tert-Butyl 6-aminopyridin-2-ylcarbamate
- CAS No.
- 322690-31-3
- Chemical Name:
- tert-Butyl 6-aminopyridin-2-ylcarbamate
- Synonyms
- 2-Amino-6-(Boc-amino)pyridine;tert-Butyl 6-aminopyridin-2-ylcarbamate;tert-butyl N-(6-amino-2-pyridyl)carbamate;tert-Butyl N-(6-amino-2-pyridinyl)carbamate;tert-butyl N-(6-aminopyridin-2-yl)carbamate;2-Amino-6-(tert-butoxycarbonylamino)pyridine;2-Amino-6-(tert-butoxycarbonylamino)pyridine >tert-Butyl N-(6-amino-2-pyridinyl)carbamate 95+%;2-Amino-6-(tert-butoxycarbonylamino)pyridine;(6-Aminopyridin-2-yl)carbamic acid tert-butyl ester
- CBNumber:
- CB7846595
- Molecular Formula:
- C10H15N3O2
- Molecular Weight:
- 209.24
- MDL Number:
- MFCD09037865
- MOL File:
- 322690-31-3.mol
| Melting point | 125.0 to 129.0 °C |
|---|---|
| Boiling point | 307.1±27.0 °C(Predicted) |
| Density | 1.202±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 12.26±0.70(Predicted) |
| color | White to Light yellow |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Risk Statements | 43 | |||||||||
| Safety Statements | 36/37 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
tert-Butyl 6-aminopyridin-2-ylcarbamate price More Price(48)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | A2708 | 2-Amino-6-(tert-butoxycarbonylamino)pyridine >97.0%(T) | 322690-31-3 | 1g | $104 | 2024-03-01 | Buy |
| TCI Chemical | A2708 | 2-Amino-6-(tert-butoxycarbonylamino)pyridine >97.0%(T) | 322690-31-3 | 5g | $354 | 2024-03-01 | Buy |
| Apolloscientific | OR303672 | tert-Butyl N-(6-amino-2-pyridinyl)carbamate 97% | 322690-31-3 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR303672 | tert-Butyl N-(6-amino-2-pyridinyl)carbamate 97% | 322690-31-3 | 1g | $24 | 2026-06-04 | Buy |
| Apolloscientific | OR303672 | tert-Butyl N-(6-amino-2-pyridinyl)carbamate 97% | 322690-31-3 | 5g | $105 | 2026-06-04 | Buy |
tert-Butyl 6-aminopyridin-2-ylcarbamate Chemical Properties, Uses, Production
Uses
tert-Butyl 6-Aminopyridin-2-ylcarbamate is used in preparation of novel Macrocyclic Diacetylene compounds.Also, used in preparation of substituted Bicyclic Aza-Heterocycles and analogs as Sirtuin modulators.
Synthesis
141-86-6
24424-99-5
322690-31-3
2,6-diaminopyridine (5.00 g, 45.82 mmol) and di-tert-butyl dicarbonate ((Boc)2O) (10.99 g, 50.40 mmol) were used as raw materials and reacted in tetrahydrofuran (THF) (200 mL). 2,6-diaminopyridine was first dissolved in THF, followed by the addition of (Boc)2O, and the reaction was stirred for 12 h at room temperature. After completion of the reaction, the reaction mixture was poured into saturated aqueous sodium bicarbonate solution and the solid was collected by filtration. Purification was carried out by column chromatography (eluent ratio methanol: dichloromethane= 0.5:9.5) to give 5.2 g of 2-amino-6-(tert-butoxycarbonylamino)pyridine (compound j1) in 54% yield.
References
[1] Chemical Communications, 2008, # 35, p. 4126 - 4128
[2] Chemistry - A European Journal, 2001, vol. 7, # 13, p. 2798 - 2809
[3] Chemistry - A European Journal, 2007, vol. 13, # 19, p. 5466 - 5479
[4] Patent: KR2018/9249, 2018, A. Location in patent: Paragraph 0228; 0229
[5] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 13, p. 3493 - 3497
tert-Butyl 6-aminopyridin-2-ylcarbamate Preparation Products And Raw materials
tert-Butyl 6-aminopyridin-2-ylcarbamate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| future industrial shanghai co., ltd | 400-0066400 13621662912 | sales@jonln.com | China | 1989 | 65 |
| Shanghai Targsense Scientific Co., Ltd. | 18916626092 | targsense@qq.com | China | 110 | 65 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shanghai Ennopharm Co., Ltd. | +86 (21) 6435-5022 | China | 4263 | 65 | |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9510 | 58 |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7545 | 61 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
| TCI Europe | 320-37350700 | sales@tcieurope.eu | Europe | 23654 | 75 |
| TCI AMERICA | 800-4238616 | sales@tciamerica.com | Americas | 23636 | 75 |
View Latest Price from tert-Butyl 6-aminopyridin-2-ylcarbamate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-19 | TERT-BUTYL 6-AMINOPYRIDIN-2-YLCARBAMATE
322690-31-3
|
$3.00 | 1KG | 98% | 1kg,5kg,50kg | Career Henan Chemical Co |
-
- TERT-BUTYL 6-AMINOPYRIDIN-2-YLCARBAMATE
322690-31-3
- $3.00
- 98%
- Career Henan Chemical Co
