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1,8-Naphthalic anhydride

1,8-Naphthalic anhydride Structure
1,8-Naphthalic anhydride structure
CAS No.
81-84-5
Chemical Name:
1,8-Naphthalic anhydride
Synonyms
1H,3H-BENZO[DE]ISOCHROMENE-1,3-DIONE;NAPHTHALIC ANHYDRIDE;Benzo[de]isochromene-1,3-dione;1,8-Napthalic anhydride;Naphthalene-1,8-dicarboxylic anhydride;Protect;1,8-Naphthalic;Naphthalic acid anhydride;1,8 Naphthaloic Anhydride;1,8-NAPHTHALENEDICARBOXYLIC ANHYDRIDE
CBNumber:
CB7854433
Molecular Formula:
C12H6O3
Molecular Weight:
198.17
MDL Number:
MFCD00006925
MOL File:
81-84-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-31 15:25:14
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1,8-Naphthalic anhydride Properties

Melting point 269 °C
Boiling point 295.48°C (rough estimate)
Density 1.2571 (rough estimate)
vapor pressure 0Pa at 25℃
refractive index 1.5550 (estimate)
Flash point 272 °C
storage temp. Store below +30°C.
solubility Chloroform (Slightly, Heated), DMSO
form Powder
color Beige to light brown
Water Solubility decomposes
Sensitive Moisture Sensitive
BRN 153190
Henry's Law Constant 1.6×101 mol/(m3Pa) at 25℃, HSDB (2015)
InChI 1S/C12H6O3/c13-11-8-5-1-3-7-4-2-6-9(10(7)8)12(14)15-11/h1-6H
InChIKey GRSMWKLPSNHDHA-UHFFFAOYSA-N
SMILES O=C1OC(=O)c2cccc3cccc1c23
LogP 3.24
Surface tension 72.5mN/m at 1.3mg/L and 20℃
CAS DataBase Reference 81-84-5(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 32RS852X55
NIST Chemistry Reference 1,8-Naphthalic anhydride(81-84-5)
EPA Substance Registry System 1,8-Naphthalic anhydride (81-84-5)
UNSPSC Code 12162002
NACRES NA.23

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
Signal word  Warning
Hazard statements  H315-H319-H228
Precautionary statements  P240-P210-P241-P264-P280-P302+P352-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39-24/25
WGK Germany  2
RTECS  QK5350000
F  21
TSCA  TSCA listed
HS Code  29173980
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Hazardous Substances Data 81-84-5(Hazardous Substances Data)
REACH Registrations Active
NFPA 704
1
1 0

1,8-Naphthalic anhydride price More Price(44)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich N1607 1,8-Naphthalic anhydride 81-84-5 100g $52.4 2026-04-30 Buy
Sigma-Aldrich N1607 1,8-Naphthalic anhydride 81-84-5 500g $145 2026-04-30 Buy
TCI Chemical N0022 1,8-Naphthalic Anhydride >98.0%(T)(HPLC) 81-84-5 25g $29 2026-04-30 Buy
TCI Chemical N0022 1,8-Naphthalic Anhydride >98.0%(T)(HPLC) 81-84-5 250g $52 2026-04-30 Buy
TRC TRC-N345300-500G 1,8-Naphthoic Anhydride 81-84-5 500g $127 2026-06-03 Buy
Product number Packaging Price Buy
N1607 100g $52.4 Buy
N1607 500g $145 Buy
N0022 25g $29 Buy
N0022 250g $52 Buy
TRC-N345300-500G 500g $127 Buy

1,8-Naphthalic anhydride Chemical Properties, Uses, Production

Chemical Properties

BEIGE TO LIGHT BROWN POWDER

Uses

Dyestuffs, organic synthesis in general.

Uses

1,8-Naphthalic anhydride is used as a seed protectant and to prepare dyestuffs and optical brighteners. It is used in the preparation of napthalimide analogues, which finds application as anticancer agents. Further, it is used as fluorescent brightening agent for polymeric materials.

