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4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE

CAS No.
2770-01-6
Chemical Name:
4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE
Synonyms
4-CHLORO-1-H-IMIDAZO[4;4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE;3H-IMidazo[4,5-c]pyridine, 4-chloro-;4-Chloro-1H-imidazo[4,5-c]pyridine 98%;4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE ISO 9001:2015 REACH;4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE
CBNumber:
CB7840366
Molecular Formula:
C6H4ClN3
Molecular Weight:
153.57
MDL Number:
MFCD08689582
MOL File:
2770-01-6.mol
MSDS File:
SDS
Last updated:2026-05-28 05:07:27
Product description Number Pack Size Price
4-Chloro-1H-imidazo[4,5-c]pyridine Asreported 269073 100mg $319
4-Chloro-1H-imidazo[4,5-c]pyridine Asreported 269073 250mg $428
4-Chloro-1H-imidazo[4,5-c]pyridine Asreported 269073 500mg $566
4-Chloro-1H-imidazo[4,5-c]pyridine Asreported 269073 1g $758
4-Chloro-1H-imidazo[4,5-c]pyridine Asreported 269073 2g $1027
More product size

4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE Properties

Melting point 179-181 °C
Boiling point 455.4±25.0 °C(Predicted)
Density 1.531±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility DMSO (Slightly, Sonicated), Methanol (Slightly, Sonicated)
form Solid
pka 7.93±0.40(Predicted)
color Pale Beige to Pale Brown
InChI InChI=1S/C6H4ClN3/c7-6-5-4(1-2-8-6)9-3-10-5/h1-3H,(H,9,10)
InChIKey DHJMLXBBZRWBPW-UHFFFAOYSA-N
SMILES C1(Cl)=NC=CC2N=CNC1=2

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933399990

4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE price More Price(55)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 269073 4-Chloro-1H-imidazo[4,5-c]pyridine Asreported 2770-01-6 100mg $319 2026-06-03 Buy
Usbiological 269073 4-Chloro-1H-imidazo[4,5-c]pyridine Asreported 2770-01-6 250mg $428 2026-06-03 Buy
Usbiological 269073 4-Chloro-1H-imidazo[4,5-c]pyridine Asreported 2770-01-6 500mg $566 2026-06-03 Buy
Usbiological 269073 4-Chloro-1H-imidazo[4,5-c]pyridine Asreported 2770-01-6 1g $758 2026-06-03 Buy
Usbiological 269073 4-Chloro-1H-imidazo[4,5-c]pyridine Asreported 2770-01-6 2g $1027 2026-06-03 Buy
Product number Packaging Price Buy
269073 100mg $319 Buy
269073 250mg $428 Buy
269073 500mg $566 Buy
269073 1g $758 Buy
269073 2g $1027 Buy

4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE Chemical Properties,Uses,Production

Uses

4-Chloro-1H-imidazo[4,5-c]pyridine is used as a reagent in the synthesis of 3-bromo-3-deazaneplanocin and 3-bromo-3-deazaaristeromycin, compounds which exhibit antiviral activity.

Synthesis

3H-IMidazo[4,5-c]pyridine, 5-oxide

91184-02-0

4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE

2770-01-6

The general procedure for the synthesis of 4-chloroimidazo[4,5-C]pyridine using the compound (CAS: 91184-02-0) as starting material was as follows: compound 3 (255 mg, 1.88 mmol) was dissolved in 10 mL of phosphorus oxytrichloride (POCl3), and the reaction was stirred for 3 hr at 110 °C until the reaction solution became clear. Upon completion of the reaction, the excess phosphorous trichloride was removed under vacuum. Subsequently, ice water was added to the reaction mixture, the pH was adjusted to about 9 by slowly adding ammonia dropwise, and an equal volume of methanol (MeOH) was added. At this point, a precipitate appeared in the reaction mixture and the precipitate was collected by filtration. The filtrate was adsorbed on silica gel and purified by silica gel column chromatography, the eluent being a mixture of ethyl acetate (EA) and 5% methanol (MeOH), resulting in the target product 4 in 83% yield. The results of high-resolution mass spectrometry (HRMS-ESI) analysis were as follows: m/z calculated value (C6H5ClN3 [M+H]+) was 154.0166, and the measured value was 154.0171.

References

[1] European Journal of Medicinal Chemistry, 2018, vol. 148, p. 384 - 396
[2] ChemMedChem, 2013, vol. 8, # 6, p. 985 - 993
[3] Patent: US5057517, 1991, A

39217-08-8
149-73-5
2770-01-6
Synthesis of 4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE from 2-Chloro-3,4-diaminopyridine and Trimethoxymethane
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View Lastest Price from 4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE  pictures 2025-11-18 4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE
2770-01-6
$1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited

4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE Spectrum

3H-IMidazo[4,5-c]pyridine, 4-chloro- 4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE 4-Chloro-1H-imidazo[4,5-c]pyridine 98% 4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE 4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE ISO 9001:2015 REACH 4-CHLORO-1-H-IMIDAZO[4 2770-01-6 2770-1-6 Heterocycle-Pyridine series