3-Amino-5-hydroxybenzoic acid hydrochloride
- CAS No.
- 14206-69-0
- Chemical Name:
- 3-Amino-5-hydroxybenzoic acid hydrochloride
- Synonyms
- 3-AMINO-5-HYDROXYBENZOIC ACID HCL;3-Amino-5-hydroxybenzoic acid hydrochloride;3-Amino-5-hydroxybenzoicacidhydrochloride95%;3-Amino-5-hydroxybenzoic acid hydrochloride 95%;Benzoic acid, 3-amino-5-hydroxy-, hydrochloride (1:1);3-Amino-5-hydroxybenzoic acid, Hydrochloric Acid Salt;3-aMino-5-hydroxybenzoic acid hydrochloride hydrate, 95%;3-Carboxy-5-hydroxyanilne hydrochloride, 3-Amino-5-carboxyphenol hydrochloride
- CBNumber:
- CB7957145
- Molecular Formula:
- C7H8ClNO3
- Molecular Weight:
- 189.59632
- MDL Number:
- MFCD00043420
- MOL File:
- 14206-69-0.mol
- MSDS File:
- SDS
| Melting point | 269-272 °C (decomp) |
|---|---|
| storage temp. | Inert atmosphere,Room Temperature |
| Appearance | Light brown to brown Solid |
| InChI | InChI=1S/C7H7NO3.ClH/c8-5-1-4(7(10)11)2-6(9)3-5;/h1-3,9H,8H2,(H,10,11);1H |
| InChIKey | CXESTILCPSBCGQ-UHFFFAOYSA-N |
| SMILES | C1(C(=O)O)=CC(=CC(N)=C1)O.Cl |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22-36/37/38-22 | |||||||||
| Safety Statements | 22-26-36/37/39 | |||||||||
| Hazard Note | Harmful | |||||||||
| HS Code | 2922290090 | |||||||||
| NFPA 704 |
|
3-Amino-5-hydroxybenzoic acid hydrochloride price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | PAA20669 | 3-Amino-5-hydroxybenzoic acid hydrochloride | 14206-69-0 | 5g | $900 | 2026-06-04 | Buy |
| Biosynth | PAA20669 | 3-Amino-5-hydroxybenzoic acid hydrochloride | 14206-69-0 | 10g | $900 | 2026-06-04 | Buy |
| Biosynth | PAA20669 | 3-Amino-5-hydroxybenzoic acid hydrochloride | 14206-69-0 | 2g | $900 | 2026-06-04 | Buy |
| Biosynth | PAA20669 | 3-Amino-5-hydroxybenzoic acid hydrochloride | 14206-69-0 | 25g | $1168.25 | 2026-06-04 | Buy |
| Biosynth | PAA20669 | 3-Amino-5-hydroxybenzoic acid hydrochloride | 14206-69-0 | 50g | $2206.5 | 2026-06-04 | Buy |
3-Amino-5-hydroxybenzoic acid hydrochloride Chemical Properties, Uses, Production
Uses
3-Amino-5-hydroxybenzoic acid, HCl
Synthesis
99-10-5
14206-69-0
Step 1: Synthesis of 3-amino-5-hydroxybenzoic acid hydrochloride A mixture of 3,5-dihydroxybenzoic acid (250.0 g), ammonium chloride (213.0 g) and 28% ammonium hydroxide solution (750.0 mL) was placed in an autoclave and the reaction was stirred at 180 °C for 3 days. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently concentrated under reduced pressure. The concentrated residue was dissolved in 6N hydrochloric acid solution (3.0 L) and the reaction mixture was heated at 100 °C for 24 hours. After that, the reaction mixture was cooled to 70°C~80°C, decolorized by adding activated carbon (30.0 g) and subsequently filtered through a diatomaceous earth pad. The filtrate was concentrated under reduced pressure and the resulting residue was washed twice with 6N hydrochloric acid solution and finally dried under reduced pressure to give 192.0 g of 3-amino-5-hydroxybenzoic acid hydrochloride (yield: 62.4%). 1H-NMR (d6-DMSO) δ 7.81 (s, 1H), 7.69 (s, 1H), 7.56 (s, 1H).
References
[1] Journal of the American Chemical Society, 2010, vol. 132, # 36, p. 12757 - 12765
[2] Patent: US2012/178765, 2012, A1. Location in patent: Page/Page column 11
[3] Synthetic Communications, 1999, vol. 29, # 8, p. 1379 - 1382
[4] Tetrahedron, 1983, vol. 39, # 24, p. 4189 - 4192
[5] Bioorganic and Medicinal Chemistry, 2006, vol. 14, # 7, p. 2242 - 2252
3-Amino-5-hydroxybenzoic acid hydrochloride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 9993 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shanghai civi chemical technology co.,Ltd | 86-21-34053660 | sale@labgogo.com | China | 9853 | 52 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17752 | 75 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 22497 | 55 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd. | +86-28-85122536 85324413 | market@astatech.cn | China | 8016 | 55 |