Definition

ChEBI: Naphthalic anhydride is a cyclic dicarboxylic anhydride.

Production Methods

No public source provides a proprietary industrial synthesis for nahthalic anhydride. However, its production can be inferred from its chemical structure. Industrial manufacture would typically begins with oxidation of naphthalene to form 1,8 naphthalic acid, followed by intramolecular dehydration to generate the anhydride ring system, steps consistent with the way 1,8 naphthalic anhydride is produced as a chemical intermediate in the dye and agrochemical industries. After cyclodehydration, the crude anhydride would be purified through controlled heating, solvent washing, and crystallisation to achieve the high purity required for use as a safener in seed treatment formulations.

Mechanism of action

Enhances cytochrome P450-mediated oxidative metabolism of the herbicide

Purification Methods

Extract it with cold aqueous Na2CO3 to remove free acid, then crystallise from acetic anhydride. [Beilstein 17 III/IV 6392, 17/11 V 492.]

Pesticide Type

Semiochemical

1,8-Naphthalic anhydride Preparation Products And Raw materials

Raw materials

Acenaphthene

Preparation Products

1-Amino-8-naphthoic acid 3,4,9,10-Perylenetetracarboxylic dianhydride Solvent Yellow 98 1,8-Naphthalic acid Transparent Red E2G
Fluorescent Yellow Ii (Disperse) SOLVENT YELLOW 85 fluorescent whitening agent EFR Vat Grey BG Pigment Red 190
1,8-Dimethylnaphthalene 3,9-perylenedicarboxylic acid N-Hydroxynaphthalimide triflate 3-Hydroxy-1,8-naphthalic anhydride 8-Methyl-1-naphthalenemethanol
4-Chloro-1,8-naphthalic anhydride 2,3-Naphthalenedicarboxylic acid Transparent Red E2G Fluorescent Yellow Ii (Disperse)

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1,8-Naphthalic anhydride Suppliers

Global Suppliers ( 277)
Supplier Tel Email Country ProdList Advantage
Wuhan xinyangruihe Chemical Technology Co., Ltd. 027-18120580375 18120580375 669797270@qq.com China 5375 58
Jinan Junhe Pharmaceutical Co., Ltd 18653300596 3989432235@qq.com China 298 58
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Beijing dtftchem Technology Co., Ltd. 010-60275820 13031183356 elainezt@sina.com China 1386 62
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Beijing Isomersyn Technology CO;LTD 010-82954736 13391601435 sales@isomersyn.com China 3294 57
Supplier Advantage
Wuhan xinyangruihe Chemical Technology Co., Ltd. 58
Jinan Junhe Pharmaceutical Co., Ltd 58
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Beijing dtftchem Technology Co., Ltd. 62
Energy Chemical 61
Shanghai Hanhong Scientific Co.,Ltd. 64
Chemsky（shanghai）International Co.,Ltd. 50
Beijing Isomersyn Technology CO;LTD 57

View Latest Price from 1,8-Naphthalic anhydride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,8-Naphthalic anhydride pictures 2026-09-17 1,8-Naphthalic anhydride
81-84-5
 $5.00 1kg ≥99% 200mt/year Jinan Finer Chemical Co., Ltd
1,8-Naphthalic anhydride pictures 2026-05-28 1,8-Naphthalic anhydride
81-84-5
 $2.00-5.00 1KG 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
1,8-Naphthalic anhydride pictures 2023-05-04 1,8-Naphthalic anhydride
81-84-5
 $40.00-48.00 1KG 99% 20tons Guangzhou Sunton Biotechnology Co., Ltd.

