Methiothepin mesylate serotinin 5-HT(1) ant
- CAS No.
- 74611-28-2
- Chemical Name:
- Methiothepin mesylate serotinin 5-HT(1) ant
- Synonyms
- methiothepin mesylate salt;Ro 8-6837 mesylate;Metitepine mesylate salt;Methiothepin mesylate, 10 mM in DMSO;Methiothepin mesylate serotinin 5-HT(1) ant;1-[10,11-dihydro-8-(methylthio)dibenzo[b,f]thiepin-10-yl]-4-methylpiperazine mesylate salt;1-Methyl-4-(8-(methylthio)-10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazine methanesulfonate;Methiothepin mesylate 1-Methyl-4-(3-methylsulfanyl-5,6- dihydrobenzo[b][1]benzothiepin-5-yl)piperazine;Metitepine mesylate salt, 1-[10,11-Dihydro-8-(methylthio)dibenzo[b,f]thiepin-10-yl]-4-methylpiperazine mesylate salt;Ro 8-6837,inhibit,Methiothepin mesylate,Serotonin Receptor,Metitepine,Methiothepin,5-HT Receptor,5-hydroxytryptamine Receptor,Inhibitor
- CBNumber:
- CB7972919
- Molecular Formula:
- C20H24N2S2CH3SO3H
- Molecular Weight:
- 0
- MDL Number:
- MFCD00153831
- MOL File:
- 74611-28-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| storage temp. | Store at -20°C |
|---|---|
| solubility | H2O: soluble13mg/mL |
| form | solid |
| color | white |
| Water Solubility | H2O: 13mg/mL |
| InChI | 1S/C20H24N2S2.CH4O3S/c1-21-9-11-22(12-10-21)18-13-15-5-3-4-6-19(15)24-20-8-7-16(23-2)14-17(18)20;1-5(2,3)4/h3-8,14,18H,9-13H2,1-2H3;1H3,(H,2,3,4) |
| InChIKey | CZMDZGZYKOGLJY-UHFFFAOYSA-N |
| SMILES | CS(O)(=O)=O.CSc1ccc2Sc3ccccc3CC(N4CCN(C)CC4)c2c1 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| PPE | Eyeshields, Gloves, type N95 (US) |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
Methiothepin mesylate serotinin 5-HT(1) ant price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M149 | Methiothepin mesylate salt ≥98% (HPLC), solid | 74611-28-2 | 100mg | $146 | 2026-04-30 | Buy |
| Sigma-Aldrich | M149 | Methiothepin mesylate salt ≥98% (HPLC), solid | 74611-28-2 | 250mg | $322 | 2026-04-30 | Buy |
| Usbiological | 454487 | Methiothepin Mesylate Salt | 74611-28-2 | 100mg | $355 | 2026-06-03 | Buy |
| Usbiological | 454487 | Methiothepin Mesylate Salt | 74611-28-2 | 250mg | $531 | 2026-06-03 | Buy |
| ChemScene | CS-0030713 | Methiothepin mesylate 98.80% | 74611-28-2 | 5mg | $40 | 2026-06-04 | Buy |
Methiothepin mesylate serotinin 5-HT(1) ant Chemical Properties, Uses, Production
Uses
Methiothepin mesylate salt has been used to explore the relationship between circulating cells and the niche. It has also been used in serotonin (5-HT) and antagonists in vivo bioassays and in in vivo antagonist and lipopolysaccharide stimulations.
General Description
Methiothepin belongs to a new class of dibenzothiophenes. Methiothepin possesses neuroleptic activity.
Biochem/physiol Actions
Methiothepin mesylate salt is a 5-HT1, 5-HT6, 5-HT7 serotonin receptor antagonist, which blocks serotonin autoreceptors.
IC 50
5-HT1A Receptor: 7.10 (pKd); 5-HT1B Receptor: 7.28 (pKd); 5-HT1C Receptor: 7.56 (pKd); 5-HT1D Receptor: 6.99 (pKd); 5-HT5A Receptor: 7.0 (pKd); 5-HT5B Receptor: 7.8 (pKd); 5-HT6 Receptor: 8.74 (pKd); 5-HT7 Receptor: 8.99 (pKd); 5-HT2A Receptor: 8.50 (pKi); 5-HT2B Receptor: 8.68 (pKi); 5-HT2C Receptor: 8.35 (pKi)
Methiothepin mesylate serotinin 5-HT(1) ant Preparation Products And Raw materials
Raw materials
Preparation Products
Methiothepin mesylate serotinin 5-HT(1) ant Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4859 | 55 | |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Target molecule Corp. | 857-239-0968 | service1@targetmol.com | United States | 2548 | 60 |
| Shanghai Rechem science Co., Ltd. | 021-31433387 15618786686 | sales@rechemscience.com | China | 2969 | 58 |
| Shanghai Chaolan Chemical Technology Center | QQ：65489617 13301690235 | Sales@ATKchemical.com | China | 9729 | 58 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 021-4009004166/18616739031 18616739031 | 3007523370@qq.com | China | 40000 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Changzhou Chenhong Biotechnology Co., Ltd. | +86-0519-85788828 +86-13775037613 | sales@chemrenpharm.com | China | 4083 | 58 |
View Latest Price from Methiothepin mesylate serotinin 5-HT(1) ant manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | Methiothepin mesylate
74611-28-2
|
$31.00-50.00 | 99.48% | 10g | TargetMol Chemicals Inc. |
-
- Methiothepin mesylate
74611-28-2
- $31.00-50.00
- 99.48%
- TargetMol Chemicals Inc.
