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ChemicalBook >> CAS DataBase List >>1,3,4-Oxadiazole, 2-(1,3-benzodioxol-5-yl)-5-[[[4,5-dihydro-2-(4-methoxyphenyl)-5-thiazolyl]methyl]thio]-

1,3,4-Oxadiazole, 2-(1,3-benzodioxol-5-yl)-5-[[[4,5-dihydro-2-(4-methoxyphenyl)-5-thiazolyl]methyl]thio]-

1,3,4-Oxadiazole, 2-(1,3-benzodioxol-5-yl)-5-[[[4,5-dihydro-2-(4-methoxyphenyl)-5-thiazolyl]methyl]thio]- Structure
1,3,4-Oxadiazole, 2-(1,3-benzodioxol-5-yl)-5-[[[4,5-dihydro-2-(4-methoxyphenyl)-5-thiazolyl]methyl]thio]- structure
CAS No.
745033-86-7
Chemical Name:
1,3,4-Oxadiazole, 2-(1,3-benzodioxol-5-yl)-5-[[[4,5-dihydro-2-(4-methoxyphenyl)-5-thiazolyl]methyl]thio]-
Synonyms
WAY-624876;Antileishmanial agent-23;1,3,4-Oxadiazole, 2-(1,3-benzodioxol-5-yl)-5-[[[4,5-dihydro-2-(4-methoxyphenyl)-5-thiazolyl]methyl]thio]-
CBNumber:
CB811648024
Molecular Formula:
C20H17N3O4S2
Molecular Weight:
427.5
MDL Number:
MOL File:
745033-86-7.mol
Last updated:2026-05-11 15:21:01
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1,3,4-Oxadiazole, 2-(1,3-benzodioxol-5-yl)-5-[[[4,5-dihydro-2-(4-methoxyphenyl)-5-thiazolyl]methyl]thio]- Properties

Boiling point 623.9±65.0 °C(Predicted)
Density 1.52±0.1 g/cm3(Predicted)
pka 3.94±0.40(Predicted)

1,3,4-Oxadiazole, 2-(1,3-benzodioxol-5-yl)-5-[[[4,5-dihydro-2-(4-methoxyphenyl)-5-thiazolyl]methyl]thio]- Chemical Properties, Uses, Production

Uses

Antileishmanial agent-23 (compound G1/9) is a potent and selective trypanothione reductase (TR) inhibitor, with an IC50 of 2.24 ± 0.52 μM. Antileishmanial agent-23 inhibits the growth of Leishmania, Trypanosoma cruzi, and Trypanosoma brucei[1].

Definition

ChEBI: 2-(1,3-benzodioxol-5-yl)-5-[[2-(4-methoxyphenyl)-4,5-dihydrothiazol-5-yl]methylthio]-1,3,4-oxadiazole is a member of benzodioxoles.

References

[1] Ilari A, et al. Toward a Drug Against All Kinetoplastids: From LeishBox to Specific and Potent Trypanothione Reductase Inhibitors. Mol Pharm. 2018 Aug 6;15(8):3069-3078. DOI:10.1021/acs.molpharmaceut.8b00185

1,3,4-Oxadiazole, 2-(1,3-benzodioxol-5-yl)-5-[[[4,5-dihydro-2-(4-methoxyphenyl)-5-thiazolyl]methyl]thio]- Preparation Products And Raw materials

Raw materials

Preparation Products

1,3,4-Oxadiazole, 2-(1,3-benzodioxol-5-yl)-5-[[[4,5-dihydro-2-(4-methoxyphenyl)-5-thiazolyl]methyl]thio]- Suppliers

Global Suppliers ( 7)
Supplier Tel Email Country ProdList Advantage
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
ShangHai ChuanQian Chemcial Technique Centre 15869524721 3525679403@qq.com China 4565 58
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 4999 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Zhejiang Huida Biotech Co., Ltd. 0571-89903022 18679456698 zilong@hizyme.com China 7853 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Aladdin Scientific tp@aladdinsci.com United States 50089 58
Supplier Advantage
Shanghai YuanYe Biotechnology Co., Ltd. 60
ShangHai ChuanQian Chemcial Technique Centre 58
Jinan Jiuli Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
Zhejiang Huida Biotech Co., Ltd. 58
TargetMol Chemicals Inc. 58
Aladdin Scientific 58

View Latest Price from 1,3,4-Oxadiazole, 2-(1,3-benzodioxol-5-yl)-5-[[[4,5-dihydro-2-(4-methoxyphenyl)-5-thiazolyl]methyl]thio]- manufacturers

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Antileishmanial agent-23 pictures 2026-05-11 Antileishmanial agent-23
745033-86-7
 10g TargetMol Chemicals Inc.

745033-86-7 (1,3,4-Oxadiazole, 2-(1,3-benzodioxol-5-yl)-5-[[[4,5-dihydro-2-(4-methoxyphenyl)-5-thiazolyl]methyl]thio]-) Related Search:

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1,3,4-Oxadiazole, 2-(1,3-benzodioxol-5-yl)-5-[[[4,5-dihydro-2-(4-methoxyphenyl)-5-thiazolyl]methyl]thio]- WAY-624876 Antileishmanial agent-23 745033-86-7