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D-BIOTIN P-NITROPHENYL ESTER

D-BIOTIN P-NITROPHENYL ESTER structure

CAS No.: 33755-53-2

Chemical Name:: D-BIOTIN P-NITROPHENYL ESTER

Synonyms: BNP;PBNP;BIOTIN-ONP;(+)-Biotin-ONP;Biotin-ONp Novabiochem;BIOTIN P-NITROPHENYL ESTER;Biotin π-nitrophenyl ester;4-NITROPHENYL (+)-BIOTINATE;biotinyl-4-nitrophenyl ester;D-BIOTIN P-NITROPHENYL ESTER

CBNumber:: CB1101472

Molecular Formula:: C16H19N3O5S

Molecular Weight:: 365.4

MDL Number:: MFCD15141972

MOL File:: 33755-53-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-22 18:57:36

Product description	Number	Pack Size	Price
Monoclonal Anti-NPPB antibody produced in mouse clone 2D11, purified immunoglobulin, buffered aqueous solution	WH0004879M1	100μG	$580
Monoclonal Anti-NPPB antibody produced in mouse clone 3A6F7C7, ascites fluid	SAB5300236	100μL	$580
Monoclonal Anti-NPPB antibody produced in mouse clone 9H6B4, ascites fluid	SAB5300235	100μL	$580
Brain Natriuretic Peptide EIA Kit for serum, plasma, culture supernatant and cell lysates	RAB0386	1KIT	$577
(+)-Biotin 4-nitrophenyl ester 98%	861650	100mg	$112
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D-BIOTIN P-NITROPHENYL ESTER Properties

Melting point	163-165 °C(lit.)
Boiling point	642.9±50.0 °C(Predicted)
Density	1.326±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	methanol: soluble25mg/mL, clear, colorless to greenish-yellow
pka	13.89±0.40(Predicted)
form	Solid
color	White to Off-White
biological source	mouse
optical activity	[α]25/D +51°, c = 2 in DMF: AcOH (99:1)
BRN	5795805
InChI	1S/C16H19N3O5S/c20-14(24-11-7-5-10(6-8-11)19(22)23)4-2-1-3-13-15-12(9-25-13)17-16(21)18-15/h5-8,12-13,15H,1-4,9H2,(H2,17,18,21)/t12-,13-,15-/m0/s1
InChIKey	YUDNXDTXQPYKCA-OWYJLGKBSA-N
SMILES	[O-][N+](=O)c1ccc(OC(=O)CCCC[C@@H]2SCC3NC(=O)NC23)cc1
CAS DataBase Reference	33755-53-2
UNSPSC Code	41123300
NACRES	NA.41

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS05
Signal word	Warning
Hazard statements	H290
Precautionary statements	P234-P390
PPE	Eyeshields, Gloves, type N95 (US)
Safety Statements	22-24/25
WGK Germany	3
F	10-21
HS Code	29349990
Storage Class	11 - Combustible Solids

D-BIOTIN P-NITROPHENYL ESTER price More Price(28)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	WH0004879M1	Monoclonal Anti-NPPB antibody produced in mouse clone 2D11, purified immunoglobulin, buffered aqueous solution	33755-53-2	100μG	$580	2026-04-30	Buy
Sigma-Aldrich	SAB5300236	Monoclonal Anti-NPPB antibody produced in mouse clone 3A6F7C7, ascites fluid	33755-53-2	100μL	$580	2026-04-30	Buy
Sigma-Aldrich	SAB5300235	Monoclonal Anti-NPPB antibody produced in mouse clone 9H6B4, ascites fluid	33755-53-2	100μL	$580	2026-04-30	Buy
Sigma-Aldrich	RAB0386	Brain Natriuretic Peptide EIA Kit for serum, plasma, culture supernatant and cell lysates		1KIT	$577	2026-04-30	Buy
Sigma-Aldrich	861650	(+)-Biotin 4-nitrophenyl ester 98%	33755-53-2	100mg	$112	2026-04-30	Buy

Product number	Packaging	Price	Buy
WH0004879M1	100μG	$580	Buy
SAB5300236	100μL	$580	Buy
SAB5300235	100μL	$580	Buy
RAB0386	1KIT	$577	Buy
861650	100mg	$112	Buy

D-BIOTIN P-NITROPHENYL ESTER Chemical Properties,Uses,Production

Chemical Properties

White to off-white powder

Uses

(+)-Biotin 4-nitrophenyl ester may be used in the preparation of biotin tagged ARC (adenosine-oligoarginine conjugate) derivative during cellular protein uptake studies. It may also be used to prepare biotinylated quinazoline derivatives, which shows inhibitory activities against VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinase. (+)-Biotin 4-nitrophenyl ester undergoes hydrolysis in the presence of Na[¹⁷O]H to form [¹⁷O₂]biotin, which can be used in solid-state ¹⁷O NMR spectroscopic experiments to analyze large protein-ligand complexes.

Uses

For research use only. Not for use in diagnostic procedures.
Brain natriuretic peptide EIA Kit has been used to measure brain natriuretic peptide (BNP) secreted in human neonatal ventricular cardiomyocyte culture.