1,8-Naphthalic anhydride Spectrum

1,8-Naphthalic anhydride(81-84-5)MS1,8-Naphthalic anhydride(81-84-5)1HNMR1,8-Naphthalic anhydride(81-84-5)13CNMR1,8-Naphthalic anhydride(81-84-5)IR11,8-Naphthalic anhydride(81-84-5)IR2

81-84-5 (1,8-Naphthalic anhydride) Related Search:

Dimethylamine Metformin Dimethyl carbonate Erythromycin Estolate Di-tert-butyl dicarbonate
Succinic anhydride Dimethyl fumarate Glutaric anhydride Naphthalene Maleic anhydride
Phthalic anhydride Acetic anhydride 4-Bromo-1,8-naphthalic anhydride 3-Hydroxy-1,8-naphthalic anhydride 4-NITRO-1,8-NAPHTHALIC ANHYDRIDE,4-NITRO-1,8-NAPHTHALIC ANHYDRIDE 95+%
4-Bromo-1,8-naphthalic anhydride 3-Bromo-1,8-naphthalic anhydride 3-Nitro-1,8-naphthalic anhydride Naphthalic Anhydride

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Two1,8-naphthaleneanhydride Naphthalic anh 1,8 Naphthaloic Anhydride ai3-09071 Benzo[de]isochromene-1,3-dione Naphthalenedicarboxylic-1,8-anhydride naphthalenedicarboxylicanhydride naphthalic Naphthalic acid anhydride naphthalicacidanhydride Naphthalicanhydride(form1) pakarli Protect Protect (agrochemical) protect(agrochemical) 1,8-naphthalenediocanhydride 1,8-Naphthoic anhydride 1,8-Napthalic anhydride Naphtho[1,8,8a-c,d]pyran-1,3-dione 1,8-Naphthalenedicarboxylic Anhydride 1H,3H-Naphtho[1,8-cd]pyran-1,3-dione 1,8-Naphthalenedicarboxylic anhydride for synthesis 1,8-NAPHTHALENEDICARBOXYLIC ACID ANHYDRIDE 1,8-NAPHTHALENEDICARBOXYLIC ANHYDRIDE 1,8-NAPHTHALIC ACID ANHYDRIDE 1,8-NAPHTHALIC ANHYDRIDE 1,8-Naphthalic anhydride 98% 1H, 3H-NAPHTHO(1,8-CD)-PYRAN-1,3-DIONE NAPHTHALENE-1,8-DICARBOXYLIC ACID ANHYDRIDE Naphthalene-1,8-dicarboxylic anhydride NAPHTHO[1,8,8A-C,D]PYRAN-1,3-DIONE PROTECT(R) 1,8-naphthallic anhydried benzo[de]isochroman-1,3-dione NaphthalicAnhidride>99% 1,8-Naphthalicanhydride,98% 1,8-Naphthalic 1,8-Dinaphthalene dicarboxylic acid anhydride 1,8-Naphthalic anhydride, Naphtho[1,8,8a-c,d]pyran-1,3-dione Naphthaline-1,8-dicarbonic acid anhydride 1,8-Naphthalic anhydride,97% 1,8-Naphthalic anhyd 1,8-Naphthalic anhydride, 97% 100GR 1,8-Naphthalic anhydride, 97% 500GR Naphthalic anhydrid Naphtho[1,8,8a-c,d]pyran-1,3-dione,1H,3H-Benzo[de]isochromene-1,3-dione 1.8-Anhydride Naphthalene(1.8 Naphthalic Anhydride) 1,8-NaphthaL 1,8-NaphthalicAnhydride> 1,8-Naphthalic Anhydride,99% 1,8-Naphthalic anhydride ISO 9001：2015 REACH 1,8-Naphthalic anhydride 81-84-5 3-oxatricyclo[7.3.1.0,13]trideca-1(13),5,7,9,11-pentaene-2,4-dione 1,8-naphthalene dicarboxylic anhydride (NA) 1,8-Naphthalic Anhydride, ≥ 98.0% 1,8-Naphthalene Anhydride 1H,3H-BENZO[DE]ISOCHROMENE-1,3-DIONE NAPHTHALIC ANHYDRIDE 81-84-5 C12H6O3