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7-Chloro-1H-pyrrolo[3,2-b]pyridine

7-Chloro-1H-pyrrolo[3,2-b]pyridine structure

CAS No.: 357263-48-0

Chemical Name:: 7-Chloro-1H-pyrrolo[3,2-b]pyridine

Synonyms: 7-Chloro-4-azaindole;7-chloro-1H-pyrrolo[3;7-Chloro-4-azaindole 7-;7-Chloro-1H-pyrrolo[3,2-b...;7-CHLORO-1H-PYRROLO[3,2-B]PYRIDINE;1H-Pyrrolo[3,2-b]pyridine, 7-chloro-;7-CHLORO-1H-PYRROLO[3,2-B]PYRIDINE ISO 9001：2015 REACH

CBNumber:: CB8119218

Molecular Formula:: C7H5ClN2

Molecular Weight:: 152.58

MDL Number:: MFCD08234945

MOL File:: 357263-48-0.mol

MSDS File:: SDS

Last updated:2026-05-28 03:10:04

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7-Chloro-1H-pyrrolo[3,2-b]pyridine Properties

Boiling point	290.6±20.0 °C(Predicted)
Density	1.425
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
pka	13.08±0.40(Predicted)
Appearance	Off-white to yellow Solid
InChI	InChI=1S/C7H5ClN2/c8-5-1-3-9-6-2-4-10-7(5)6/h1-4,10H
InChIKey	ZBEYLQBHTDNDDR-UHFFFAOYSA-N
SMILES	C12C=CNC1=C(Cl)C=CN=2

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
HS Code	2933998090

7-Chloro-1H-pyrrolo[3,2-b]pyridine price More Price(57)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Apolloscientific	OR321484	7-Chloro-1H-pyrrolo[3,2-b]pyridine 97%	357263-48-0	250mg	$21	2026-06-04	Buy
Apolloscientific	OR321484	7-Chloro-1H-pyrrolo[3,2-b]pyridine 97%	357263-48-0	1g	$35	2026-06-04	Buy
Apolloscientific	OR321484	7-Chloro-1H-pyrrolo[3,2-b]pyridine 97%	357263-48-0	5g	$127	2026-06-04	Buy
Apolloscientific	OR321484	7-Chloro-1H-pyrrolo[3,2-b]pyridine 97%	357263-48-0	25g	$505	2026-06-04	Buy
Activate Scientific	AS31971	7-Chloro-4-azaindole 97%	357263-48-0	1g	$63	2026-06-04	Buy

Product number	Packaging	Price	Buy
OR321484	250mg	$21	Buy
OR321484	1g	$35	Buy
OR321484	5g	$127	Buy
OR321484	25g	$505	Buy
AS31971	1g	$63	Buy

7-Chloro-1H-pyrrolo[3,2-b]pyridine Chemical Properties, Uses, Production

Synthesis

1116136-36-7

357263-48-0

General procedure for the synthesis of 7-chloro-1H-pyrrolo[3,2-b]pyridine from 4-azaindole-4-oxide: 1H-pyrrolo[3,2-b]pyridine-4-oxide (33 g, 246.27 mmol, 1.00 equiv.) was added to a 1000 mL round bottom flask. To the mixture was added phosphorus trichloride (POCl3, 165.3 g). The resulting solution was stirred in an oil bath at 80 °C for overnight reaction. Upon completion of the reaction, the reaction mixture was quenched by slowly adding 400 mL of water. The pH of the reaction mixture was adjusted to 7-8 with sodium hydroxide (NaOH) solution. the aqueous phase was extracted three times with ethyl acetate (EtOAc, 400 mL), the organic layers were combined and dried over anhydrous sodium sulfate (Na2SO4). After filtration, the organic phase was concentrated under reduced pressure using a rotary evaporator to give 33 g (88% yield) of 7-chloro-1H-pyrrolo[3,2-b]pyridine as a yellow solid.

