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3,5-DIFLUORO-4-HYDROXY-BENZONITRILE

3,5-DIFLUORO-4-HYDROXY-BENZONITRILE structure

CAS No.: 2967-54-6

Chemical Name:: 3,5-DIFLUORO-4-HYDROXY-BENZONITRILE

Synonyms: 3,5-DIFLUORO-4-HYDROXY-BENZONITRILE;Benzonitrile, 3,5-difluoro-4-hydroxy-;3,5-Difluoro-4-hydroxybenzonitrile,97%

CBNumber:: CB7843741

Molecular Formula:: C7H3F2NO

Molecular Weight:: 155.1

MDL Number:: MFCD09033181

MOL File:: 2967-54-6.mol

MSDS File:: SDS

Last updated:2026-05-28 05:10:28

Product description	Number	Pack Size	Price
3,5-Difluoro-4-hydroxybenzonitrile 98%	PC201222	100mg	$21
3,5-Difluoro-4-hydroxybenzonitrile 98%	PC201222	250mg	$24
3,5-Difluoro-4-hydroxybenzonitrile 98%	PC201222	1g	$40
3,5-Difluoro-4-hydroxybenzonitrile 98%	PC201222	5g	$141
3,5-Difluoro-4-hydroxybenzonitrile 98%	PC201222	25g	$549
More product size

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3,5-DIFLUORO-4-HYDROXY-BENZONITRILE Properties

Melting point	200-208℃
Boiling point	221.0±40.0 °C(Predicted)
Density	1.44±0.1 g/cm3(Predicted)
storage temp.	Storage temp. 2-8°C
pka	5.34±0.23(Predicted)
Appearance	White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Danger

Hazard statements

H302-H312-H315-H319-H332

Precautionary statements

P261-P280-P301+P312a-P304+P340-P305+P351+P338-P501a

HazardClass

6.1

HS Code

2926907090

NFPA 704

	1
2		0

3,5-DIFLUORO-4-HYDROXY-BENZONITRILE price More Price(49)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Apolloscientific	PC201222	3,5-Difluoro-4-hydroxybenzonitrile 98%	2967-54-6	100mg	$21	2026-06-04	Buy
Apolloscientific	PC201222	3,5-Difluoro-4-hydroxybenzonitrile 98%	2967-54-6	250mg	$24	2026-06-04	Buy
Apolloscientific	PC201222	3,5-Difluoro-4-hydroxybenzonitrile 98%	2967-54-6	1g	$40	2026-06-04	Buy
Apolloscientific	PC201222	3,5-Difluoro-4-hydroxybenzonitrile 98%	2967-54-6	5g	$141	2026-06-04	Buy
Apolloscientific	PC201222	3,5-Difluoro-4-hydroxybenzonitrile 98%	2967-54-6	25g	$549	2026-06-04	Buy

Product number	Packaging	Price	Buy
PC201222	100mg	$21	Buy
PC201222	250mg	$24	Buy
PC201222	1g	$40	Buy
PC201222	5g	$141	Buy
PC201222	25g	$549	Buy

3,5-DIFLUORO-4-HYDROXY-BENZONITRILE Chemical Properties,Uses,Production

Uses

3,5-Difluoro-4-hydroxybenzonitrile

Synthesis

Benzaldehyde, 3,5-difluoro-4-hydroxy-, oxime, [C(E)]-

960287-97-2

2967-54-6

The general procedure for the synthesis of 3,5-difluoro-4-hydroxybenzonitrile from 3,5-difluoro-4-hydroxybenzaldehyde oxime is as follows: to a solution of tetrahydrofuran (THF, 10 mL) containing the aldoxime (0.01 mol) was added T3P (15 mol%, 50% solution in ethyl acetate (EtOAc)). The reaction mixture was stirred at room temperature for 1-2 h under nitrogen protection. The progress of the reaction was monitored by thin layer chromatography (TLC) and after confirming the completion of the reaction, the solvent was removed under reduced pressure. The residue was diluted with distilled water (20 mL) and subsequently extracted with ethyl acetate (2 x 20 mL). The organic phases were combined and washed sequentially with saturated sodium bicarbonate (NaHCO3) solution (10 mL) and brine. The organic phase was dried over anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure to afford the target product 3,5-difluoro-4-hydroxybenzonitrile of high purity.

References

[1] Tetrahedron Letters, 2011, vol. 52, # 10, p. 1074 - 1077

3,5-DIFLUORO-4-HYDROXY-BENZONITRILE synthesis

Synthesis of 3,5-DIFLUORO-4-HYDROXY-BENZONITRILE from 3,5-DIFLUORO-4-METHOXYBENZONITRILE

3,5-DIFLUORO-4-HYDROXY-BENZONITRILE Preparation Products And Raw materials

Raw materials

4-Bromo-2,6-difluorophenol 3,5-DIFLUORO-4-METHOXYBENZONITRILE 3,5-Difluoro-4-hydroxybenzaldehyde Copper(I) Cyanide Benzaldehyde, 3,5-difluoro-4-hydroxy-, oxime, [C(E)]-

Ethyl acetate Propylphosphonic anhydride Tetrahydrofuran

1of2

Preparation Products

3-Fluoro-4-hydroxybenzonitrile

3,5-DIFLUORO-4-HYDROXY-BENZONITRILE Suppliers

Global( 80)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29812	58
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10000	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Changzhou Anxuan Chemical Co., Ltd	+86-0519-89882563 +86-18961279162	andy@anxuanchem.com	China	4327	58
Aromsyn Co., Ltd.	+86-0571-85585865 +8613336024896	CB@aromsyn.com	China	19183	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
Compound Net Biotechnology Inc.	+8615303909093	sales@compound-net.com	China	2914	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
career henan chemical co	58
Changzhou Ansciep Chemical Co., Ltd.	58
Fuxin Pharmaceutical	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Changzhou Anxuan Chemical Co., Ltd	58
Aromsyn Co., Ltd.	58
Aladdin Scientific	58
Compound Net Biotechnology Inc.	58

View Lastest Price from 3,5-DIFLUORO-4-HYDROXY-BENZONITRILE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-07-06	3,5-DIFLUORO-4-HYDROXY-BENZONITRILE 2967-54-6	$1.00	1KG	98%	200kg	Career Henan Chemical Co

3,5-DIFLUORO-4-HYDROXY-BENZONITRILE
2967-54-6
$1.00
98%
Career Henan Chemical Co

3,5-DIFLUORO-4-HYDROXY-BENZONITRILE Spectrum

3,5-DIFLUORO-4-HYDROXY-BENZONITRILE(2967-54-6)¹HNMR

2967-54-6(3,5-DIFLUORO-4-HYDROXY-BENZONITRILE)Related Search:

BISMERTHIAZOL 4-METHOXY-2,3,5-TRIFLUOROBENZONITRILE 3-Fluoro-4-hydroxybenzonitrile 3,5-DIFLUORO-4-METHOXYBENZONITRILE 3,5-DIFLUORO-4-HYDROXY-BENZONITRILE

3,5-DIFLUORO-4-HYDROXY-BENZONITRILE Benzonitrile, 3,5-difluoro-4-hydroxy- 3,5-Difluoro-4-hydroxybenzonitrile,97% 2967-54-6