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FMOC-VAL-OSU

FMOC-VAL-OSU structure

CAS No.: 130878-68-1

Chemical Name:: FMOC-VAL-OSU

Synonyms: 2,5-dioxopyrrolidin-1-yl (((9H-fluoren-9-yl)methoxy)carbonyl)-L-valinate;Fmoc-L-Val-OSu;Fmoc-Val-0su;Fmoc-Val-OSu;FMOC-VALINE-OSU;Fmoc-L-valine-osu;FMOC-VAL-OSUFMOC-V;Fmoc-Val-OSu, 98%, Fmoc-amino acids;N-Fmoc-L-valine N-succinimidyl ester;Trastuzumab Impurity 1 (Fmoc-Val-Osu)

CBNumber:: CB7779662

Molecular Formula:: C24H24N2O6

Molecular Weight:: 436.46

MDL Number:: MFCD00153370

MOL File:: 130878-68-1.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 03:44:26

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FMOC-VAL-OSU Properties

Density	1.35±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,2-8°C
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka	10.09±0.46(Predicted)
form	Powder
color	Off-white to white
optical activity	Consistent with structure
Water Solubility	Slightly soluble in water.

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P302+P352-P305+P351+P338-P362+P364

Safety Statements

24/25

HS Code

29251900

NFPA 704

	1
0		0

FMOC-VAL-OSU price More Price(73)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	276075	Fmoc-L-valine N-hydroxysuccinimide ester	130878-68-1	25g	$523	2026-06-03	Buy
Usbiological	276075	Fmoc-L-valine N-hydroxysuccinimide ester	130878-68-1	50g	$758	2026-06-03	Buy
Usbiological	276075	Fmoc-L-valine N-hydroxysuccinimide ester	130878-68-1	100g	$1168	2026-06-03	Buy
Usbiological	276075	Fmoc-L-valine N-hydroxysuccinimide ester	130878-68-1	250g	$2053	2026-06-03	Buy
Usbiological	276075	Fmoc-L-valine N-hydroxysuccinimide ester	130878-68-1	500g	$3433	2026-06-03	Buy

Product number	Packaging	Price	Buy
276075	25g	$523	Buy
276075	50g	$758	Buy
276075	100g	$1168	Buy
276075	250g	$2053	Buy
276075	500g	$3433	Buy

FMOC-VAL-OSU Chemical Properties,Uses,Production

Chemical Properties

White to off-white powder

Uses

N-Fmoc-L-valine N-succinimidyl ester is useful for solid phase peptide synthesis techniques.

Synthesis

6066-82-6

68858-20-8

130878-68-1

Dicyclohexylcarbodiimide (1.55 g, 7.52 mmol) and N-hydroxysuccinimide (762 mg, 6.63 mmol) were sequentially added to a stirred solution of Fmoc-L-valine (1.5 g, 4.42 mmol) in dichloromethane (25 mL) at room temperature. The reaction mixture was stirred continuously for 3 hours at room temperature. Upon completion of the reaction, the white solid dicyclohexylurea produced in the reaction was removed by filtration. The organic phase was washed sequentially with 0.1 N HCl solution and deionized water, followed by drying with anhydrous sodium sulfate. The solvent was removed by distillation under reduced pressure to give the crude product. The crude product was purified by fast column chromatography using 1% dichloromethane solution in methanol as eluent to give the final target product (S)-2,5-dioxopyrrolidin-1-yl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-methylbutyrate as a white solid (1.7 g, 89% yield). Mass spectrum (MS): m/z 459 [M + Na]+. 1H NMR (400 MHz, CDCl3) δ 7.80 (d, J = 7.5 Hz, 2H), 7.68-7.55 (m, 2H), 7.43 (t, J = 7.4 Hz, 2H), 7.34 (dd, J = 15.9, 8.5 Hz, 2H), 4.70 (d, J = 4.6 Hz, 1H), 4.56-4.40 (m, 3H), 4.28 (t, J = 6.6 Hz, 1H), 2.85 (s, 4H), 2.37 (dd, J = 12.3, 6.5 Hz, 1H), 1.08 (dd, J = 11.0, 6.9 Hz, 6H).