References

[1] Patent: WO2009/23844, 2009, A2. Location in patent: Page/Page column 140-141
[2] Patent: WO2017/59080, 2017, A1. Location in patent: Page/Page column 195
[3] Journal of Medicinal Chemistry, 2014, vol. 57, # 13, p. 5728 - 5737
[4] Patent: US2015/94328, 2015, A1. Location in patent: Paragraph 0363; 0364; 0365
[5] Patent: WO2015/49574, 2015, A1. Location in patent: Page/Page column 40

7-Chloro-1H-pyrrolo[3,2-b]pyridine Preparation Products And Raw materials

Raw materials

Vinylmagnesium bromide 1H-Pyrrolo[3,2-b]pyridine, 4-oxide 4-Chloro-3-nitropyridine Sodium hydroxide

Preparation Products

7-Chloro-1H-pyrrolo[3,2-b]pyridine Suppliers

Global Suppliers ( 136)

Supplier	Tel	Email	Country	ProdList	Advantage
Shijiazhuang suchen Chemical Technology Co. LTD	186-33933494 18032288352	1130239@qq.com	China	192	60
JinYan Chemicals(ShangHai) Co.,Ltd.	13817811078	sales@jingyan-chemical.com	China	9963	60
Pure Chemistry Scientific Inc.	001-857-928-2050 or 1-888-588-9418	sales@chemreagents.com	United States	10174	62
Tongchuang Pharma(Suzhou). Co., Ltd.	0512-63263366 18912765016	tongtf110@sina.com	China	984	62
Wuhan ariel chemical Co., LTD.	18986259541 18986259541	sales@3stc.com	China	3828	58
Hangzhou Sage Chemical Co., Ltd.	+86057186818502 13588463833	info@sagechem.com	China	10265	58
Wuhan TCASChem Technology Co., Ltd.	027-86697669 13986148687	sales@tcaschem.com	China	4000	55
Shanghai Topbiochem Technology Co., Ltd	+86-21-60341587	sales@topbiochem.com	China	6166	58
Nanjing Norris-Pharm Technology Co., Ltd	13901585132	sales@norris-pharm.com	China	8869	55
Runpharm Technology Limited	18171398856 2968382473	service@runpharm.com	China	716	55

Supplier	Advantage
Shijiazhuang suchen Chemical Technology Co. LTD	60
JinYan Chemicals(ShangHai) Co.,Ltd.	60
Pure Chemistry Scientific Inc.	62
Tongchuang Pharma(Suzhou). Co., Ltd.	62
Wuhan ariel chemical Co., LTD.	58
Hangzhou Sage Chemical Co., Ltd.	58
Wuhan TCASChem Technology Co., Ltd.	55
Shanghai Topbiochem Technology Co., Ltd	58
Nanjing Norris-Pharm Technology Co., Ltd	55
Runpharm Technology Limited	55

View Latest Price from 7-Chloro-1H-pyrrolo[3,2-b]pyridine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-09-02	7-CHLORO-1H-PYRROLO[3,2-B]PYRIDINE 357263-48-0		1KG	98$	200kg	Career Henan Chemical Co

7-CHLORO-1H-PYRROLO[3,2-B]PYRIDINE
357263-48-0
$0.00
98$
Career Henan Chemical Co

7-Chloro-1H-pyrrolo[3,2-b]pyridine Spectrum

7-CHLORO-1H-PYRROLO[3,2-B]PYRIDINE(357263-48-0)¹HNMR

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7-CHLORO-1H-PYRROLO[3,2-B]PYRIDINE 7-Chloro-4-azaindole 7-Chloro-4-azaindole 7- 7-Chloro-1H-pyrrolo[3,2-b... 7-chloro-1H-pyrrolo[3 1H-Pyrrolo[3,2-b]pyridine, 7-chloro- 7-CHLORO-1H-PYRROLO[3,2-B]PYRIDINE ISO 9001：2015 REACH 357263-48-0 257263-48-0 Azaindoles