4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE
- CAS No.
- 2770-01-6
- Chemical Name:
- 4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE
- Synonyms
- 4-CHLORO-1-H-IMIDAZO[4;4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE;3H-IMidazo[4,5-c]pyridine, 4-chloro-;4-Chloro-1H-imidazo[4,5-c]pyridine 98%;4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE ISO 9001:2015 REACH;4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE
- CBNumber:
- CB7840366
- Molecular Formula:
- C6H4ClN3
- Molecular Weight:
- 153.57
- MDL Number:
- MFCD08689582
- MOL File:
- 2770-01-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Chloro-1H-imidazo[4,5-c]pyridine Asreported | 269073 | 100mg | $319 |
| 4-Chloro-1H-imidazo[4,5-c]pyridine Asreported | 269073 | 250mg | $428 |
| 4-Chloro-1H-imidazo[4,5-c]pyridine Asreported | 269073 | 500mg | $566 |
| 4-Chloro-1H-imidazo[4,5-c]pyridine Asreported | 269073 | 1g | $758 |
| 4-Chloro-1H-imidazo[4,5-c]pyridine Asreported | 269073 | 2g | $1027 |
| More product size | |||
| Melting point | 179-181 °C |
|---|---|
| Boiling point | 455.4±25.0 °C(Predicted) |
| Density | 1.531±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | DMSO (Slightly, Sonicated), Methanol (Slightly, Sonicated) |
| form | Solid |
| pka | 7.93±0.40(Predicted) |
| color | Pale Beige to Pale Brown |
| InChI | InChI=1S/C6H4ClN3/c7-6-5-4(1-2-8-6)9-3-10-5/h1-3H,(H,9,10) |
| InChIKey | DHJMLXBBZRWBPW-UHFFFAOYSA-N |
| SMILES | C1(Cl)=NC=CC2N=CNC1=2 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933399990 |
4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE price More Price(55)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 269073 | 4-Chloro-1H-imidazo[4,5-c]pyridine Asreported | 2770-01-6 | 100mg | $319 | 2026-06-03 | Buy |
| Usbiological | 269073 | 4-Chloro-1H-imidazo[4,5-c]pyridine Asreported | 2770-01-6 | 250mg | $428 | 2026-06-03 | Buy |
| Usbiological | 269073 | 4-Chloro-1H-imidazo[4,5-c]pyridine Asreported | 2770-01-6 | 500mg | $566 | 2026-06-03 | Buy |
| Usbiological | 269073 | 4-Chloro-1H-imidazo[4,5-c]pyridine Asreported | 2770-01-6 | 1g | $758 | 2026-06-03 | Buy |
| Usbiological | 269073 | 4-Chloro-1H-imidazo[4,5-c]pyridine Asreported | 2770-01-6 | 2g | $1027 | 2026-06-03 | Buy |
4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE Chemical Properties,Uses,Production
Uses
4-Chloro-1H-imidazo[4,5-c]pyridine is used as a reagent in the synthesis of 3-bromo-3-deazaneplanocin and 3-bromo-3-deazaaristeromycin, compounds which exhibit antiviral activity.
Synthesis
91184-02-0
2770-01-6
The general procedure for the synthesis of 4-chloroimidazo[4,5-C]pyridine using the compound (CAS: 91184-02-0) as starting material was as follows: compound 3 (255 mg, 1.88 mmol) was dissolved in 10 mL of phosphorus oxytrichloride (POCl3), and the reaction was stirred for 3 hr at 110 °C until the reaction solution became clear. Upon completion of the reaction, the excess phosphorous trichloride was removed under vacuum. Subsequently, ice water was added to the reaction mixture, the pH was adjusted to about 9 by slowly adding ammonia dropwise, and an equal volume of methanol (MeOH) was added. At this point, a precipitate appeared in the reaction mixture and the precipitate was collected by filtration. The filtrate was adsorbed on silica gel and purified by silica gel column chromatography, the eluent being a mixture of ethyl acetate (EA) and 5% methanol (MeOH), resulting in the target product 4 in 83% yield. The results of high-resolution mass spectrometry (HRMS-ESI) analysis were as follows: m/z calculated value (C6H5ClN3 [M+H]+) was 154.0166, and the measured value was 154.0171.
References
[1] European Journal of Medicinal Chemistry, 2018, vol. 148, p. 384 - 396
[2] ChemMedChem, 2013, vol. 8, # 6, p. 985 - 993
[3] Patent: US5057517, 1991, A



4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32997 | 60 |
| Accela ChemBio Inc. | +1-858-6993322 +86-18019713315 | info@accelachem.com | United States | 21189 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21135 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| KARMEL TECHNOLOGY (HK) CO.,LIMITED | +8618795957998 | karmelhk@126.com | CHINA | 2886 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1059@dideu.com | China | 29096 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9897 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
View Lastest Price from 4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-11-18 | 4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE
2770-01-6
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited |
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![4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE pictures](/ProductImageEN/2021-10/Small/aa1f852c-5fea-4212-acfa-dbdee5f90a66.jpg)
- 4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE
2770-01-6
- $1.10
- 99.00%
- Dideu Industries Group Limited
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