6-Mercapto-1-hexanol >98.0%(GC) | M2266 | 25g | $380 |
| 6-Mercapto-1-hexanol Asreported | 283299 | 25g | $319 |
| More product size | |||
| Boiling point | 225 °C(lit.) |
|---|---|
| Density | 0.981 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Sparingly), Methanol (Slightly) |
| form | liquid |
| pka | 10.47±0.10(Predicted) |
| color | Colourless |
| BRN | 1846871 |
| Stability | Air Sensitive |
| InChI | InChI=1S/C6H14OS/c7-5-3-1-2-4-6-8/h7-8H,1-6H2 |
| InChIKey | UGZAJZLUKVKCBM-UHFFFAOYSA-N |
| SMILES | C(O)CCCCCS |
| LogP | 1.370 (est) |
| EPA Substance Registry System | 1-Hexanol, 6-mercapto- (1633-78-9) |
| UNSPSC Code | 12352300 |
| NACRES | NA.23 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| RIDADR | UN 3334 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-13-23 | |||||||||
| HS Code | 29309090 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
6-Mercaptohexan-1-ol price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 451088 | 6-Mercapto-1-hexanol 97% | 1633-78-9 | 5ml | $95.1 | 2026-04-30 | Buy |
| Sigma-Aldrich | 451088 | 6-Mercapto-1-hexanol 97% | 1633-78-9 | 25ml | $317 | 2026-04-30 | Buy |
| TCI Chemical | M2266 | 6-Mercapto-1-hexanol >98.0%(GC) | 1633-78-9 | 5g | $96 | 2026-04-30 | Buy |
| TCI Chemical | M2266 | 6-Mercapto-1-hexanol >98.0%(GC) | 1633-78-9 | 25g | $380 | 2026-04-30 | Buy |
| Usbiological | 283299 | 6-Mercapto-1-hexanol Asreported | 1633-78-9 | 25g | $319 | 2026-06-03 | Buy |
6-Mercaptohexan-1-ol Chemical Properties,Uses,Production
Chemical Properties
Colorless to light yellow liquid
Uses
6-Mercapto-1-hexanolcan be used as a chemical linker for anchoring biological molecules to gold surfaces.
Uses
This compound is used to produce hydrophilic SAMs. The resulting monolayers which are terminated with alcohols can be further functionalized with various groups even when attached to gold nanoclusters.
Uses
MCH is coated on a piezoelectric crystal which can be used for the fabrication of chemical sensor to differentiate between cheese varieties. Self assembled monolayers of MCH can be used on gold surfaces for bio-sensing applications. It can also be used as a monolayer for the surface modification of gold-polyaniline (Au-PANI) nanocomposites for the development of aptamer based biosensors (aptasensors).
General Description
6-mecapto-1-hexanol (MCH) forms a self-assembled monolayer (SAM) with identically represented C6 spacer. MCH is a tool for surface coating that enables blocking of active sites and non-specific absorption.
reaction suitability
reagent type: linker
Synthesis
4286-55-9
1633-78-9
The general procedure for the synthesis of 6-mercaptohexan-1-ol from 6-bromohexanol was as follows: 6-bromohexanol (1 g, 5.60 mmol) was mixed with thiourea (0.64 g, 8.40 mmol) and NaOH (0.1 M) in 1,4-dioxane (4 mL), and the reaction was carried out at reflux for 4 hours. After completion of the reaction, the reaction mixture was cooled and the solvent was removed under vacuum. Subsequently, the pH of the reaction mixture was adjusted to 4 by addition of dilute hydrochloric acid. hydrochloric acid and thiol derivatives in the reaction mixture were extracted with dichloromethane. The organic layer was dried with anhydrous sodium sulfate and then concentrated to give 6-mercaptohexan-1-ol as a yellow oil. Yield: 0.563 g (75%). The structure of the product was determined by 1H NMR (500 MHz, DMSO-d6, TMS): δ 3.65 (s, 1H), 3.5 (t, 2H, J = 2.4Hz), 2.56 (t, 2H, J = 2.3Hz), 1.52-1.57 (m, 4H), 1.5 (s, 1H), 1.41-1.44 (m, 4H); 13C NMR ( 125 MHz, DMSO): δ 62.8,34.5,32.3,28.2,24.9,24.6; ESI-MS: m/z calculated values. For C6H14OS: 134.08, measured value: 135.11 (M++1) for confirmation.
References
[1] Journal of Chemical Sciences, 2018, vol. 130, # 10,
[2] Journal of Organic Chemistry, 1999, vol. 64, # 13, p. 4959 - 4961
[3] Chemical Physics Letters, 1997, vol. 264, # 3-4, p. 376 - 380
[4] Chemistry Letters, 1996, # 8, p. 635 - 636
6-Mercaptohexan-1-ol Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14035 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 | marketing1@neostarunited.com | China | 8827 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +86-18530059196 | sale04@alfachem.cn | China | 9666 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| Chemsigma International Co., Ltd. | +86-2558742998 +86-19951791336 | info@chemsigma.com | China | 1824 | 58 |
| Dideu Industries Group Limited | +8617392712697 | 1022@dideu.com | China | 29091 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| changzhou huayang technology co., ltd | +8615250961469 | 2571773637@qq.com | China | 9628 | 58 |
View Lastest Price from 6-Mercaptohexan-1-ol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-08-06 | 6-Mercaptohexan-1-ol
1633-78-9
|
$1.00 | 1KG | 95-99% | 100kg/week | Career Henan Chemical Co |
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- 6-Mercaptohexan-1-ol
1633-78-9
- $1.00
- 95-99%
- Career Henan Chemical Co