General Description

The BNP Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting BNP peptide based on the principle of Competitive Enzyme Immunoassay.

reaction suitability

reaction type: Biotinylations

Biochem/physiol Actions

Brain natriuretic peptide (BNP) expressed in mammalian brain and atrial natriuretic peptide (ANP) facilitates various physiological functions including regulation of blood pressure and cardiac remodeling. BNP acts as a potential biomarker of high left ventricular end-diastolic pressure in patients with symptomatic left ventricular (LV) dysfunction. Elevated expression of BNP is observed in acute myocardial infarction (AMI) patients. BNP is also implicated in several biological functions such as diuresis, natriureis, hypotensive action and inhibition of aldosterone secretion.

Purification Methods

The ester has been recrystallised by dissolving 2g in 95% EtOH (30mL), heated to dissolve, then cooled in an ice-water bath. The crystals are collected, washed with ice-cold 95% EtOH (5mL) and dried over P2O5. The RF on silica plates (CHCl3/MeOH 19:1) is 0.19 [Bodanszky & Fagan J Am Chem Soc 99 235 1977].

Description

B-type Natriuretic Peptide Recombinant Human produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 32 amino acids and having a molecular mass of 3,500 Dalton. NPPB is purified by proprietary chromatographic techniques.

Source

Escherichia Coli

Background

Natriuretic Peptide Precursor B acts as a cardiac hormone with a variety of biological actions including natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. It is thought to play a key role in cardiovascular homeostasis. Helps restore the body's salt and water balance. Improves heart function.

D-BIOTIN P-NITROPHENYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

6-N-BIOTINYLAMINOHEXANOL

D-BIOTIN P-NITROPHENYL ESTER Suppliers

Global( 146)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shaanxi Dideu Medichem Co. Ltd	+86-029-81138252 +86-173 9270 1263	1057@dideu.com	China	4000	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29819	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9636	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32467	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10236	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23541	58

Supplier	Advantage
Shaanxi Dideu Medichem Co. Ltd	58
career henan chemical co	58
BOC Sciences	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Antai Fine Chemical Technology Co.,Limited	58
TargetMol Chemicals Inc.	58
Hubei Ipure Biology Co., Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
ANHUI WITOP BIOTECH CO., LTD	58

View Lastest Price from D-BIOTIN P-NITROPHENYL ESTER manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-22	(+)-Biotin-ONP 33755-53-2	US $0.00 / removed		99.91%	10g	TargetMol Chemicals Inc.
2024-08-15	D-BIOTIN P-NITROPHENYL ESTER 33755-53-2	US $1.00 / KG	1KG	99%	20T	Shaanxi Dideu Medichem Co. Ltd
2021-07-13	BNP 33755-53-2	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

(+)-Biotin-ONP
33755-53-2
US $0.00 / removed
99.91%
TargetMol Chemicals Inc.

D-BIOTIN P-NITROPHENYL ESTER
33755-53-2
US $1.00 / KG
99%
Shaanxi Dideu Medichem Co. Ltd

BNP
33755-53-2
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

D-BIOTIN P-NITROPHENYL ESTER Spectrum

D-BIOTIN P-NITROPHENYL ESTER(33755-53-2)MS D-BIOTIN P-NITROPHENYL ESTER(33755-53-2)¹HNMR D-BIOTIN P-NITROPHENYL ESTER(33755-53-2)IR1 D-BIOTIN P-NITROPHENYL ESTER(33755-53-2)Raman

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1of4

PBNP 4-NITROPHENYL (+)-BIOTINATE BIOTIN P-NITROPHENYL ESTER BIOTIN-ONP BNP D-BIOTIN P-NITROPHENYL ESTER BNP d-Biotin p-nitrophenyl ester D-(+)-Biotin 4-nitrophenyl ester BIOTIN-ONP D-Biotin p-nitrophenyl ester biotinyl-4-nitrophenyl ester Human B-type Natriuretic Protein 4-Nitrophenyl (+)-biotinate, d-Biotin p-nitrophenyl ester, BNP 1,1'-Binaphthyl-2,2'-diyl phosphate 4-Hydroxy-3,5-dioxa-4-phospha(V)-3H-cyclohepta[2,1-a:3,4-a']dinaphthalene-4-one 4-Hydroxy-4-oxodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin 4-Hydroxydinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-one Phosphoric acid 1,1'-binaphthalene-2,2'-diyl ester (4-nitrophenyl) 5-[(3aR,6S,6aS)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-6-yl]pentanoate 5-[(3aR,6S,6aS)-2-keto-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-6-yl]valeric acid (4-nitrophenyl) ester Biotin π-nitrophenyl ester Monoclonal Anti-NPPB antibody produced in mouse (+)-Biotin 4-nitrophenyl ester 98% BNP, D-Biotin 4-nitrophenyl ester 4-Nitrophenyl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate Biotinp-nitrophenyl ester≥ 99% (HPLC) Biotin-ONp Novabiochem (+)-Biotin4-NitrophenylEster> (+)-Biotin-ONP (+)-Biotin 4-nitrophenyl ester, 98%, (+)-Biotin 4-Nitrophenyl Ester Brain Natriuretic Peptide EIA Kit 33755-53-2 Chiral Building Blocks Asymmetric Synthesis Complex Molecules cytokine Biotin