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ChemicalBook >> CAS DataBase List >>2,4(1H,3H)-Pyrimidinedione, 3-[3-[4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]-1-piperazinyl]propyl]-5-methyl-

2,4(1H,3H)-Pyrimidinedione, 3-[3-[4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]-1-piperazinyl]propyl]-5-methyl-

2,4(1H,3H)-Pyrimidinedione, 3-[3-[4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]-1-piperazinyl]propyl]-5-methyl- Structure
2,4(1H,3H)-Pyrimidinedione, 3-[3-[4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]-1-piperazinyl]propyl]-5-methyl- structure
CAS No.
186386-21-0
Chemical Name:
2,4(1H,3H)-Pyrimidinedione, 3-[3-[4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]-1-piperazinyl]propyl]-5-methyl-
Synonyms
Ro 70 0004,Ro700004;2,4(1H,3H)-Pyrimidinedione, 3-[3-[4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]-1-piperazinyl]propyl]-5-methyl-
CBNumber:
CB78354933
Molecular Formula:
C20H24F4N4O3
Molecular Weight:
444.42
MDL Number:
MFCD00954691
MOL File:
186386-21-0.mol
Last updated:2026-05-11 15:21:01
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2,4(1H,3H)-Pyrimidinedione, 3-[3-[4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]-1-piperazinyl]propyl]-5-methyl- Properties

Density 1.300±0.06 g/cm3(Predicted)
pka 10.61±0.10(Predicted)
FDA UNII 3AK2RKG763

2,4(1H,3H)-Pyrimidinedione, 3-[3-[4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]-1-piperazinyl]propyl]-5-methyl- Chemical Properties, Uses, Production

Uses

Ro 70-0004 (RS-100975) is a selective alpha1A-adrenoceptor antagonist with a pKi of 8.9. Ro 70‐0004 can be used in the study of prostatic hyperplasia[1].

IC 50

Alpha-1A adrenergic receptor: 8.9 (pKi)

References

[1] Williams TJ, et al. In vitro alpha1-adrenoceptor pharmacology of Ro 70-0004 and RS-100329, novel alpha1A-adrenoceptor selective antagonists. Br J Pharmacol. 1999 May;127(1):252-8. DOI:10.1038/sj.bjp.0702541

2,4(1H,3H)-Pyrimidinedione, 3-[3-[4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]-1-piperazinyl]propyl]-5-methyl- Preparation Products And Raw materials

Raw materials

Preparation Products

2,4(1H,3H)-Pyrimidinedione, 3-[3-[4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]-1-piperazinyl]propyl]-5-methyl- Suppliers

Global Suppliers ( 4)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Suzhou Meishi Biotechnology Co., Ltd. 1173954148q meishipharma@126.com China 20027 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
TargetMol Chemicals Inc. 58
Suzhou Meishi Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Latest Price from 2,4(1H,3H)-Pyrimidinedione, 3-[3-[4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]-1-piperazinyl]propyl]-5-methyl- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ro-70-0004 pictures 2026-05-11 Ro-70-0004
186386-21-0
 $1820.00-3100.00 10g TargetMol Chemicals Inc.
  • Ro-70-0004 pictures
  • Ro-70-0004
    186386-21-0
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186386-21-0 (2,4(1H,3H)-Pyrimidinedione, 3-[3-[4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]-1-piperazinyl]propyl]-5-methyl-) Related Search:

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2,4(1H,3H)-Pyrimidinedione, 3-[3-[4-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]-1-piperazinyl]propyl]-5-methyl- Ro 70 0004,Ro700004 186386-21-0 C20H24F4N4O3