3-methyl-2-[4-(4-chlorophenyl)-2-thiazolyl]hydrazone,cyclopentanone,hydrobromide
![3-methyl-2-[4-(4-chlorophenyl)-2-thiazolyl]hydrazone,cyclopentanone,hydrobromide Structure](CAS/20240320/GIF/2321332-57-2.gif)
- CAS No.
- 2321332-57-2
- Chemical Name:
- 3-methyl-2-[4-(4-chlorophenyl)-2-thiazolyl]hydrazone,cyclopentanone,hydrobromide
- Synonyms
- 3-methyl-2-[4-(4-chlorophenyl)-2-thiazolyl]hydrazone,cyclopentanone,hydrobromide;Cyclopentanone, 3-methyl-, 2-[4-(4-chlorophenyl)-2-thiazolyl]hydrazone, hydrobromide (1:1)
- CBNumber:
- CB79043926
- Molecular Formula:
- Molecular Weight:
- 386.74
- MDL Number:
- MOL File:
- 2321332-57-2.mol
- MSDS File:
- SDS
3-methyl-2-[4-(4-chlorophenyl)-2-thiazolyl]hydrazone,cyclopentanone,hydrobromide price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 19828 | CPTH6 (hydrobromide) ≥98% | 2321332-57-2 | 1mg | $41 | 2026-04-30 | Buy |
| Cayman Chemical | 19828 | CPTH6 (hydrobromide) ≥98% | 2321332-57-2 | 5mg | $178 | 2026-04-30 | Buy |
| Cayman Chemical | 19828 | CPTH6 (hydrobromide) ≥98% | 2321332-57-2 | 10mg | $312 | 2026-04-30 | Buy |
| Biosynth | WSD33257 | Cpth6 (hydrobromide) | 2321332-57-2 | 25mg | $1310 | 2026-06-05 | Buy |
| Biosynth | WSD33257 | Cpth6 (hydrobromide) | 2321332-57-2 | 50mg | $1822.5 | 2026-06-05 | Buy |
3-methyl-2-[4-(4-chlorophenyl)-2-thiazolyl]hydrazone,cyclopentanone,hydrobromide Chemical Properties, Uses, Production
Description
CPTH6 is a thiazole derivative that inhibits the lysine acetyltransferase activity of Gcn5 and pCAF but not p300 or CBP.1 It blocks the acetylation of H3/H4 histones and α-tubulin in several leukemia cell lines.1 CPTH6 reduces cell viability, arresting cell cycling in the G0/G1 phase and inducing apoptosis.1 It impairs autophagy in a variety of tumor cell lines, at least in part by altering ATG7-mediated elongation of autophagosomal membranes.2
Uses
CPTH6 hydrobromide is a thiazole derivative which activates apoptotic program and increases autophagic features in human acute myeloid leukemia cell lines. CPTH6 can be used for cancer research[1].
References
1. Trisciuoglio, D., Ragazzoni, Y., Pelosi, A., et al. CPTH6, a thiazole derivative, induces histone hypoacetylation and apoptosis in human leukemia cells Clin. Cancer Res. 18(2),475-486(2012).
2. Ragazzoni, Y., Desideri, M., Gabellini, C., et al. The thiazole derivative CPTH6 impairs autophagy Cell Death Dis. 4(3),e524(2013).
3-methyl-2-[4-(4-chlorophenyl)-2-thiazolyl]hydrazone,cyclopentanone,hydrobromide Preparation Products And Raw materials
Raw materials
Preparation Products
3-methyl-2-[4-(4-chlorophenyl)-2-thiazolyl]hydrazone,cyclopentanone,hydrobromide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai EFE Biological Technology Co., Ltd. | 58 |
| BOC Sciences | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
View Latest Price from 3-methyl-2-[4-(4-chlorophenyl)-2-thiazolyl]hydrazone,cyclopentanone,hydrobromide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-15 | CPTH6 hydrobromide
2321332-57-2
|
$970.00-2500.00 | 10g | TargetMol Chemicals Inc. |
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- CPTH6 hydrobromide
2321332-57-2
- $970.00-2500.00
- TargetMol Chemicals Inc.
