2-Oxazolecarbonitrile
- CAS No.
- 68776-60-3
- Chemical Name:
- 2-Oxazolecarbonitrile
- Synonyms
- 2-CYANO-OXAZOLE;2-Oxazolecarbonitrile;oxazole-2-carbonitrile;1,3-oxazole-2-carbonitrile
- CBNumber:
- CB7841994
- Molecular Formula:
- C4H2N2O
- Molecular Weight:
- 94.07
- MDL Number:
- MFCD08669511
- MOL File:
- 68776-60-3.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H300-H311+H331 |
| Precautionary statements | P261-P264-P280-P301+P310 |
2-Oxazolecarbonitrile price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | 57346 | 2-CYANO-OXAZOLE 97% | 68776-60-3 | 0.25G | $127 | 2026-04-30 | Buy |
| AstaTech | 57346 | 2-CYANO-OXAZOLE 97% | 68776-60-3 | 1G | $273 | 2026-04-30 | Buy |
| AstaTech | 57346 | 2-CYANO-OXAZOLE 97% | 68776-60-3 | 5G | $884 | 2026-04-30 | Buy |
| Activate Scientific | AS280024 | Oxazole-2-carbonitrile 98% | 68776-60-3 | 250mg | $234 | 2026-06-04 | Buy |
| Activate Scientific | AS280024 | Oxazole-2-carbonitrile 98% | 68776-60-3 | 1g | $424 | 2026-06-04 | Buy |
2-Oxazolecarbonitrile Chemical Properties, Uses, Production
Synthesis
884539-45-1
68776-60-3
Example 112: Synthesis of 1,3-oxazole-2-carbonitrile; 1,3-oxazole-2-carboxamide (0.98 g, 8.8 mmol, 1.0 eq.) was dissolved in pyridine (17 mL), followed by the addition of phosphorus triclosan (1.2 mL, 12.2 mmol, 1.4 eq.). The reaction mixture was stirred at room temperature for 5 h. The solution was observed to change from a beige slurry to a brown color. After completion of the reaction, the mixture was diluted with ice water and extracted with ether. The aqueous layer was adjusted to pH 3 with 6 M hydrochloric acid and extracted again with ether. The combined ether extracts were washed sequentially with water and saturated brine, dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to give 1,3-oxazole-2-carbonitrile as an amber colored oil (0.61 g, 74% yield). The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 8.608 (s, 1H), 7.67 (s, 1H).
References
[1] Patent: WO2006/43145, 2006, A1. Location in patent: Page/Page column 131
[2] Patent: WO2010/45009, 2010, A1. Location in patent: Page/Page column 40-41
[3] Patent: WO2010/45015, 2010, A1. Location in patent: Page/Page column 27
[4] Patent: WO2010/45016, 2010, A1. Location in patent: Page/Page column 20
2-Oxazolecarbonitrile Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| China DongFan Chemical Co.,LTD | 86-0571-85151182 | China | 5681 | 66 | |
| Jinan Trio PharmaTech Co., Ltd. | 0531-88811783 | sales@trio-pharmatech.com | China | 1856 | 62 |
| Shanghai Carlow Chemicals Co., Ltd. | 21-33526724 18930996265 | info@carlowchem.com | China | 1996 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66028182 17714375163 | yftan@aikonchem.com | China | 16674 | 50 |
| JW & Y Pharmlab Co., Ltd. | 021-64340559 | xinyu_shi@jwypharmlab.com.cn | China | 11999 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Shanghai Huaxing Biological Technology Co., Ltd. | 18621295758; 18621295758 | 1449085402@qq.com | China | 1973 | 55 |
| Wuxi AppTec | 022-59987777 13552403979 | jia_guoqiang@wuxiapptec.com | China | 22344 | 58 |
| SHANGHAI FDC-CHEMICAL CO.,LTD | 021-61469567 13774476675 | sales@fdc-chemical.com | China | 10000 | 58 |
| Wuhan FengyaoTonghui Chemical Products Co., Ltd. | 027-87466105 15377573527 | 2678564200@qq.com | China | 17968 | 58 |
