1-(tert-butylamino)-3-(o-cyclopentylphenoxy)propan-2-ol
- CAS No.
- 36507-48-9
- Chemical Name:
- 1-(tert-butylamino)-3-(o-cyclopentylphenoxy)propan-2-ol
- Synonyms
- Penbutolol;(±)-Penbutolol;rac Penbutolol;(+/-)-Penbutolol;rac Penbutolol-d9;Penbutolol Solution, 100ppm;1-(tert-butylamino)-3-(o-cyclopentylphenoxy)propan-2-ol;1-(2-Cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]-2-propanol;2-Propanol, 1-(2-cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]-;2-Propanol, 1-(2-cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]- (9CI)
- CBNumber:
- CB7930751
- Molecular Formula:
- C18H29NO2
- Molecular Weight:
- 291.42836
- MDL Number:
- MFCD00864578
- MOL File:
- 36507-48-9.mol
- MSDS File:
- SDS
| Melting point | 55-75°C |
|---|---|
| Boiling point | 438.2±40.0 °C(Predicted) |
| Density | 1.030±0.06 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | Acetone (Slightly), Chloroform (Slightly), Methanol |
| form | Solid |
| pka | 13.90±0.20(Predicted) |
| color | White to Off-White |
| FDA UNII | 78W62V43DY |
| ATC code | C07AA23 |
1-(tert-butylamino)-3-(o-cyclopentylphenoxy)propan-2-ol price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-P220500-25MG | rac Penbutolol >95%(HPLC) | 36507-48-9 | 25mg | $314 | 2026-06-03 | Buy |
| TRC | TRC-P220500-250MG | rac Penbutolol >95%(HPLC) | 36507-48-9 | 250mg | $2275 | 2026-06-03 | Buy |
| Biosynth | LBA50748 | rac Penbutolol | 36507-48-9 | 100mg | $1128 | 2026-06-04 | Buy |
| ChemScene | CS-0113419 | (±)-Penbutolol | 36507-48-9 | 5mg | $186 | 2026-06-04 | Buy |
| ChemScene | CS-0113419 | (±)-Penbutolol | 36507-48-9 | 10mg | $297 | 2026-06-04 | Buy |
1-(tert-butylamino)-3-(o-cyclopentylphenoxy)propan-2-ol Chemical Properties, Uses, Production
Chemical Properties
White to Off-White Solid
Uses
Labelled Penbutolol (P220500). A β-adrenoceptor antagonist. Antihypertensive.
Enzyme inhibitor
This non-selective antihypertensive b-blocker (FW = 291.43 g/mol; CAS 36507-48-9; IUPAC: (S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)- propan-2-ol), known variously as Levatol, Levatolol, Lobeta, Paginol, Hostabloc, and Betapressin, binds to both b1- and b2-adrenergic receptors, thus exhibiting the sympathomimetic effects of a partial b-adrenergic agonist, while also acting as a serotonin (5-HT1A) receptor antagonist. By blocking b-adrenergic receptors and the sympathetic nervous system, penbutolol decreases heart rate and cardiac output, thereby lowering arterial blood pressure.
IC 50
Beta-1 adrenergic receptor
1-(tert-butylamino)-3-(o-cyclopentylphenoxy)propan-2-ol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Aitixi Biotechnology Co., Ltd | 18721763493 | 2493172863@qq.com | China | 997 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Bsisun HK Imoprt And Export Company Limited | +86-18068513926 | China | 1273 | 55 | |
| Clearsynth Labs Limited | +91-22-26355700 | info@clearsynth.com | India | 9656 | 58 |
| TianJin Alta Scientific Co., Ltd. | 022-65378550-8551 | contact@altascientific.com | China | 2772 | 58 |
| Alta Scientific Co., Ltd. | 022-6537-8550 15522853686 | sales@altasci.com.cn | China | 4508 | 55 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9909 | 65 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