References

[1] Journal of Pharmaceutical Sciences, 1994, vol. 83, # 7, p. 999 - 1005
[2] Langmuir, 2010, vol. 26, # 7, p. 4990 - 4998
[3] Patent: WO2018/178060, 2018, A1. Location in patent: Page/Page column 64-66
[4] Journal of the American Chemical Society, 2015, vol. 137, # 21, p. 6932 - 6940
[5] Patent: US2017/247324, 2017, A1. Location in patent: Paragraph 0284; 0285

FMOC-VAL-OSU Preparation Products And Raw materials

Raw materials

N-Hydroxysuccinimide FMOC-L-Valine Dichloromethane Dicyclohexylcarbodiimide

Preparation Products

Val-cit-PAB-OH Fmoc-Val-Ala-PAB-OH MC-Val-Cit-PAB FMoc-Val-Cit-PAB FMoc-Val-Cit-PAB-PNP

Mc-Val-Cit-PABC-PNP

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FMOC-VAL-OSU Suppliers

Global( 167)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Beijing HwrkChemical Technology Co., Ltd	89508211 18501085097	sales.bj@hwrkchemical.com	China	9407	55
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
Beijing Ouhe Technology Co., Ltd	13552068683 13522913783	2355560935@qq.com	China	11777	60
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15350	60
Sichuan Kulinan Technology Co., Ltd	400-1166-196 18981987031	cdhxsj@163.com	China	11674	57
ChemPep, Inc.	+1 (888) 615-9178 / (561) 791-8787	service@chempep.com	United States	2138	57

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Beijing HwrkChemical Technology Co., Ltd	55
Energy Chemical	61
GL Biochem (Shanghai) Ltd	64
Beijing Ouhe Technology Co., Ltd	60
Shanghai Hanhong Scientific Co.,Ltd.	64
Chemsky (shanghai) International Co.,Ltd	60
Sichuan Kulinan Technology Co., Ltd	57
ChemPep, Inc.	57

View Lastest Price from FMOC-VAL-OSU manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-11	Fmoc-L-Val-Osu 130878-68-1		1kg	98%	1T+	Sichuan HongRi Pharma-Tech Co.,Ltd
2026-08-13	FMOC-VAL-OSU 130878-68-1		1KG	98%	2000	Shenzhen Nexcon Pharmatechs Ltd.
2020-01-06	fmoc-val-osu 130878-68-1	$1.00	1g	98%	100KG	Sichuan Jiaying Lai Technology Co.,LTD

Fmoc-L-Val-Osu
130878-68-1
98%
Sichuan HongRi Pharma-Tech Co.,Ltd

FMOC-VAL-OSU
130878-68-1
98%
Shenzhen Nexcon Pharmatechs Ltd.

fmoc-val-osu
130878-68-1
$1.00
98%
Sichuan Jiaying Lai Technology Co.,LTD

130878-68-1(FMOC-VAL-OSU)Related Search:

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CarbaMic acid, [1-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-2-Methylpropyl]-, 9H-fluoren-9-ylMethyl ester, (S)- L-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-,2,5-dioxo-1-pyrrolidinyl ester N-Fmoc-L-valine N-succinimidyl ester Fmoc-L-valineN-hydroxysuccinimide ester≥ 99% (HPLC) FMOC-L-VALINE N-HYDROXYSUCCINIMIDE ESTER FMOC-VALINE-OSU NALPHA-9-Fluorenylmethoxycarbonyl-L-valine N-hydroxysuccinimide ester N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-valine succinimidyl ester (S)-2,5-dioxopyrrolidin-1-yl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-methylbutanoate N-alpha-FMoc-L-valine N-hydroxysucciniMide ester [(1S)-1-[[(2,5-Dioxo-1-pyrrolidinyl)oxy]carbonyl]-2-methylpropyl] 9H-fluoren-9-ylmethyl carbamate N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valine 2,5-dioxo-1-pyrrolidinyl ester (9H-Fluoren-9-yl)MethOxy]Carbonyl Val-OSu Fmoc-Val-OSu, 98%, Fmoc-amino acids FMOC-VAL-OSUFMOC-V 2,5-dioxopyrrolidin-1-yl (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylbutanoate N-Fmoc-L-valineN-succinimidylester,95% Fmoc-L-valine-osu Trastuzumab Impurity 1 (Fmoc-Val-Osu) Fmoc-Val-0su 2,5-dioxopyrrolidin-1-yl (((9H-fluoren-9-yl)methoxy)carbonyl)-L-valinate Fmoc-L-Val-OSu Fmoc-Val-OSu 130878-68-1 Fmoc-Amino Acids and Derivatives Fmoc-Amino acid series Amino Acids