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Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate

Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate structure

CAS No.: 175137-27-6

Chemical Name:: Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate

Synonyms: BUTTPARK 46\18-97;Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-;Methyl2-chloro-4-(trifluoromethyl)pyrimidine-5-;2-Chloro-5-(methoxycarbonyl)-4-(trifluoromethyl)pyrimidine;Methyl-2-chloro-4-(trifluoromethyl)pyrimidin-5-carboxylate;METHYL 2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE;Methyl 2-chloro-4-(trifluoromethyl)-5-pyrimidinecarboxylate;Methyl 2-Chloro-4-(trif1uoromethyl) pyridine-5-carboxylate;Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate ,97%;4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]-2-methylbenzoate

CBNumber:: CB8106481

Molecular Formula:: C7H4ClF3N2O2

Molecular Weight:: 240.57

MDL Number:: MFCD00068146

MOL File:: 175137-27-6.mol

Last updated:2026-05-28 02:51:02

Product description	Number	Pack Size	Price
Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate 97%	714372	1g	$50.5
Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate 95%	PC5073	250mg	$21
Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate 95%	PC5073	1g	$28
Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate 95%	PC5073	5g	$96
Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate 95%	PC5073	25g	$340
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Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate Properties

Melting point	253-254 °C
Boiling point	76-78°C 0,5mm
Density	1.491
refractive index	n20/D1.468
Flash point	>110℃
storage temp.	2-8°C
pka	-5.70±0.29(Predicted)
form	liquid
Appearance	Colorless to light yellow Liquid
InChI	1S/C7H4ClF3N2O2/c1-15-5(14)3-2-12-6(8)13-4(3)7(9,10)11/h2H,1H3
InChIKey	VLUBJYUOPNGBOQ-UHFFFAOYSA-N
SMILES	COC(=O)c1cnc(Cl)nc1C(F)(F)F
CAS DataBase Reference	175137-27-6(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H301-H315-H319-H335
Precautionary statements	P301+P310+P330-P302+P352-P305+P351+P338
target organs	Respiratory system
Hazard Codes	Xi,Xn
Risk Statements	36/37/38-20/21/22-22
Safety Statements	26-36/37/39-23-51-24/25-22
RIDADR	UN 2810 6.1 / PGIII
WGK Germany	3
HazardClass	IRRITANT
HS Code	2933599590
Storage Class	6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
Hazard Classifications	Acute Tox. 3 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3

Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate price More Price(57)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	714372	Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate 97%	175137-27-6	1g	$50.5	2026-04-30	Buy
Apolloscientific	PC5073	Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate 95%	175137-27-6	250mg	$21	2026-06-04	Buy
Apolloscientific	PC5073	Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate 95%	175137-27-6	1g	$28	2026-06-04	Buy
Apolloscientific	PC5073	Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate 95%	175137-27-6	5g	$96	2026-06-04	Buy
Apolloscientific	PC5073	Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate 95%	175137-27-6	25g	$340	2026-06-04	Buy

Product number	Packaging	Price	Buy
714372	1g	$50.5	Buy
PC5073	250mg	$21	Buy
PC5073	1g	$28	Buy
PC5073	5g	$96	Buy
PC5073	25g	$340	Buy

Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate Chemical Properties,Uses,Production

Uses

Methyl 2-Chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate is used in the synthetic preparation and discovery of 2-[(2,4-Dichlorophenyl)amino]-N-[(tetrahydro- 2H-pyran-4-yl)methyl]-4-(trifluoromethyl)- 5-pyrimidinecarboxamide (G931520) which is a highly selective CB2 receptor agonist for the treatment of inflammatory and neuropathic pain.

Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate Suppliers

Global( 93)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-81139210 +86-17392587031	1059@dideu.com	China	9996	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52704	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418684 +8618949823763	sales@tnjchem.com	China	25356	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18126	58
GIHI CHEMICALS CO.,LIMITED	+86-571-86217390; +8618058761490	info@gihichemicals.com	China	49897	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Shaanxi Dideu Medichem Co. Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Hebei Chuanghai Biotechnology Co., Ltd	58
GIHI CHEMICALS CO.,LIMITED	58

View Lastest Price from Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-06-25	Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate 175137-27-6	$1.10	1g	99.0% min	100 tons min	Shaanxi Dideu Medichem Co. Ltd
	2020-01-13	Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate 175137-27-6	$1.00	1KG	98%-99.9%	200kg	Career Henan Chemical Co

Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate
175137-27-6
$1.10
99.0% min
Shaanxi Dideu Medichem Co. Ltd

Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate
175137-27-6
$1.00
98%-99.9%
Career Henan Chemical Co

Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate Spectrum

Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate(175137-27-6)¹HNMR

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METHYL PYRIMIDINE-5-CARBOXYLATE 2-Chloro-4-(trifluoromethyl)pyrimidine BENZYL 2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE

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BUTTPARK 46\18-97 METHYL 2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE Methyl2-chloro-4-(trifluoromethyl)pyrimidine-5- 4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]-2-methylbenzoate Methyl 2-chloro-4-(trifluoromethyl)pyrimidine- Methyl 2-Chloro-4-(trif1uoromethyl) pyridine-5-carboxylate Methyl 2-chloro-4-(trifluoromethyl)-5-pyrimidinecarboxylate 2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic acid methyl ester Methyl-2-chloro-4-(trifluoromethyl)pyrimidin-5-carboxylate Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate ,97% 2-Chloro-5-(methoxycarbonyl)-4-(trifluoromethyl)pyrimidine Methyl 2-chloro-4-(trifluoroMethyl)pyriMidine-5-carboxylate 5-Pyrimidinecarboxylic acid, 2-chloro-4-(trifluoromethyl)-, methyl ester Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate ISO 9001：2015 REACH 5-Pyrimidinecarboxylic acid, 2-chloro-4-(trifluoromethyl)-, methyl ester (9CI, ACI) 2-chloro-4-(trifluoromethyl)-5-Pyrimidinecarboxylic acid methyl ester (9CI ACI) 175137-27-6 Esters Pyrazines, Pyrimidines & Pyridazines Heterocycle