1-butylbiguanide
- CAS No.
- 692-13-7
- Chemical Name:
- 1-butylbiguanide
- Synonyms
- Buformin;DBV;Buformine;W 37;H 224;Glybigid;Butformin;Dibetos B;Butyldiguanide;Butylbiguanide
- CBNumber:
- CB7913312
- Molecular Formula:
- C6H15N5
- Molecular Weight:
- 157.2168
- MDL Number:
- MFCD00242653
- MOL File:
- 692-13-7.mol
- MSDS File:
- SDS
| Melting point | 174-176 °C |
|---|---|
| Boiling point | 271.89°C (rough estimate) |
| Density | 1.0291 (rough estimate) |
| refractive index | 1.8070 (estimate) |
| pka | 12.27±0.10(Predicted) |
| InChI | InChI=1S/C6H15N5/c1-2-3-4-10-6(9)11-5(7)8/h2-4H2,1H3,(H6,7,8,9,10,11) |
| InChIKey | XSEUMFJMFFMCIU-UHFFFAOYSA-N |
| SMILES | C(=N)(NCCCC)NC(=N)N |
| FDA UNII | W2115E9C7B |
| ATC code | A10BA03 |
1-butylbiguanide price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| aablocks | AA006B7X | N-butyl-1-carbamimidamidomethanimidamide ≥98% | 692-13-7 | 100mg | $475 | 2026-05-28 | Buy |
| aablocks | AA006B7X | N-butyl-1-carbamimidamidomethanimidamide ≥98% | 692-13-7 | 250mg | $825 | 2026-05-28 | Buy |
| aablocks | AA006B7X | N-butyl-1-carbamimidamidomethanimidamide ≥98% | 692-13-7 | 500mg | $1338 | 2026-05-28 | Buy |
| aablocks | AA006B7X | N-butyl-1-carbamimidamidomethanimidamide ≥98% | 692-13-7 | 1g | $2200 | 2026-05-28 | Buy |
| American Custom Chemicals Corporation | API0000433 | BUFORMIN 95.00% | 692-13-7 | 0.5G | $675 | 2021-12-16 | Buy |
1-butylbiguanide Chemical Properties,Uses,Production
Uses
Buformin, clinically used for diabetes mellitus, is known to improve resistance to insulin in patients. It suppresses the expression of glyceraldehyde 3-phosphate dehydrogenase
Definition
ChEBI: Buformin is a member of the class of biguanides that is biguanide substituted by a butyl group at position 1. It is an antidiabetic drug with potential antitumor effect. It has a role as a hypoglycemic agent, a geroprotector, a radiosensitizing agent, an antineoplastic agent and an antiviral agent. It is functionally related to a biguanide.
brand name
Adebit;Andebit;Andelit;Andere;Biforon;Bigunal;Biquinal;Bs-5892;Bufonamin;Bulbonin;Diabrin;Dutformin;Gliporal;Insulamin;Krebon;Panformin;Silubin retard;Sindiatil;Tidemol retard;Ziavetine.
World Health Organization (WHO)
Buformin is an analogue of phenformin. See WHO comment for phenformin. (Reference: (WHODI) WHO Drug Information, 2, 4, 1977)
in vivo
Buformin (oral administation; 7.6mmol/kg of chow; 7 days) exhibits significantly reduced tumor volumes and weights, andhinders mammary morphogenesis and proliferation in MMTV-erbB-2 transgenic mice[1]
| Animal Model: | Female MMTV-erbB-2 transgenic mice[1] |
| Dosage: | 7.6mmol/kg |
| Administration: | Oral administation; 7 days |
| Result: | Inhibited mammary syngeneic tumor growth in MMTV-erbB-2 transgenic mice. |
1-butylbiguanide Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Kaitaichuang Pharmaceutical Technology Co., Ltd | 16608035117 | 1350095594@qq.com | China | 39 | 58 |
| LGM Pharma | 1-(800)-881-8210 | inquiries@lgmpharma.com | United States | 2110 | 70 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3493 | 58 |
| Shandong Xiya Chemical Co., Ltd. | 4009903999 13395398332 | sales@xiyashiji.com | China | 20788 | 60 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-17392587031 | 1059@dideu.com | China | 9983 | 58 |
| Hubei Baidu Chemical Co., Ltd | 027-59106051 13627137652 | 1438180055@qq.com | China | 8469 | 58 |
| Hubei Guangao Biotechnology Co., Ltd | 027-02702759223056 18162699093 | 1208480011@qq.com | China | 9508 | 58 |
| TCI (Shanghai) Chemical Trading Co., Ltd. | 021-61109150 | sales@tcisct.com | China | 29717 | 58 |
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